CN108915971B - Mobile phase ratio control method and device, high pressure constant flow pump and storage medium - Google Patents
Mobile phase ratio control method and device, high pressure constant flow pump and storage medium Download PDFInfo
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- CN108915971B CN108915971B CN201810538291.8A CN201810538291A CN108915971B CN 108915971 B CN108915971 B CN 108915971B CN 201810538291 A CN201810538291 A CN 201810538291A CN 108915971 B CN108915971 B CN 108915971B
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- 238000000034 method Methods 0.000 title claims abstract description 40
- 239000007788 liquid Substances 0.000 claims abstract description 78
- 238000010521 absorption reaction Methods 0.000 claims abstract description 10
- 238000004364 calculation method Methods 0.000 claims description 8
- 238000005259 measurement Methods 0.000 claims description 4
- 238000010586 diagram Methods 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 4
- 238000007792 addition Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003480 eluent Substances 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 102000017011 Glycated Hemoglobin A Human genes 0.000 description 1
- 108010014663 Glycated Hemoglobin A Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
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- 238000009530 blood pressure measurement Methods 0.000 description 1
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- 230000010349 pulsation Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/10—Valves; Arrangement of valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
- F04B17/03—Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/06—Control using electricity
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B51/00—Testing machines, pumps, or pumping installations
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
- F04B9/02—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical
- F04B9/04—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical the means being cams, eccentrics or pin-and-slot mechanisms
- F04B9/042—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical the means being cams, eccentrics or pin-and-slot mechanisms the means being cams
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- Control Of Positive-Displacement Pumps (AREA)
Abstract
The present invention discloses a kind of mobile phase ratio control method and device, high pressure constant flow pump and storage medium.The mobile phase ratio control method includes: to obtain the number and mixed proportion of mobile phase to be mixed；Corresponding relationship between the camshaft angle and liquid absorption amount of the high pressure constant flow pump demarcated according to mixed proportion and in advance, obtains one or more handoff angle, and handoff angle is camshaft angle when two mobile phases are executed with handover operation；Current camshaft angle is matched with one or more handoff angle；According to matching result, the absorption object of high pressure constant flow pump is mutually switched into next mobile phase corresponding with the handoff angle of successful match from now thereof.Using the technical solution in the embodiment of the present invention, the liquid mixed-precision of high pressure constant flow pump can be improved.
Description
Technical Field
The invention relates to the field of liquid analysis, in particular to a flow phase ratio control method and device, a high-pressure constant flow pump and a storage medium.
Background
In some liquid analyzers, two or more liquids need to be mixed to perform elution processing on a sample, thereby achieving the purpose of separating the sample. Taking a blood analyzer as an example, hemoglobin in a blood sample can be separated by an elution process.
In order to mix the two or more than two liquids according to a predetermined ratio, in the prior art, a proportional valve of a high-pressure constant flow pump needs to be controlled according to a predetermined time ratio to perform switching operation on the two or more than two liquids, so as to obtain an eluent meeting the mixing requirement.
However, the inventor of the present application finds that the high-pressure constant-flow pump includes a suction stroke and an idle stroke in one stroke cycle, and the high-pressure constant-flow pump performs a liquid suction operation only in the suction stroke, whereas the method of the prior art for determining the time ratio of the predetermined time needs to incorporate the calculation of the suction stroke time and the idle stroke time at the same time, and adds redundant time to the control operation of the proportional valve, resulting in low liquid mixing precision of the high-pressure constant-flow pump.
Disclosure of Invention
The embodiment of the invention provides a mobile phase proportion control method and device, a high-pressure constant flow pump and a storage medium, which can improve the liquid mixing precision of the high-pressure constant flow pump.
In a first aspect, an embodiment of the present invention provides a mobile phase ratio control method, where the mobile phase ratio control method includes:
obtaining the number and the mixing proportion of the mobile phases to be mixed;
obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the high-pressure constant flow pump and the liquid suction amount, wherein the switching angles are camshaft angles when switching operation is performed on the two mobile phases;
matching the current camshaft angle with one or more switching angles;
and switching the suction object of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle of successful matching according to the matching result.
In one possible embodiment of the first aspect, the plunger rod of the high-pressure constant-flow pump is driven by the cam shaft to reciprocate linearly; before obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the high-pressure constant flow pump and the liquid suction amount, the method further comprises the following steps: and when the plunger rod is in the descending lift range, taking the product of the descending amount of the position of the plunger rod corresponding to the angle of the camshaft and the sectional area of the plunger rod as the liquid suction amount corresponding to the angle of the camshaft to obtain the corresponding relation between the angle of the camshaft of the pre-calibrated high-pressure constant flow pump and the liquid suction amount.
In a possible embodiment of the first aspect, obtaining one or more switching angles according to the mixing ratio and the correspondence between the camshaft angle of the pre-calibrated high-pressure constant flow pump and the liquid suction amount includes: taking the angle interval of the camshaft when the liquid absorption amount in the stroke cycle is not 0 as an absorption interval; dividing the suction interval by using the mixing proportion to obtain suction subintervals corresponding to the flows; and taking the camshaft angle corresponding to the node between the adjacent sucking subintervals as the switching angle of the two mobile phases corresponding to the adjacent sucking subintervals.
In a possible implementation manner of the first aspect, after switching the suction target of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle at which the matching is successful according to the matching result, the method further includes: measuring the liquid pressure in a suction pipeline of the high-pressure constant flow pump; and if the liquid pressure is not within the preset pressure range, compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value.
In a second aspect, an embodiment of the present invention provides a flow phase ratio control apparatus, including:
the acquisition module is used for acquiring the number and the mixing proportion of the mobile phases to be mixed;
the first calculation module is used for obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the high-pressure constant flow pump and the liquid absorption amount, wherein the switching angles are camshaft angles when switching operation is performed on two mobile phases;
the matching module is used for matching the current camshaft angle with one or more switching angles;
and the proportional valve is used for switching the suction object of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle of successful matching according to the matching result.
In a possible embodiment of the second aspect, the plunger rod of the high-pressure constant-flow pump is driven by the cam shaft to reciprocate linearly; the device also comprises a second calculation module, wherein the second calculation module is used for taking the product of the descending amount of the position of the plunger rod corresponding to the angle of the camshaft and the sectional area of the plunger rod when the plunger rod is in the descending lift as the liquid suction amount corresponding to the angle of the camshaft to obtain the corresponding relation between the angle of the camshaft of the pre-calibrated high-pressure constant flow pump and the liquid suction amount.
In one possible embodiment of the second aspect, the apparatus further comprises: the pressure measuring module is used for measuring the liquid pressure in the suction pipeline of the high-pressure constant flow pump; and the compensation module is used for compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value if the liquid pressure is not within the preset pressure range.
In one possible embodiment of the second aspect, the apparatus further comprises: and the angle measuring module is used for measuring the angle of the camshaft.
In one possible embodiment of the second aspect, a notch is provided at a lowest point position of a lift curve of the camshaft, and the angle measurement module comprises a photoelectric sensor and a processor; the photoelectric sensor comprises a transmitter and a receiver which are fixedly arranged relative to two sides of the camshaft, wherein the transmitter is used for transmitting an optical-electrical signal, and the receiver is used for acquiring the photoelectric signal and transmitting the acquired photoelectric signal to the processor; the processor obtains the camshaft angle according to the collected photoelectric signal.
In a third aspect, embodiments of the present invention provide a high-pressure constant flow pump, which includes the flow ratio control device as described above.
A fourth aspect. An embodiment of the present invention provides a computer-readable storage medium on which a program is stored, the program implementing the flow phase ratio control method as described above when executed by a processor.
As described above, when there is a mobile phase mixing requirement, the number and mixing ratio of the mobile phases to be mixed can be obtained, and then one or more switching angles can be obtained according to the mixing ratio and the corresponding relationship between the camshaft angle of the high-pressure constant flow pump and the liquid suction amount that is calibrated in advance. And then, only the detected current camshaft angle and the detected switching angle are matched, and then the suction object of the high-pressure constant flow pump is switched from the current mobile phase to the next mobile phase corresponding to the successfully matched switching angle according to the matching result, so that the mixed liquid with the required mixing proportion height can be obtained.
Compared with the prior art that the proportional valve of the high-pressure constant flow pump needs to be controlled according to the preset time proportion to perform switching operation on two or more elements of liquid, the switching operation of the high-pressure constant flow pump is performed based on the angle of the camshaft, the switching operation of the high-pressure constant flow pump can be performed based on the relation between the time and the proportional valve, and therefore liquid mixing accuracy of the high-pressure constant flow pump is improved.
Drawings
The present invention will be better understood from the following description of specific embodiments thereof taken in conjunction with the accompanying drawings, in which like or similar reference characters designate like or similar features.
FIG. 1 is a schematic diagram illustrating the correspondence between plunger rod position and camshaft angle provided by a first embodiment of the present invention;
FIG. 2 is a schematic structural view of a camshaft corresponding to FIG. 1;
FIG. 3 is a flow chart of a mobile phase ratio control method according to a third embodiment of the present invention;
FIG. 4 is one of schematic views corresponding to FIG. 1 showing a correspondence between a camshaft angle and a liquid suction amount;
fig. 5 is a schematic flow chart of a mobile phase ratio control method according to a fifth embodiment of the present invention;
FIG. 6 is a second schematic view corresponding to FIG. 1 showing the correspondence between the angle of the cam shaft and the amount of liquid sucked;
FIG. 7 is a third schematic view showing the correspondence between the angle of the cam shaft and the amount of liquid sucked in, corresponding to FIG. 1;
fig. 8 is a schematic structural view of a camshaft angle measuring device according to an eighth embodiment of the present invention;
fig. 9 is a schematic structural diagram of a flow phase ratio control device according to a ninth embodiment of the present invention.
Detailed Description
Features and exemplary embodiments of various aspects of the present invention will be described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of the present invention.
The embodiment of the invention provides a mobile phase proportion control method and device, a high-pressure constant flow pump and a storage medium, which are used in a high-pressure constant flow pump of a liquid chromatograph or a glycosylated hemoglobin analyzer. By adopting the technical scheme in the embodiment of the invention, the liquid mixing precision of the high-pressure constant-flow pump can be improved, and the eluent meeting the mixing requirement can be obtained.
The high-pressure constant flow pump is a reciprocating double-cam plunger pump controlled by a microcomputer, and has the characteristics of convenient operation, stable flow rate, small pressure pulsation and low failure rate. The plunger rod of the high-pressure constant-flow pump is driven by the camshaft to do linear reciprocating motion.
Fig. 1 is a schematic diagram showing the correspondence between the position of the plunger rod and the angle of the cam shaft according to the first embodiment of the present invention, and shows the correspondence between the angle of the cam shaft and the position of the plunger rod during one rotation period of the cam shaft.
The abscissa shown in fig. 1 is the camshaft angle and the ordinate is the plunger rod position.
As can be seen from fig. 1, during one rotation cycle of the camshaft, the plunger rod first rises and then falls. In the rising process of the plunger rod, the high-pressure constant flow pump executes liquid pushing operation; during the descending process of the plunger rod, the high-pressure constant flow pump performs liquid suction operation.
In fig. 1, 0 ° represents the lowest point of lift of the plunger rod, and P1 represents the highest point of lift of the plunger rod, and in one example, P1 may be 96 °.
Fig. 2 is a schematic structural view of a camshaft corresponding to fig. 1. As shown in fig. 2, the camshaft rotates clockwise, the plunger rod is just at the lowest lift point when the camshaft rotates to 0 °, and the plunger rod is just at the highest lift point when the camshaft rotates to the P1 position.
In one example, the thickness of the crankshaft shaft at a camshaft angle of 0 ° is 10mm, and the thickness of the shaft at a camshaft angle of P1 may be 12 mm.
Fig. 3 is a schematic flow chart of a mobile phase ratio control method according to a third embodiment of the present invention. As shown in fig. 3, the mobile phase ratio control method includes steps 301 to 304.
In step 301, the number of mobile phases to be mixed and the mixing ratio are acquired.
In step 302, one or more switching angles are obtained according to the mixing ratio and the corresponding relationship between the camshaft angle of the pre-calibrated high-pressure constant flow pump and the liquid suction amount, and the switching angles are the camshaft angles when the switching operation is performed on the two mobile phases.
For example, if the number of mobile phases to be mixed is 2, a switching angle can be obtained. If the number of mobile phases to be mixed is 4, three switching angles can be obtained.
In step 303, the current camshaft angle is matched to one or more switching angles.
In step 304, according to the matching result, the suction object of the high-pressure constant flow pump is switched from the current mobile phase to the next mobile phase corresponding to the switching angle at which the matching is successful.
As described above, when there is a mobile phase mixing requirement, the number and mixing ratio of the mobile phases to be mixed can be obtained, and then one or more switching angles can be obtained according to the mixing ratio and the corresponding relationship between the camshaft angle of the high-pressure constant flow pump and the liquid suction amount that is calibrated in advance. And then, only the detected current camshaft angle and the detected switching angle are matched, and then the suction object of the high-pressure constant flow pump is switched from the current mobile phase to the next mobile phase corresponding to the successfully matched switching angle according to the matching result, so that the mixed liquid with the required mixing proportion height can be obtained.
Compared with the prior art that the proportional valve of the high-pressure constant flow pump needs to be controlled according to the preset time proportion to perform switching operation on two or more elements of liquid, the switching operation of the high-pressure constant flow pump is performed based on the angle of the camshaft, the switching operation of the high-pressure constant flow pump can be performed based on the relation between the time and the proportional valve, and therefore liquid mixing accuracy of the high-pressure constant flow pump is improved.
In an optional embodiment, when the plunger rod is in the descending lift range, the product of the descending amount of the position of the plunger rod corresponding to the angle of the camshaft and the sectional area of the plunger rod can be used as the liquid suction amount corresponding to the angle of the camshaft, so that the corresponding relation between the angle of the camshaft of the pre-calibrated high-pressure constant flow pump and the liquid suction amount can be obtained.
With reference to fig. 1, when the plunger rod is in down-lift, the corresponding camshaft angle is in the range P1, 360 °. Specifically, the product of the plunger rod descending amount and the plunger rod cross-sectional area corresponding to each camshaft angle in the interval of [ P1, 360 ° ] can be used as the liquid suction amount corresponding to the plunger rod position, so as to obtain the corresponding relationship between the camshaft angle and the liquid suction amount of the pre-calibrated high-pressure constant flow pump.
Fig. 4 is a schematic view showing a correspondence relationship between the cam shaft angle and the liquid suction amount corresponding to fig. 1. The abscissa shown in fig. 4 is the camshaft angle and the ordinate is the liquid suction amount.
As shown in fig. 4, when the camshaft angle is P1, the high-pressure constant flow pump starts the suction operation, and the liquid suction amount is 0, and when the camshaft angle is 360, the high-pressure constant flow pump ends the suction operation, and the liquid suction amount is 100%.
Fig. 5 is a schematic flow chart of a mobile phase ratio control method according to a fifth embodiment of the present invention. Fig. 5 differs from fig. 3 in that the steps in fig. 3 can be subdivided into steps 3021 to 3023 in fig. 5.
In step 3021, the suction interval is set to be a camshaft angle interval when the amount of suction in the stroke cycle is not 0.
With reference to fig. 1 and 4, an angular interval of the camshaft angle [ P1, 360 ° ] when the plunger rod is in the lowering lift may be used as the suction interval.
In step 3022, the aspiration segment is divided by the mixing ratio to obtain aspiration sub-segments corresponding to each flow.
In step 3023, the camshaft angle corresponding to the node between the adjacent suction subintervals is used as the switching angle of the two mobile phases corresponding to the adjacent suction subintervals.
In one example, as shown in FIG. 6, if the mobile phases to be mixed include A-phase and B-phase, where A-phase is 60% and B-phase is 40%, two extraction subintervals [ P1, P2] and (P2, 360 ° ] can be obtained for extracting A-phase and B-phase, respectively, the width ratio of these two subintervals is 3/2 and P2 is the switching angle corresponding to A-phase and B-phase.
The mobile phase proportion control method based on fig. 6 can be described as:
and starting the high-pressure constant flow pump motor, acquiring the angle Pt of the cam shaft in real time in each stroke cycle of the high-pressure constant flow pump, performing suction operation on the phase A by the high-pressure constant flow pump when the Pt is equal to P1, and switching a suction object from the phase A to the phase B by the high-pressure constant flow pump when the Pt is equal to P2. When Pt equals P1, the next proportional control cycle is entered.
In another example, as shown in fig. 7, if the mobile phases to be mixed include an a phase, a B phase, a C phase, and a D phase, the a phase accounting for 50%, the B phase accounting for 30%, the C phase accounting for 15%, and the D phase accounting for 5%, four sucking subintervals [ P1, P3], (P3, P4], (P4, P5], and (P5, 360 ° ]) for sucking the a phase, the B phase, the C phase, and the D phase, respectively, may be obtained, the width ratios of the four subintervals being 10/6/3/1, P3 being a switching angle corresponding to the a phase and the B phase, P4 being a switching angle corresponding to the B phase and the C phase, and P5 being a switching angle corresponding to the C phase and the D phase.
The mobile phase proportion control method based on fig. 7 can be described as: starting a high-pressure constant flow pump motor, acquiring a camshaft angle Pt in real time in each stroke cycle of the high-pressure constant flow pump, performing suction operation on the phase A by the high-pressure constant flow pump when the Pt is equal to P1, switching a suction object from the phase A to the phase B by the high-pressure constant flow pump when the Pt is equal to P3, switching the suction object from the phase B to the phase C by the high-pressure constant flow pump when the Pt is equal to P4, and switching the suction object from the phase C to the phase D by the high-pressure constant flow pump when the Pt is equal to P5. When Pt equals P1, the next proportional control cycle is entered.
In the embodiment of the present invention, the angle measuring device for measuring the angle of the camshaft includes an encoder, a photoelectric sensor, a position sensor, and the like.
Fig. 8 is a schematic structural diagram of a camshaft angle measuring device according to an eighth embodiment of the present invention, which is used to specifically show the arrangement of an angle measuring device based on a photoelectric sensor.
As shown in fig. 8, a notch 801 may be provided on the camshaft, and the photoelectric sensor 802 includes a transmitter and a receiver fixedly provided on both sides of the camshaft, the transmitter is used for transmitting an optical electrical signal, and the receiver is used for collecting the optical electrical signal. After a motor of the high-voltage constant-current pump is started, the angle of the camshaft can be obtained through an optical signal collected by the receiver.
In an alternative embodiment, the notch 801 may be located at a position corresponding to the lowest point of the lift curve of the camshaft (such as the position P1 in fig. 2).
In an optional embodiment, after switching the suction target of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle at which the matching is successful, the method for controlling the flow phase ratio may further include: and measuring the liquid pressure in the suction pipeline of the high-pressure constant flow pump, and if the liquid pressure is not within the preset pressure range, compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value so as to compensate the flow of the high-pressure constant flow pump and further improve the liquid mixing precision of the high-pressure constant flow pump.
As described above, since the control signal is obtained according to the curve of the angle of the camshaft of the high-pressure pump and the position of the plunger rod and converted into the curve of the relationship between the percentage of the liquid absorption amount and the position without dimension, the accurate liquid ratio can be obtained only by finding the angle of the camshaft for switching the proportional valve at the corresponding ratio and then switching the proportional valve at the corresponding angle. That is, in the embodiment of the present invention, the current motor rotation angle (camshaft angle) is used as a condition for switching the electromagnetic valve, so that the relationship with time can be removed, and the influence of the non-uniform operation of the motor on the non-linear change of the suction volume can be avoided. Therefore, the embodiment of the invention can control the liquid ratio of each mobile phase with high precision and is suitable for different motion curves of the high-pressure pump.
In addition, the invention can ensure that the switching of the proportional valve is all in the effective liquid suction stroke, the pump can not influence the control proportion in the curvilinear motion at any speed, and the problem that the accurate proportion can not be obtained by switching the control division proportion by taking time as an axis is solved.
In addition, the embodiment of the invention is not limited by the fixed number of the mobile phases and is not limited by various proportions (such as extreme proportions of 1% and 99%), and can be separated from the speed curve of the high-pressure pump motor, and has good expansibility.
Fig. 9 is a schematic structural diagram of a flow phase ratio control device according to a ninth embodiment of the present invention, and as shown in fig. 9, the flow phase ratio control device includes: an acquisition module 901, a first calculation module 902, a matching module 903, and a proportional valve 904. Wherein,
the obtaining module 901 is used for obtaining the number and the mixing ratio of the mobile phases to be mixed.
The first calculating module 902 is configured to obtain one or more switching angles according to the mixing ratio and a corresponding relationship between a camshaft angle of the pre-calibrated high-pressure constant flow pump and a liquid suction amount, where the switching angle is a camshaft angle when a switching operation is performed on two mobile phases.
The matching module 903 is used to match the current camshaft angle with one or more switching angles.
The proportional valve 904 is configured to switch the suction object of the high-pressure constant-flow pump from the current mobile phase to a next mobile phase corresponding to a switching angle at which matching is successful according to a matching result.
The proportional valve 904 may adopt a single channel or multiple channels. Those skilled in the art can find relevant information to understand the specific structure of the proportional valve, and the specific structure is not limited herein.
In an optional embodiment, the flow ratio control device may further include a second calculation module (not shown in the figure), configured to use a product of a plunger rod position descending amount corresponding to the camshaft angle and the plunger rod cross-sectional area when the plunger rod is in the descending lift as the liquid suction amount corresponding to the camshaft angle, so as to obtain a correspondence between the camshaft angle and the liquid suction amount of the pre-calibrated high-pressure constant flow pump.
In an alternative embodiment, the flow ratio control apparatus may further include a pressure measurement module and a compensation module (not shown in the figures). The pressure measuring module is used for measuring the liquid pressure in the suction pipeline of the high-pressure constant flow pump; the compensation module is used for compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value if the liquid pressure is not within the preset pressure range.
In an alternative embodiment, the flow phase ratio control apparatus may further include an angle measurement module for measuring a camshaft angle.
In an alternative embodiment, in conjunction with fig. 8, the lowest point of the lift curve of the camshaft is provided with a notch, and the angle measurement module comprises a photoelectric sensor and a processor (not shown in the figure).
The photoelectric sensor comprises a transmitter and a receiver which are fixedly arranged relative to two sides of the camshaft, the transmitter is used for transmitting an optical-electrical signal, and the receiver is used for acquiring the photoelectric signal and transmitting the acquired photoelectric signal to the processor; the processor processes the collected photoelectric signals to obtain the angle of the camshaft.
The embodiment of the invention also provides the high-pressure constant flow pump, which comprises the flow phase ratio control device.
Embodiments of the present invention also provide a computer-readable storage medium, on which a program is stored, and when the program is executed by a processor, the method for controlling the flow phase ratio is implemented.
It should be clear that the embodiments in this specification are described in a progressive manner, and the same or similar parts in the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments. For the device embodiments, reference may be made to the description of the method embodiments in the relevant part. Embodiments of the invention are not limited to the specific steps and structures described above and shown in the drawings. Those skilled in the art may make various changes, modifications and additions to, or change the order between the steps, after appreciating the spirit of the embodiments of the invention. Also, a detailed description of known process techniques is omitted herein for the sake of brevity.
It is to be understood, however, that the embodiments of the invention are not limited to the particular arrangements and instrumentality described above and shown in the drawings. Also, a detailed description of known process techniques is omitted herein for the sake of brevity. In the above embodiments, several specific steps are described and shown as examples. However, the method processes of the embodiments of the present invention are not limited to the specific steps described and illustrated, and those skilled in the art may make various changes, modifications and additions or change the order between the steps after comprehending the spirit of the embodiments of the present invention.
The functional blocks shown in the above-described structural block diagrams may be implemented as hardware, software, firmware, or a combination thereof. When implemented in hardware, it may be, for example, an electronic circuit, an Application Specific Integrated Circuit (ASIC), suitable firmware, plug-in, function card, or the like. When implemented in software, the elements of an embodiment of the invention are the programs or code segments used to perform the required tasks. The program or code segments may be stored in a machine-readable medium or transmitted by a data signal carried in a carrier wave over a transmission medium or a communication link. A "machine-readable medium" may include any medium that can store or transfer information. Examples of a machine-readable medium include electronic circuits, semiconductor memory devices, ROM, flash memory, Erasable ROM (EROM), floppy disks, CD-ROMs, optical disks, hard disks, fiber optic media, Radio Frequency (RF) links, and so forth. The code segments may be downloaded via computer networks such as the internet, intranet, etc.
Embodiments of the present invention may be embodied in other specific forms without departing from its spirit or essential characteristics. For example, the algorithms described in the specific embodiments may be modified without departing from the basic spirit of the embodiments of the present invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the embodiments of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (11)
1. A method for controlling a flow phase ratio, comprising:
obtaining the number and the mixing proportion of the mobile phases to be mixed;
obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the pre-calibrated high-pressure constant flow pump and the liquid absorption amount, wherein the switching angles are the camshaft angles when the two mobile phases are switched;
matching a current camshaft angle with the one or more switching angles;
and switching the suction object of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the successfully matched switching angle according to the matching result.
2. The method according to claim 1, wherein a plunger rod of the high-pressure constant-flow pump is driven by a cam shaft to reciprocate linearly; before obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the high-pressure constant flow pump and the liquid suction amount, the method further comprises the following steps:
and taking the product of the descending amount of the position of the plunger rod corresponding to the angle of the camshaft and the sectional area of the plunger rod when the plunger rod is in the descending lift as the liquid suction amount corresponding to the angle of the camshaft to obtain the corresponding relation between the angle of the camshaft of the pre-calibrated high-pressure constant flow pump and the liquid suction amount.
3. The method according to claim 1, wherein the obtaining one or more switching angles according to the mixing ratio and the corresponding relationship between the camshaft angle and the liquid suction amount of the pre-calibrated high-pressure constant flow pump comprises:
taking the angle interval of the camshaft when the liquid absorption amount in the stroke cycle is not 0 as an absorption interval;
dividing the suction interval by using the mixing proportion to obtain suction subintervals corresponding to the flows;
and taking the camshaft angle corresponding to the node between the adjacent suction subintervals as the switching angle of the two mobile phases corresponding to the adjacent suction subintervals.
4. The method according to claim 1, wherein after the switching the suction object of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle at which the matching is successful according to the matching result, the method further comprises:
measuring the liquid pressure in the suction pipeline of the high-pressure constant flow pump;
and if the liquid pressure is not within the preset pressure range, compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value.
5. A flow phase ratio control apparatus, comprising:
the acquisition module is used for acquiring the number and the mixing proportion of the mobile phases to be mixed;
the first calculation module is used for obtaining one or more switching angles according to the mixing proportion and the corresponding relation between the camshaft angle of the pre-calibrated high-pressure constant flow pump and the liquid absorption amount, wherein the switching angles are the camshaft angles when the two mobile phases are switched;
the matching module is used for matching the current camshaft angle with the one or more switching angles;
and the proportional valve is used for switching the suction object of the high-pressure constant flow pump from the current mobile phase to the next mobile phase corresponding to the switching angle of successful matching according to the matching result.
6. The device according to claim 5, wherein the plunger rod of the high-pressure constant-flow pump is driven by a cam shaft to do linear reciprocating motion; the device also comprises a second calculation module, which is used for taking the product of the plunger rod position descending amount corresponding to the camshaft angle and the plunger rod sectional area when the plunger rod is in the descending lift as the liquid suction amount corresponding to the camshaft angle, so as to obtain the corresponding relation between the camshaft angle and the liquid suction amount of the pre-calibrated high-pressure constant flow pump.
7. The apparatus of claim 5, further comprising:
the pressure measuring module is used for measuring the liquid pressure in the suction pipeline of the high-pressure constant flow pump;
and the compensation module is used for compensating the rotating speed of the high-pressure constant flow pump according to the measured liquid pressure value if the liquid pressure is not within the preset pressure range.
8. The apparatus of claim 5, further comprising: and the angle measuring module is used for measuring the angle of the camshaft.
9. The device of claim 8, wherein a notch is arranged at a lowest point position of a lift curve of the camshaft, and the angle measurement module comprises a photoelectric sensor and a processor; wherein,
the photoelectric sensor comprises a transmitter and a receiver which are fixedly arranged relative to two sides of the cam shaft, the transmitter is used for transmitting an optical-electrical signal, and the receiver is used for collecting the photoelectric signal and transmitting the collected photoelectric signal to the processor;
the processor obtains the angle of the camshaft according to the collected photoelectric signals.
10. A high-pressure constant flow pump comprising the flow ratio control device according to any one of claims 5 to 9.
11. A computer-readable storage medium on which a program is stored, the program implementing the mobile phase proportion control method according to any one of claims 1 to 5 when executed by a processor.
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| JP2001041128A (en) * | 1999-07-28 | 2001-02-13 | Toyota Motor Corp | High pressure fuel pump |
| JP2005282517A (en) * | 2004-03-30 | 2005-10-13 | Shimadzu Corp | Liquid feeding device |
| CN100424343C (en) * | 2006-06-22 | 2008-10-08 | 上海交通大学 | Method for Determining the Cam Profile Shape of Non-Shock Constant Flow Double Piston Pump |
| US7444989B2 (en) * | 2006-11-27 | 2008-11-04 | Caterpillar Inc. | Opposed pumping load high pressure common rail fuel pump |
| CN205714626U (en) * | 2016-03-28 | 2016-11-23 | 大连赛恩仪表股份有限公司 | Integral modular high pressure constant flow pump |
| CN107387400B (en) * | 2017-08-08 | 2020-08-21 | 江苏同济分析仪器有限公司 | Method for assembling plunger mechanism of high-pressure infusion pump of liquid chromatograph |
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