Jurnal Insan Farmasi Indonesia
Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia

FORMULASI SEDIAAN SIRUP EKSTRA ETANOL DAUN ILER (Coleus atropurpureus (L.) Benth) DAN UJI AKTIVITAS MUKOLITIK SECARA IN VITRO

Sulastri Herdaningsih (Unknown)
Dian Kartikasari (Unknown)



Article Info

Publish Date
27 May 2022

Abstract

Syrup is an oral liquid preparation containing sakarosa. The study aimed to test whether iler leaf extract (Coleus atropurpureus (L.) Benth) could be formulated as a syrup preparation then tested for physical properties and mucolytic activity. The experimental method used to test the mucolytic activity of iler leaf extract syrup in vitro is to measure the viscosity of duck egg whites added to the test solution every 15 minutes, namely at the 0th, 15th, 30th, 45th and 60th minutes. Testing of mucolytic activity was carried out on iler leaf extract syrup with concentrations of 3%, 4.5% and 6%, positive control of acetylcysteine 0.2% and negative control of aquades. The results showed that iler leaf extract syrup at concentrations of 3%, 4.5% and 6% can be formulated as syrup preparations and is able to significantly decrease the viscosity of duck egg whites compared to negative control.

Copyrights © 2022






Journal Info

Abbrev

JIFI

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics

Description

Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that ...