AU2002249275A1 - Oxo azabicyclic compounds - Google Patents

Oxo azabicyclic compounds

Info

Publication number: AU2002249275A1
Authority: AU; Australia
Prior art keywords: oxo; azabicyclic compounds; azabicyclic; compounds; oxo azabicyclic
Prior art date: 2002-03-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002249275A

Inventor

Bernard Gaudilliere

Henry Jacobelli

Catherine Kostlan

Jack Li

Wen-Song Yue

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Warner Lambert Co LLC

Original Assignee

Warner Lambert Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-08

Filing date

2002-03-08

Publication date

2003-09-22

2002-03-08 Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC

2003-09-22 Publication of AU2002249275A1 publication Critical patent/AU2002249275A1/en

Status Abandoned legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AU2002249275A 2002-03-08 2002-03-08 Oxo azabicyclic compounds Abandoned AU2002249275A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2002/003240 WO2003076416A1 (en)	2002-03-08	2002-03-08	Oxo azabicyclic compounds

Publications (1)

Publication Number	Publication Date
AU2002249275A1 true AU2002249275A1 (en)	2003-09-22

Family

ID=27798761

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU2002249275A Abandoned AU2002249275A1 (en)	2002-03-08	2002-03-08	Oxo azabicyclic compounds
AU2003212307A Abandoned AU2003212307A1 (en)	2002-03-08	2003-03-06	Oxo-azabicyclic compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2003212307A Abandoned AU2003212307A1 (en)	2002-03-08	2003-03-06	Oxo-azabicyclic compounds

Country Status (25)

Country	Link
EP (1)	EP1492775A2 (en)
JP (1)	JP2005526070A (en)
KR (1)	KR20040095270A (en)
CN (1)	CN1738806A (en)
AP (1)	AP2004003125A0 (en)
AR (1)	AR039562A1 (en)
AU (2)	AU2002249275A1 (en)
BR (1)	BR0308280A (en)
CA (1)	CA2478706A1 (en)
CO (1)	CO5601020A2 (en)
EA (1)	EA200401053A1 (en)
EC (1)	ECSP045278A (en)
IL (1)	IL163818A0 (en)
IS (1)	IS7414A (en)
MA (1)	MA27183A1 (en)
MX (1)	MXPA04008681A (en)
NO (1)	NO20044041L (en)
OA (1)	OA12782A (en)
PA (1)	PA8568501A1 (en)
PE (1)	PE20031018A1 (en)
PL (1)	PL372622A1 (en)
SV (1)	SV2003001495A (en)
TN (1)	TNSN04169A1 (en)
UY (1)	UY27700A1 (en)
WO (2)	WO2003076416A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PA8539501A1 (en)	2001-02-14	2002-09-30	Warner Lambert Co	TRIAZOLO COMPOUNDS AS MMP INHIBITORS
US6962922B2 (en)	2001-10-12	2005-11-08	Warner-Lambert Company Llc	Alkynylated quinazoline compounds
US6894057B2 (en)	2002-03-08	2005-05-17	Warner-Lambert Company	Oxo-azabicyclic compounds
AU2003249539A1 (en) *	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
EP1539709A1 (en)	2002-08-13	2005-06-15	Warner-Lambert Company LLC	Azaisoquinoline derivatives as matrix metalloproteinase inhibitors
WO2004014378A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	3-isoquinolinone derivatives as matrix metalloproteinase inhiitors
WO2004014892A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Monocyclic derivatives as matrix metalloproteinase inhibitors
JP2005539020A (en)	2002-08-13	2005-12-22	ワーナー−ランバートカンパニーリミティドライアビリティーカンパニー	Chromone derivatives as matrix metalloproteinase inhibitors
WO2004014375A2 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Fused bicyclic metalloproteinase inhibitors
PA8578101A1 (en)	2002-08-13	2004-05-07	Warner Lambert Co	HETEROBIARILO DERIVATIVES AS METALOPROTEINASE IN MATRIX INHIBITORS
AU2003250470A1 (en)	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Pyrimidinone fused bicyclic metalloproteinase inhibitors
MXPA05001783A (en)	2002-08-13	2005-04-25	Warner Lambert Co	Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors.
WO2004014909A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors
WO2005016926A1 (en) *	2003-08-19	2005-02-24	Warner-Lambert Company Llc	Pyrido [3,4-d] pyrimidine derivatives as matrix metalloproteinase-13 inhibitors
DE10360835A1 (en) *	2003-12-23	2005-07-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New bicyclic imidazole derivatives are dipeptidylpeptidase-IV inhibitors useful to treat e.g. arthritis, obesity, allograft transplantation and calcitonin-induced osteoporosis
BRPI0510305A (en) *	2004-04-30	2007-10-02	Takeda Pharmaceutical	compound or a salt thereof, prodrug or a salt thereof, pharmaceutical agent, method of producing the compound or a salt thereof, matrix metalloproteinase inhibitor or a salt thereof or a prodrug thereof, method of inhibiting a metalloproteinase matrix, and use of a compound or salt thereof or a prodrug thereof
CA2568756A1 (en) *	2004-06-15	2005-12-29	Astrazeneca Ab	Substituted quinazolones as anti-cancer agents
CN101522676A (en)	2006-10-05	2009-09-02	Cv医药有限公司	Bicyclic nitrogen-containing heterocyclic compounds as stearoyl-CoA dehydrogenase inhibitors
WO2012052451A1 (en)	2010-10-18	2012-04-26	Merz Pharma Gmbh & Co. Kgaa	Metabotropic glutamate receptor modulators
CN103524431B (en) *	2013-09-24	2016-01-13	西安交通大学	3-benzyl-4-quianzolinones and synthetic method thereof and application
JO3512B1 (en)	2014-03-26	2020-07-05	Astex Therapeutics Ltd	Quinoxaline derivatives useful as fgfr kinase modulators
AU2016328693B2 (en)	2015-09-23	2021-03-11	Janssen Pharmaceutica Nv	Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer
DK3353177T3 (en)	2015-09-23	2020-08-24	Janssen Pharmaceutica Nv	TRICYCLIC HETEROCYCLES FOR CANCER TREATMENT
FR3046793B1 (en) *	2016-01-14	2018-01-05	Les Laboratoires Servier	NOVEL PHOSPHINAN DERIVATIVES AND AZAPHOSPHINANES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9714222A (en) *	1996-12-17	2000-04-18	Du Pont	Method for controlling plant diseases
PA8539401A1 (en) *	2001-02-14	2002-10-28	Warner Lambert Co	QUINAZOLINAS AS INHIBITORS OF MMP-13
PA8539301A1 (en) *	2001-02-14	2002-09-30	Warner Lambert Co	INHIBITORS OF THE METALOPROTEINASE OF THE MATRIX

2002
- 2002-03-08 AU AU2002249275A patent/AU2002249275A1/en not_active Abandoned
- 2002-03-08 WO PCT/EP2002/003240 patent/WO2003076416A1/en not_active Ceased
2003
- 2003-03-04 SV SV2003001495A patent/SV2003001495A/en not_active Application Discontinuation
- 2003-03-06 PE PE2003000218A patent/PE20031018A1/en not_active Application Discontinuation
- 2003-03-06 EP EP03708181A patent/EP1492775A2/en not_active Withdrawn
- 2003-03-06 IL IL16381803A patent/IL163818A0/en unknown
- 2003-03-06 AP APAP/P/2004/003125A patent/AP2004003125A0/en unknown
- 2003-03-06 KR KR10-2004-7013994A patent/KR20040095270A/en not_active Ceased
- 2003-03-06 MX MXPA04008681A patent/MXPA04008681A/en unknown
- 2003-03-06 WO PCT/EP2003/002277 patent/WO2003076417A2/en not_active Ceased
- 2003-03-06 EA EA200401053A patent/EA200401053A1/en unknown
- 2003-03-06 JP JP2003574636A patent/JP2005526070A/en not_active Withdrawn
- 2003-03-06 CN CNA038048752A patent/CN1738806A/en active Pending
- 2003-03-06 AU AU2003212307A patent/AU2003212307A1/en not_active Abandoned
- 2003-03-06 AR ARP030100749A patent/AR039562A1/en not_active Application Discontinuation
- 2003-03-06 CA CA002478706A patent/CA2478706A1/en not_active Abandoned
- 2003-03-06 UY UY27700A patent/UY27700A1/en not_active Application Discontinuation
- 2003-03-06 PL PL03372622A patent/PL372622A1/en not_active Application Discontinuation
- 2003-03-06 PA PA20038568501A patent/PA8568501A1/en unknown
- 2003-03-06 BR BR0308280-6A patent/BR0308280A/en not_active IP Right Cessation
- 2003-03-06 OA OA1200400234A patent/OA12782A/en unknown
2004
- 2004-08-19 IS IS7414A patent/IS7414A/en unknown
- 2004-08-25 CO CO04082792A patent/CO5601020A2/en not_active Application Discontinuation
- 2004-08-31 MA MA27842A patent/MA27183A1/en unknown
- 2004-09-03 EC EC2004005278A patent/ECSP045278A/en unknown
- 2004-09-03 TN TNP2004000169A patent/TNSN04169A1/en unknown
- 2004-09-24 NO NO20044041A patent/NO20044041L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2003076417A2 (en)	2003-09-18
BR0308280A (en)	2004-12-28
EP1492775A2 (en)	2005-01-05
JP2005526070A (en)	2005-09-02
AU2003212307A1 (en)	2003-09-22
EA200401053A1 (en)	2005-04-28
CO5601020A2 (en)	2006-01-31
WO2003076417A3 (en)	2003-11-13
KR20040095270A (en)	2004-11-12
MXPA04008681A (en)	2004-12-06
TNSN04169A1 (en)	2007-03-12
PL372622A1 (en)	2005-07-25
AP2004003125A0 (en)	2004-09-30
CA2478706A1 (en)	2003-09-18
NO20044041L (en)	2004-10-07
AR039562A1 (en)	2005-02-23
IL163818A0 (en)	2005-12-18
PA8568501A1 (en)	2003-12-19
ECSP045278A (en)	2004-10-26
OA12782A (en)	2006-07-10
CN1738806A (en)	2006-02-22
UY27700A1 (en)	2003-10-31
PE20031018A1 (en)	2004-01-09
IS7414A (en)	2004-08-19
MA27183A1 (en)	2005-01-03
WO2003076416A1 (en)	2003-09-18
SV2003001495A (en)	2003-11-04

Legal Events

Date	Code	Title	Description
2004-11-25	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase

Publication	Publication Date	Title
AU2002249275A1 (en)	2003-09-22	Oxo azabicyclic compounds
AU2003266949A1 (en)	2004-01-19	Compounds
AU2003221098A1 (en)	2003-10-08	Oligofluorenylene compounds
AU2003248588A1 (en)	2004-03-03	Substituted pyrrolopyridines
AU2003262244A1 (en)	2004-03-03	Nitrogen-containing compounds
AU2003250541A1 (en)	2004-02-23	Anthropometry-based skeleton fitting
AU2003265509A1 (en)	2004-03-03	Neurostimulator
AU2003279366A1 (en)	2004-06-07	Novel compounds
AU2003216859A1 (en)	2003-10-08	Amidoacetonitrile compounds
AU2003290818A1 (en)	2004-06-03	Topoisomerase-targeting agents
AU2003297381A1 (en)	2004-07-22	Attachment means
AU2003302624A1 (en)	2004-06-23	Silicon compounds
AU2002951868A0 (en)	2002-10-24	Compound i
AU2003284831A1 (en)	2004-06-18	Freight-moving vehicle
AU2003292667A1 (en)	2004-07-22	Benzocycloheptapyridine compounds
AU2003240837A1 (en)	2003-11-11	Floorboard
AU2003251259A1 (en)	2004-02-09	Novel compounds
AU2003255322A1 (en)	2004-02-23	Compounds
AU2003275480A1 (en)	2004-05-04	Compounds
AU2003276788A1 (en)	2004-05-13	Vehicle
AU2003273023A1 (en)	2004-05-04	Parts for vehicle
AU2003226541A1 (en)	2003-11-03	Novel compounds
HK1094164A (en)	2007-03-23	Heteroaryl-hydrazone compounds
HK1082920A (en)	2006-06-23	Indolizine compounds
HK1082763A (en)	2006-06-16	Novel compounds