AR020999A1 - COMPOSITIONS AND PROCESS FOR THE ELABORATION OF ISOTRETINOIN - Google Patents

COMPOSITIONS AND PROCESS FOR THE ELABORATION OF ISOTRETINOIN

Info

Publication number
AR020999A1
AR020999A1 ARP990105436A ARP990105436A AR020999A1 AR 020999 A1 AR020999 A1 AR 020999A1 AR P990105436 A ARP990105436 A AR P990105436A AR P990105436 A ARP990105436 A AR P990105436A AR 020999 A1 AR020999 A1 AR 020999A1
Authority
AR
Argentina
Prior art keywords
isotretinoin
compositions
elaboration
micronized
micronization
Prior art date
Application number
ARP990105436A
Other languages
Spanish (es)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR020999A1 publication Critical patent/AR020999A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Proceso para la preparacion de una composicion de isotretinoína micronizada. El proceso se lleva a cabo por micronizacion de la isotretinoína mientras estásuspendida en un vehículo oleoso. Composiciones de isotretinoína micronizada y formas de dosificacion unitaria que contienen dichas composiciones.Process for the preparation of a composition of micronized isotretinoin. The process is carried out by micronization of isotretinoin while suspended in an oily vehicle. Micronized isotretinoin compositions and unit dosage forms containing said compositions.

ARP990105436A 1998-10-30 1999-10-28 COMPOSITIONS AND PROCESS FOR THE ELABORATION OF ISOTRETINOIN AR020999A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10633198P 1998-10-30 1998-10-30

Publications (1)

Publication Number Publication Date
AR020999A1 true AR020999A1 (en) 2002-06-05

Family

ID=22310843

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105436A AR020999A1 (en) 1998-10-30 1999-10-28 COMPOSITIONS AND PROCESS FOR THE ELABORATION OF ISOTRETINOIN

Country Status (13)

Country Link
EP (1) EP1131068A1 (en)
JP (1) JP2002528492A (en)
KR (1) KR20010073226A (en)
CN (1) CN1324235A (en)
AR (1) AR020999A1 (en)
AU (1) AU1044400A (en)
BR (1) BR9914932A (en)
CA (1) CA2347098A1 (en)
NO (1) NO20012014L (en)
PE (1) PE20001227A1 (en)
TR (1) TR200101156T2 (en)
WO (1) WO2000025772A1 (en)
ZA (1) ZA200102731B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7374779B2 (en) 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
DE19932157A1 (en) 1999-07-13 2001-01-18 Pharmasol Gmbh Process for the gentle production of ultra-fine microparticles and nanoparticles
FR2807662A1 (en) * 2000-04-12 2001-10-19 Cll Pharma PROCESS FOR STABILIZING THE SIZE OF AN ACTIVE INGREDIENT DISPERSE IN A LIQUID AND ITS APPLICATIONS
IN192188B (en) * 2000-06-16 2004-03-13 Ranbaxy Lab Ltd
CA2423170A1 (en) 2000-09-22 2002-03-28 Galephar M/F Pharmaceutical semi-solid composition of isotretinoin
EP1455730A4 (en) * 2001-12-06 2006-01-18 Ranbaxy Lab Ltd Isotretinoin nanoparticulate compositions
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
SE0303135D0 (en) * 2003-11-25 2003-11-25 Lipocore Holding Ab Controlled food effect composition
CZ300424B6 (en) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Pharmaceutical composition for peroral administration
US8309138B2 (en) 2007-02-16 2012-11-13 Aska Pharmaceutical Co., Ltd. Pharmaceutical composition comprising microparticle oily suspension
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
WO2010109259A1 (en) * 2009-03-26 2010-09-30 Grufarcol Ltda Method for preparing soft gel formulations of liquid isotretinoin and formulations obtained
US10022348B2 (en) 2009-05-20 2018-07-17 Sun Pharmaceutical Industries Limited Topical solution of isotretinoin
CN102802729A (en) 2009-05-20 2012-11-28 兰贝克赛实验室有限公司 Liquid dosage forms of isotretinoin
EP3006021A1 (en) 2009-05-20 2016-04-13 Ranbaxy Laboratories Limited Topical retinoid solutions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US9078925B2 (en) 2012-06-18 2015-07-14 Galephar Pharmaceutical Research, Inc. Pharmaceutical semi-solid composition of isotretinoin
JP6018845B2 (en) * 2012-09-03 2016-11-02 三生医薬株式会社 Method for producing capsule containing ultrafine powder
MX2016015465A (en) * 2014-05-29 2017-03-27 Sun Pharmaceutical Ind Ltd Oral pharmaceutical composition of isotretinoin.
RU2016150868A (en) * 2014-06-02 2018-07-17 Сан Фармасьютикал Индастриз Лимитед ORAL PHARMACEUTICAL COMPOSITION OF ISOTRETINOIN
MA40447A (en) * 2014-07-31 2016-02-04 Sun Pharmaceutical Ind Ltd Oral pharmaceutical composition of isotretinoin
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
MA40781A (en) * 2014-10-01 2017-08-08 Sun Pharmaceutical Ind Ltd PHARMACEUTICAL COMPOSITION OF LOW DOSAGE ISOTRETINOIN FOR ORAL USE
US9750711B2 (en) * 2014-10-01 2017-09-05 Sun Pharmaceutical Industries Limited Low dose oral pharmaceutical composition of isotretinoin
JP2018520114A (en) * 2015-05-25 2018-07-26 サン ファーマシューティカル インダストリーズ リミテッドＳｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｉｎｄｕｓｔｒｉｅｓ Ｌｔｄ． Oral pharmaceutical composition of isotretinoin once daily
US10517846B2 (en) 2016-05-26 2019-12-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for treating acne
US11559530B2 (en) 2016-11-28 2023-01-24 Lipocine Inc. Oral testosterone undecanoate therapy
AU2019308326B2 (en) 2018-07-20 2025-07-31 Lipocine Inc. Liver disease
AU2023301386A1 (en) 2022-07-01 2025-01-23 Acrotech Biopharma Inc. Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof
WO2024236523A1 (en) 2023-05-16 2024-11-21 Sun Pharmaceutical Industries Limited Once daily isotretinoin composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557615C2 (en) * 1975-12-20 1985-08-14 Bayer Ag, 5090 Leverkusen New niclosamide suspension formulations
DE3119383A1 (en) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING FINE DISTRIBUTED, POWDERED CAROTINO PREPARATIONS
CA1282326C (en) * 1984-12-14 1991-04-02 Paul J. Jarosz Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient

Also Published As

Publication number Publication date
NO20012014D0 (en) 2001-04-24
TR200101156T2 (en) 2001-08-21
NO20012014L (en) 2001-04-24
ZA200102731B (en) 2002-07-03
CA2347098A1 (en) 2000-05-11
PE20001227A1 (en) 2000-11-06
EP1131068A1 (en) 2001-09-12
CN1324235A (en) 2001-11-28
JP2002528492A (en) 2002-09-03
WO2000025772A1 (en) 2000-05-11
AU1044400A (en) 2000-05-22
KR20010073226A (en) 2001-07-31
BR9914932A (en) 2001-07-10

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