ATE225847T1 - Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen - Google Patents
Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellenInfo
- Publication number
- ATE225847T1 ATE225847T1 AT93908270T AT93908270T ATE225847T1 AT E225847 T1 ATE225847 T1 AT E225847T1 AT 93908270 T AT93908270 T AT 93908270T AT 93908270 T AT93908270 T AT 93908270T AT E225847 T1 ATE225847 T1 AT E225847T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- compositions
- maintaining
- methods
- devices
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 238000012258 culturing Methods 0.000 title 1
- 230000001464 adherent effect Effects 0.000 abstract 2
- 239000003102 growth factor Substances 0.000 abstract 2
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 2
- 210000002536 stromal cell Anatomy 0.000 abstract 2
- 230000029142 excretion Effects 0.000 abstract 1
- 230000003394 haemopoietic effect Effects 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84596992A | 1992-03-04 | 1992-03-04 | |
| PCT/US1993/001803 WO1993018132A1 (en) | 1992-03-04 | 1993-03-04 | Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE225847T1 true ATE225847T1 (de) | 2002-10-15 |
Family
ID=25296563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93908270T ATE225847T1 (de) | 1992-03-04 | 1993-03-04 | Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0629236B1 (de) |
| JP (1) | JPH07504570A (de) |
| KR (1) | KR100271284B1 (de) |
| AT (1) | ATE225847T1 (de) |
| AU (1) | AU685743B2 (de) |
| CA (1) | CA2131385C (de) |
| DE (1) | DE69332374T2 (de) |
| WO (1) | WO1993018132A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6242417B1 (en) | 1994-03-08 | 2001-06-05 | Somatogen, Inc. | Stabilized compositions containing hemoglobin |
| US5631219A (en) * | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
| EP0698085A4 (de) * | 1994-03-11 | 1996-08-21 | Baxter Int | Durchfluss-bioreaktor mit rillen zur zurückhaltung von zellen |
| US5792603A (en) * | 1995-04-27 | 1998-08-11 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts |
| US5846828A (en) * | 1995-06-07 | 1998-12-08 | Advanced Tissue Sciences | Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments |
| US6121042A (en) * | 1995-04-27 | 2000-09-19 | Advanced Tissue Sciences, Inc. | Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs |
| AU5931896A (en) * | 1995-06-07 | 1996-12-30 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs |
| US5688687A (en) * | 1995-06-07 | 1997-11-18 | Aastrom Biosciences, Inc. | Bioreactor for mammalian cell growth and maintenance |
| US5843766A (en) * | 1995-06-07 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Apparatus for the growth and packaging of three dimensional tissue cultures |
| US5763267A (en) * | 1996-04-16 | 1998-06-09 | Advanced Tissue Sciences | Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures |
| WO1998050522A1 (en) * | 1997-05-07 | 1998-11-12 | Baxter International Inc. | Method and apparatus for high volume production of viral particles |
| FR2771421B1 (fr) * | 1997-11-27 | 2001-05-04 | Bertin & Cie | Dispositif d'amplification de cellules hematopoietiques et ses applications |
| NL1017973C2 (nl) * | 2000-05-10 | 2002-11-08 | Tristem Trading Cyprus Ltd | Inrichting. |
| AU3039602A (en) * | 2000-10-06 | 2002-04-29 | Michael B Dancu | System and method to simulate hemodynamics |
| DE10128810B4 (de) * | 2001-06-18 | 2013-11-07 | Pan-Biotech Gmbh | Einrichtung zur Kultivierung von Zellen, insbesondere menschlicher oder tierischer Zellen |
| WO2003087292A2 (en) * | 2002-04-08 | 2003-10-23 | Millenium Biologix Inc. | Automated tissue engineering system |
| DE10223536A1 (de) * | 2002-05-27 | 2003-12-18 | J Hinrich Peters | Verfahren zur Trennung nicht-adhärenter Zellen von adhärenten Zellen |
| ES2295465T3 (es) | 2002-09-16 | 2008-04-16 | Pan-Biotech Gmbh | Procedimiento para el cultivo de celulas, en especial de celulas humanas o de animales. |
| CN1993460A (zh) * | 2004-07-12 | 2007-07-04 | 索林集团意大利有限公司 | 用于培养人细胞的装置和方法 |
| US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
| WO2008028241A1 (en) * | 2006-09-06 | 2008-03-13 | The University Of Queensland | Microbioreactor |
| WO2009104296A1 (ja) * | 2008-02-22 | 2009-08-27 | コバレントマテリアル株式会社 | 細胞培養モジュール |
| US8586360B2 (en) * | 2009-07-02 | 2013-11-19 | Anthrogenesis Corporation | Method of producing erythrocytes without feeder cells |
| GB0914195D0 (en) * | 2009-08-13 | 2009-09-16 | Plasticell Ltd | Vessel for culturing cells |
| AU2012271412A1 (en) * | 2011-06-15 | 2014-01-09 | Jeffrey T. Borenstein | Device and method for culturing cells in a biomimetic environment |
| EP2720731B1 (de) | 2011-06-15 | 2020-11-18 | The Charles Stark Draper Laboratory, Inc. | Systeme, verfahren und vorrichtung in zusammenhang mit einer biomimetischen zell-nephroneinheit |
| HK1202581A1 (en) | 2012-02-13 | 2015-10-02 | Gamida-Cell Ltd. | Mesenchymal stem cells conditioned medium and methods of generating and using the same |
| US9567569B2 (en) | 2012-07-23 | 2017-02-14 | Gamida Cell Ltd. | Methods of culturing and expanding mesenchymal stem cells |
| US9175266B2 (en) | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
| JP5828823B2 (ja) * | 2012-09-28 | 2015-12-09 | クアーズテック株式会社 | 細胞培養モジュール及び細胞培養方法 |
| WO2014061675A1 (ja) * | 2012-10-17 | 2014-04-24 | コニカミノルタ株式会社 | 希少細胞の回収方法および検出方法 |
| JP2014124097A (ja) * | 2012-12-25 | 2014-07-07 | Hitachi High-Technologies Corp | 核酸分析用カートリッジ及び核酸分析装置 |
| EP3383998A4 (de) * | 2015-12-03 | 2019-07-31 | The Government of the United States of America, as represented by the Secretary of the Navy | Modularer bioreaktor zur kultivierung von gewebe auf biopapierbasis |
| CA3034452A1 (en) * | 2016-08-21 | 2018-03-01 | Adva Biotechnology Ltd. | Bioreactor and methods of use thereof |
| IL315340A (en) * | 2017-09-01 | 2024-10-01 | Lonza Walkersville Inc | End-to-end cell therapy automation |
| DE102018000561B4 (de) | 2018-01-24 | 2019-11-07 | Zellwerk Gmbh | Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben |
| DE202018000370U1 (de) | 2018-01-24 | 2018-04-12 | Zellwerk Gmbh | Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben |
| DE202018004857U1 (de) | 2018-10-20 | 2019-01-14 | Zellwerk Gmbh | Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen |
| US20230242864A1 (en) * | 2022-01-31 | 2023-08-03 | Sciperio, Inc | In-time storage of manufactured cells for medical cellular therapy grown and differentiated in bioreactors |
| EP4596667A1 (de) | 2024-01-30 | 2025-08-06 | Green Elephant Biotech GmbH | Bioreaktor und prozessleitsystem |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
| ZA839242B (en) * | 1982-12-15 | 1984-09-26 | Bio Response Inc | A method and system for culturing and treating substances disposed in a flowing culture fluid |
| US5135853A (en) * | 1983-07-22 | 1992-08-04 | Rensselaer Polytechnic Institute | Three compartment bioreactor and method of use |
| DE3409501A1 (de) * | 1984-03-15 | 1985-10-24 | Sandoz-Patent-GmbH, 7850 Lörrach | Verfahren zur kultivierung von zellen |
| US4894342A (en) * | 1986-05-12 | 1990-01-16 | C. D. Medical, Inc. | Bioreactor system |
| US4861483A (en) * | 1986-07-07 | 1989-08-29 | Cornell Research Foundation, Inc. | Apparatus and process to eliminate diffusional limitations in a membrane biological reactor by pressure cycling |
| US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
| KR100196062B1 (ko) * | 1989-06-15 | 1999-06-15 | 로버트 에프. 게이민 | 세포를 성장시키기 위한 방법, 조성물 및 장치 |
| EP0531631B1 (de) * | 1991-06-19 | 1996-10-09 | Endotronics, Inc. | Zellkultur Apparat |
| DE4206585C2 (de) * | 1992-03-03 | 1994-11-24 | Augustinus Dr Med Bader | Vorrichtung zur Massenkultur von Zellen |
-
1993
- 1993-03-04 AT AT93908270T patent/ATE225847T1/de not_active IP Right Cessation
- 1993-03-04 EP EP93908270A patent/EP0629236B1/de not_active Expired - Lifetime
- 1993-03-04 KR KR1019940703085A patent/KR100271284B1/ko not_active Expired - Fee Related
- 1993-03-04 DE DE69332374T patent/DE69332374T2/de not_active Expired - Lifetime
- 1993-03-04 CA CA002131385A patent/CA2131385C/en not_active Expired - Fee Related
- 1993-03-04 WO PCT/US1993/001803 patent/WO1993018132A1/en not_active Ceased
- 1993-03-04 AU AU39148/93A patent/AU685743B2/en not_active Ceased
- 1993-03-04 JP JP5515802A patent/JPH07504570A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0629236A1 (de) | 1994-12-21 |
| AU3914893A (en) | 1993-10-05 |
| AU685743B2 (en) | 1998-01-29 |
| KR100271284B1 (ko) | 2000-11-01 |
| EP0629236A4 (de) | 1997-06-04 |
| EP0629236B1 (de) | 2002-10-09 |
| JPH07504570A (ja) | 1995-05-25 |
| WO1993018132A1 (en) | 1993-09-16 |
| DE69332374D1 (de) | 2002-11-14 |
| CA2131385C (en) | 2008-07-15 |
| CA2131385A1 (en) | 1993-09-16 |
| DE69332374T2 (de) | 2003-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |