CN102462532B - Conduit system with label testing and ablation functions in blood vessels - Google Patents
Conduit system with label testing and ablation functions in blood vessels Download PDFInfo
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- CN102462532B CN102462532B CN 201110327772 CN201110327772A CN102462532B CN 102462532 B CN102462532 B CN 102462532B CN 201110327772 CN201110327772 CN 201110327772 CN 201110327772 A CN201110327772 A CN 201110327772A CN 102462532 B CN102462532 B CN 102462532B
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- conduit
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- 238000002679 ablation Methods 0.000 title claims abstract description 30
- 210000004204 blood vessel Anatomy 0.000 title abstract description 12
- 238000013507 mapping Methods 0.000 claims description 28
- 208000031481 Pathologic Constriction Diseases 0.000 claims description 2
- 210000001215 vagina Anatomy 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 239000011664 nicotinic acid Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 abstract description 12
- 239000002184 metal Substances 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 10
- 210000002254 renal artery Anatomy 0.000 abstract description 10
- 230000002889 sympathetic effect Effects 0.000 abstract description 10
- 238000011282 treatment Methods 0.000 abstract description 9
- 210000005036 nerve Anatomy 0.000 abstract description 8
- 238000007674 radiofrequency ablation Methods 0.000 abstract description 2
- 239000008280 blood Substances 0.000 description 15
- 239000000155 melt Substances 0.000 description 9
- 206010020772 Hypertension Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 206010038419 Renal colic Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000013153 catheter ablation Methods 0.000 description 2
- 208000013403 hyperactivity Diseases 0.000 description 2
- 230000030214 innervation Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 230000001053 orthosympathetic effect Effects 0.000 description 2
- 230000008660 renal denervation Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
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- 206010019280 Heart failures Diseases 0.000 description 1
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- 208000035965 Postoperative Complications Diseases 0.000 description 1
- 208000004531 Renal Artery Obstruction Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010038378 Renal artery stenosis Diseases 0.000 description 1
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Abstract
The invention discloses a conduit with electric label testing and radiofrequency ablation functions in blood vessels, which is divided into three parts: (1), the pointed part of the conduit can be adhered to a plurality of metal straps; (2), the body part of the conduit is composed of the conduit sheath and internal cores; and (3), the rear part of the conduit is provided with an operational handle. When the metal straps at the pointed part of the conduit are not opened, the conduit is cylindrical so as to enter blood vessels conveniently; when the sheath is fixed and the internal cores are drawn back, the metal straps at the pointed part of the conduit are opened to be adhered to the inner walls of the blood vessels; and the conduit has electric label testing and ablation functions. When renal artery sympathetic nerves are exciting, one or more metal straps at the corresponding part can be tested; and the corresponding metal straps are ablated. After finishing ablating the metal straps, the metal straps are tested so as to observe the ablation effect; and if the ablation is incomplete, the metal straps are repeatedly operated until having exact effect. The conduit system provided in the invention can improve curative effect and reduce treatment complications and operation risk.
Description
Affiliated technical field
This invention is used for the interior electrical mapping of blood vessel and the radio-frequency (RF) ablation of medical field.
Technical background
Through conduit Renal denervation (Transcatheter Renal Denervation, TRenD) or kidney to go sympathetic nerve (Renal Sympathetic Denervation, RSD) treatment be the present up-to-date hypertensive method of a kind of non-medicine interventional therapy in the world.It comes from the beginning of this century several American physician in treatment during an intractable renal colic patient, in the situation that the whole bag of tricks is failed to respond to any medical treatment, adopted the method for CT guiding lower benefit caine hilus renalis district sealing, the result is surprisingly found out that patient not only renal colic is alleviated simultaneously also with the reduction of blood pressure and increasing of urine amount.These doctors with scientific research brains are studied in detail this strange phenomenon.Pass through searching document, they found as far back as nineteen fifty-three, American German doctor Smithwick just adopts surgical operation to cut off the method treatment of visceral nerve to 1226 intractable hypertension patients, through following up a case by regular visits to of 5-14, patient's hypertension all obtains good control, because postoperative complication is more and the good efficacy of antihypertensive agent, this operation was eliminated gradually afterwards.The pioneers of these TRenD treatments find through research, nerve around the renal artery only has sympathetic nerve, and orthosympathetic the putting forth energy property that is extremely delighted (Sympathetic Hyperactivity) is relevant with numerous disease, known pathological changes comprises the arrhythmia of hypertension, renal failure, diabetes, heart failure and some type at present, so again this type of disease is referred to as at present sympathetic nerve the putting forth energy property diseases related (Sympathetic Hyperactivity Related Diseases, SHRD) that is extremely delighted.Can so, do not adopt operation and radio frequency is eliminated orthosympathetic the putting forth energy property that is extremely delighted in the renal artery blood vessel whether also reach the same effect of operation? through research repeatedly, conclusion is sure.2009 world-renowned medical journal " lancet " delivered with the research paper headed by the Australian doctor Krum, having confirmed to get involved in the renal artery radio frequency method is effective to treatment hypertension.Therefore the perpetrator Mark Gelfand of this technology and Howard R Levin win 2011 annual U.S. Edison invented silver medals.This patent inventor once had the honor to cooperate to carry out in 4 years clinical research with two scientists, had still kept good relation with them so far.
JIUYUE in 2011 24 days held Asia-Pacific TRenD meeting in Hong Kong Marriott Hotel, put on display at present unique in the world commercial TRenD ablation catheter in the meeting---the last word SymplicityR of Medtronic Inc. and on-the-spot demonstration 3 example operations (live in conference by transmission of video).The SymplicityR conduit is a solid conduit, push rod on the current rear promotion control handle, catheter tip can be become by linear " J " shape, so that catheter tip tightly facing to arteriorenal medial wall in order to the teleneuron of giving of blood vessel wall is carried out point-like and melts, usually 6-8 point need to be melted, just therapeutic effect can be reached.This ablation catheter and method have following deficiency: (1) point-like melts and can't guarantee that this point is the point of sympathetic innervation, therefore will do 6-8 point, and a shot at a bird shoot bird to be similar to sand-blasting gun; By the position of X-ray examination indirect observation conduit, therefore can't guarantee that 8 ablation points are even range distribution at Wall of Artery when (2) treatment operates, might on same point, repeatedly melt to have the danger of vascular puncture; (3) ablation points is more causes that easily cicatrix is too much on the blood vessel wall, causes renal artery stenosis; (4) position at sympathetic nerve place on can't mapping renal artery wall, thus also can't in operation, detect the kidney sympathetic nerve whether melt to or melt whether fully.Often need to judge the effect that melts by postoperative clinical examination that if poor effect, patient also will accept for the second time operation.In this case, the conduit of a better efficacy of invention is exactly the task of top priority of TRenD Therapeutic Method.
Summary of the invention
For above shortcoming, the invention provides electrical mapping and radio frequency ablation catheter, accurately mapping sympathetic innervation point in a kind of blood vessel, and it is carried out precision ablation, each mapping ablation points is evenly distributed, can operate multiple spot simultaneously, after melting again mapping judge ablation effect.
The technical solution adopted for the present invention to solve the technical problems is: patient just can know length and the diameter of renal artery blood vessel behind renal arteriography, the mapping ablation catheter is in seal wire inserts corresponding renal artery, and bonding jumper to the corresponding diameter (showing at diameter labelling window) of opening catheter tip makes it be close to the renal artery inwall.When the renal artery sympathetic activation, one (several) root bonding jumper of corresponding site will measure, and melts corresponding bonding jumper and gets final product.Melt to do again after complete and detect the effect that melts with observation, if melt not exclusively again repetitive operation until definite effect.
The invention has the beneficial effects as follows: (1) guarantees that catheter ablation point can be evenly distributed in blood vessel; (2) under the guiding of mapping, the point of guaranteeing catheter ablation is the position of SNE domination, has reduced the drawback that blindly melts; (3) after melting, again detect, can guarantee the effect that melts; (4) because mapping is arranged, so the energy that melts can be as far as possible little, can avoid to greatest extent the danger of vascular puncture; Direction with renal artery blood flow when (5) the conduit bonding jumper is opened is consistent, and blood flow can circulate between the bonding jumper of opening, and is little for impact on the blood of kidney, the infringement of having avoided kidney to cause because of ischemia at normal temperatures; (6) because can precision ablation, therefore can reduce to greatest extent the complication of this treatment and reduce the risk of operation.
Description of drawings
The mapping ablation catheter struts the engineering profile of rear the first form and structure in Fig. 1-blood vessel.
The mapping ablation catheter struts the engineering profile of rear the second form and structure in Fig. 2-blood vessel.
The engineering profile of the third form and structure after the mapping ablation catheter struts in Fig. 3-blood vessel.
The mapping ablation catheter struts the engineering profile of rear the 4th kind of form and structure in Fig. 4-blood vessel.
The mapping ablation catheter struts the engineering profile of rear the 5th kind of form and structure in Fig. 5-blood vessel.
The initial condition that the mapping ablation catheter does not strut in Fig. 6-blood vessel.
The handle portion of mapping ablation catheter system in Fig. 7-blood vessel.
1. catheter jackets among the figure; 2. catheter tip bonding jumper; 3. conduit inner core; 4. handle; 5. spiral button; 6. diameter mark window;
7. wire.
The specific embodiment
The mapping ablation catheter struts the engineering profile of rear the first form and structure in Fig. 1-blood vessel: assume diamond in shape after catheter tip metal (2) bar struts; Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).When inner core (3) when drawing back, be fixed on the straight shape bonding jumper of catheter jacket (1) and form tension force, catheter tip bonding jumper (2) struts.
The mapping ablation catheter struts the engineering profile of rear the second form and structure in Fig. 2-blood vessel: be pre-large post-small taper shape after catheter tip metal (2) bar struts; Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).When inner core (3) when drawing back, be fixed on the straight shape bonding jumper of catheter jacket (1) and form tension force, catheter tip bonding jumper (2) struts.
The engineering profile of the third form and structure after the mapping ablation catheter struts in Fig. 3-blood vessel: be pre-small post-large taper shape after catheter tip metal (2) bar struts; Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).When inner core (3) when drawing back, be fixed on the straight shape bonding jumper of catheter jacket (1) and form tension force, catheter tip bonding jumper (2) struts.
The mapping ablation catheter struts the engineering profile of rear the 4th kind of form and structure in Fig. 4-blood vessel: catheter tip metal (2) bar struts rear rectangular, but bonding jumper and conduit longitudinal axis angle at 45 °, so be referred to as the spiral rectangle.Such 8 bonding jumpers just can cover the inwall of blood vessel fully.If 4 or 6 bonding jumpers, then bonding jumper becomes 90 ° or 60 ° of angles with the conduit longitudinal axis, can cover equally the inwall of blood vessel fully.Bonding jumper and the conduit longitudinal axis are that 0 °～90 ° angles can be selected; Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).When inner core (3) when drawing back, be fixed on the straight shape bonding jumper of catheter jacket (1) and form tension force, catheter tip bonding jumper (2) struts.
The engineering profile of the 5th kind of form and structure after the mapping ablation catheter struts in Fig. 5-blood vessel: catheter tip bonding jumper (2) struts rear rectangular, and bonding jumper is parallel with the conduit longitudinal axis, i.e. 0 ° of angle is so be referred to as horizontal rectangular; Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).When inner core (3) when retreating, be fixed on the straight shape bonding jumper of catheter jacket (1) and form tension force, catheter tip bonding jumper (2) struts.
The initial condition that the mapping ablation catheter does not strut in Fig. 6-blood vessel, conduit bonding jumper (2) is cylindric when not opening, to make things convenient in the intravasation.Bonding jumper (2) front end links to each other with inner core (3); Bonding jumper (2) rear end links to each other with overcoat (1).
The handle portion of mapping ablation catheter system in Fig. 7-blood vessel: handle (4) is that circle or oval are dominated by hand with the handled easily person, and its inside has conduit inner core (3) to pass through.Spiral button (5) is positioned on the handle (4), and the outer ring-like stricture of vagina of the female thread that it is inner and inner core (3) interlocks, and when rotating spiral button (5), can make inner core (3) mobile forward or backward; Handle the big or small folding of tip bonding jumper (2).Handle (4) at spiral button (5) rear has a bright zone, in diameter mark window (6) is arranged, can show the diameter that catheter tip bonding jumper (2) opens, the end of handle (4) has wire (7) to draw, wherein there is wire to link to each other respectively with each root bonding jumper in the catheter tip bonding jumper (2), wire melts machine with outside mapping and is connected, in order to the bio electricity mapping of each bonding jumper and melt.
Claims (9)
1. an Endovascular has the conduit system of electrical mapping and ablation functionality simultaneously, it is characterized in that being divided into three parts: the bonding jumper that (1) catheter tip can opening and closing; (2) body that is consisted of by catheter jacket and conduit inner core; (3) handle portion at rear portion; Described handle portion is divided into (1) handle; (2) spiral button; (3) diameter mark window.
2. conduit system according to claim 1 is characterized in that catheter tip is made of miniature described bonding jumper, and every bonding jumper and the conduit longitudinal axis are with 0
o～90
oThe angle arc be centered around around the conduit inner core, conduit is a straight tube-like when not strutting closure state.
3. conduit system according to claim 1, the near-end that it is characterized in that the catheter tip bonding jumper links to each other with catheter jacket, and the bonding jumper far-end links to each other with the conduit inner core, by the mutual size of motor control catheter tip bonding jumper folding longitudinally between conduit inner core and the catheter jacket.
4. conduit system according to claim 1, it is characterized in that described catheter tip bonding jumper is different according to the intensity that its front and back end is connected to catheter jacket and bonding jumper different parts different with the position of conduit inner core own, bonding jumper struts one of following 5 kinds of shapes of rear formation: 1. rhombus; 2. pre-large post-small taper shape; 3. pre-small post-large taper shape; 4. spiral rectangle; 5. horizontal rectangular.
5. conduit system according to claim 1, it is characterized in that every bonding jumper of described catheter tip all has continuous wire to lead to the rear portion of catheter handle part in the overcoat wall of conduit, be combined into a wire, and link to each other with corresponding mapping instrument or ablatograph.
6. conduit system according to claim 1, it is characterized in that described conduit inner core is the conduit of a hollow in the catheter jacket, its backward, during to front slide so that the bonding jumper of catheter tip struts or closed, the conduit inner core is convenient to passing through of seal wire and contrast agent simultaneously.
7. conduit system according to claim 1, it is characterized in that described handle is the bionic oval structure of human body, its front portion links to each other with the outer wall of conduit, and described spiral button is housed, inside has cavity can pass through the conduit inner core, and the conduit inner core passes through the cavity of the handle rear portion from handle.
8. conduit system according to claim 1, it is characterized in that described spiral button is positioned on the described handle, the outer ring-like stricture of vagina of the female thread that it is inner and conduit inner core interlocks, when rotating the spiral button, can make the conduit inner core mobile forward or backward, the big or small folding of the most advanced and sophisticated bonding jumper of control lead.
9. conduit system according to claim 1 is characterized in that described diameter mark window is the transparent diameter mark window of rectangle, is arranged on the top of the rear handle of described spiral button, shows the diameter that the catheter tip bonding jumper struts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110327772 CN102462532B (en) | 2011-10-25 | 2011-10-25 | Conduit system with label testing and ablation functions in blood vessels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110327772 CN102462532B (en) | 2011-10-25 | 2011-10-25 | Conduit system with label testing and ablation functions in blood vessels |
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| Publication Number | Publication Date |
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| CN102462532A CN102462532A (en) | 2012-05-23 |
| CN102462532B true CN102462532B (en) | 2013-03-13 |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102860867B (en) * | 2012-10-15 | 2014-11-05 | 陈平根 | Multi-electrode radio frequency ablation catheter and design method thereof |
| CN102871727B (en) * | 2012-10-30 | 2015-07-08 | 陈平根 | Multipolar radiofrequency ablation catheter which is applicable to being used in renal artery vessels |
| MY179432A (en) | 2013-02-07 | 2020-11-06 | Shanghai Golden Leaf Med Tec Co Ltd | Radio frequency ablation method, system and radio frequency ablation device thereof |
| CN103505798B (en) * | 2013-09-30 | 2015-09-09 | 上海魅丽纬叶医疗科技有限公司 | The fluted ablation catheter in surface |
| CN103271765B (en) * | 2013-02-07 | 2016-05-11 | 上海魅丽纬叶医疗科技有限公司 | Wear the neural ablation catheter of wall, Apparatus for () and method therefor through chamber |
| CN106901831A (en) * | 2017-03-23 | 2017-06-30 | 深圳市惠泰医疗器械有限公司 | The arteria renalis stimulates ablating electrode conduit |
| CN107468331A (en) * | 2017-08-21 | 2017-12-15 | 常州朗合医疗器械有限公司 | Radio frequency ablation catheter and system |
| CN114748153B (en) * | 2021-01-08 | 2025-10-14 | 北京迈迪顶峰医疗科技股份有限公司 | Ablation devices and radiofrequency ablation equipment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1765151A2 (en) * | 2004-05-17 | 2007-03-28 | C.R.Bard, Inc. | Mapping and ablation method for the treatment of ventricular tachycardia |
| CN101309651B (en) * | 2005-06-20 | 2011-12-07 | 麦德托尼克消融前沿有限公司 | Ablation catheter |
| CA2781951A1 (en) * | 2009-11-13 | 2011-05-19 | St. Jude Medical, Inc. | Assembly of staggered ablation elements |
| CN102198015B (en) * | 2011-05-03 | 2013-11-06 | 上海微创电生理医疗科技有限公司 | Retractable spiral laminar ring type electrode catheter |
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