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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Salsabila, Tasya Viona
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Social Sciences Other

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Larvicidal Activity of Bay Leaf (Syzygium polyanthum) Ethanolic Extract in Addition of PEG Diluent on Aedes aegypti Larvae : Aktivitas Larvasida Ekstrak Ethanol Daun Salam (Syzygium polyanthum) Dengan Penambahan Pengencer PEG Terhadap Larva Nyamuk Aedes aegypti Dewi, Listiana Masyita; Salsabila, Tasya Viona; Bestari, Rochmadina Suci; Wahyuni, Sri
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16335

Abstract

Background: Dengue Fever (DF) is a viral infection disease transmitted by Aedes aegypti. It is one of Indonesian endemic diseases that reported to occur throughout the year. To break the transmission chain of DF, the use of larvicides is preferred, especially using natural ingredients, such as bay leaves (Syzygium polyanthum). Polyethylene glycol (PEG) as a dispersant may prevent the clumping of material test so that it can be distributed evenly in water which is the medium of growth for larvae. Objectives: To determine the effectiveness of ethanolic extract of bay leaves (EEBL) in addition of PEG diluent on the mortality of Aedes aegypti larvae. Material and Method: Bay leaves as the main material were extracted using 96% of ethanol, and were applied in two variation concentration, 0.75% and 1%, while the diluent added was PEG. The samples used in this study were Aedes aegypti larvae at stages III-IV, with a total of 25 individuals for each treatment group. Evaluation was performed every 6 hours, for 24 hours, then the results were recorded and analyzed using the Kruskall Wallis test and the Mann Whitney test. Result: In both of variation concentration used, at 24 hours of observation it was obtained the mortality of Aedes aegypti larvae was 100%. The p-value obtained for the Kruskall Wallis test was <0.05. From Mann Whitney test, when each of treatment group was compared to the positive control, abate®, the p-value obtained is >0.05, while when they were compared to the negative control, PEG, the p-value obtained is <0.05. Conclusion: 96% ethanolic extract of bay leaves in addition of PEG diluent is effective as Aedes aegypti larvicides. It is also known that EEBL at concentration of 0.75% and 1% in addition of PEG are as effective as abate® as Aedes aegypti larvicides.
The Incidence of Maxillofacial Trauma Post ORIF on The Incidence of Chronic Sinusitis Salsabila, Tasya Viona; Hafizh, Imam Nur; Adji, Iwan Setiawan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5543

Abstract

Purpose: This study aims to investigate the incidence of chronic sinusitis following Open Reduction and Internal Fixation (ORIF) for maxillofacial fractures. The research focuses on the impact of ORIF on sinus anatomy, drainage, and ventilation, leading to potential sinus complications. Methodology: The methodology used in this report is a clinical case study. Data were collected through anamnesis, physical examination, and supporting examinations. The patient's management was analyzed based on existing medical theories and appropriate treatment was provided according to the patient's condition. Results: Cases analyzed show common risk factors such as hematosinus, sinus flow obstruction, and postoperative swelling. The study emphasizes the need for post-surgical monitoring (3-6 months) to assess the development of sinusitis and related complications. Applications/Originality/Value: This report provides insights into the importance of early diagnosis and proper management maxillofacial trauma.The findings can be useful for healthcare professionals to understand clinical signs and effective treatment approaches for similar cases. Postoperative monitoring should include imaging and clinical evaluations to detect early signs of sinusitis.
Co-Authors Adji, Iwan Setiawan Hafizh, Imam Nur Listiana Masyita Dewi Rochmadina Suci Bestari Sri Wahyuni