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Patwa Amani, Patwa
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Pengaruh Low Level Laser Therapy (LLLT) terhadap Kadar Creatine Kinase (CK) dan Lactate Dehydrogenase (LDH) pada Proses Pemulihan Setelah Latihan Interval Intensitas Tinggi Amani, Patwa; Liana, Phey; Irfanuddin, Irfanuddin; Saleh, Irsan
Biomedical Journal of Indonesia: Jurnal Biomedik Fakultas Kedokteran Universitas Sriwijaya Vol 1, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Penelitian mengenai Low Level Laser Therapy (LLLT) pada subjek manusia maupun hewan coba telah diketahui memberikan hasil positif terhadap penanganan penyakit inflamasi, perbaikan jaringan, dan penanganan nyeri. Meskipun demikian penggunaan LLLT pada bidang kedokteran olahraga masih sangat terbatas. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh LLLT terhadap kadar creatine kinase (CK) dan lactate dehydrogenase (LDH) sebagai biomarker kerusakan otot setelah latihan interval intensitas tinggi. Penelitian eksperimental kuasi dengan rancangan single-blind, randomized, placebo controlled dilakukan dengan 20 orang subjek laki-laki sehat yang tidak terlatih. Subjek dibagi menjadi dua kelompok yakni kelompok dengan LLLT aktif dan kelompok kontrol plasebo. Setiap kelompok akan melakukan latihan interval intensitas tinggi mneggunakan sepeda statis dengan intensitas kayuh 50%-80% HR maksimal selama 30 menit. Segera setelah latihan fisik kelompok perlakuan akan diberikan LLLT (810nm, 5mW, 40 Joule) menggunakan probe multi diode pada 4 titik untuk masing-masing tungkai bawah, sedangkan kelompok kontrol menerima plasebo. Kadar CK dan LDH diukur dua kali, yakni sebelum latihan interval intensitas tinggi dan 24 jam setelahnya. Terdapat perbedaan kadar CK yang signifikan antara kelompok LLLT (105,50 ± 47,12) dan kelompok kontrol (182,91 ± 49,77) (p<0,05). Hasil pengukuran kadar LDH juga menunjukan hasil yang signifikan dengan rerata kelompok LLLT 144,37 ± 15,96 dan kelompok kontrol 183,88 ± 30,19 (p<0,05).
LOW VITAMIN B12 DIET INCREASES LIVER HOMOCYSTEINE LEVELS AND LEADS TO LIVER STEATOSIS IN RATS Sianipar, Imelda Rosalyn; Ujianti, Irena; Yolanda, Sophie; Jusuf, Ahmad Aulia; Kartinah, Neng Tine; Amani, Patwa; Murti, Krishna Aditya; Soeria Santoso, Dewi Irawati
Universa Medicina Vol 38, No 3 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (821.825 KB) | DOI: 10.18051/UnivMed.2019.v38.194-201

Abstract

Background Nonalcoholic fatty liver disease (NAFLD) is one of the most widespread chronic liver diseases, caused by the development of insulin resistance. One of the mechanisms involved is a disturbance in insulin signaling by certain toxic substances that interact with one of the proteins responsible for the insulin signaling pathway. Increased homocysteine level, upon disruption of the methionine pathway, is associated with insulin resistance. The aim of this study was to evaluate the effect of hyperhomocysteinemia and insulin resistance (HOMA-IR level) induced by dietary vitamin B12 restriction on liver steatosis. Methods A study of laboratory experimental design was conducted involving 18 male Sprague Dawley rats (age 36-40 weeks, BW 300-350 g), that were randomly divided into 3 groups: control, 8-week treatment, and 16-week treatment. Standard AIN-93 diet was administered to the control group, whereas rats in the treatment groups were fed vitamin B12 deficiency-AIN-93M. At the end of treatment, liver homocysteine levels were determined by ELISA, HOMA-IR values were calculated, and steatosis degree of the liver was determined histologically. Statistical analysis was performed using independent t-test. Results A significant increase in liver homocysteine levels was found between the control and both the 8- and 16-week treatment groups (p&lt;0.001). HOMA-IR levels were significantly higher in both treatment groups compared to controls (p&lt;0.001). The area of liver steatosis in both treatment groups was significantly larger than that of the control group (p&lt;0.001). Conclusion Increased homocysteine levels due to dietary vitamin B12 deficiency induces liver steatosis due to insulin resistance in rats.
Effect of Brain Gym ® exercises on cognitive function and brain-derived neurotrophic factor plasma level in elderly: a randomized controlled trial Adriani, Donna; Imran, Yudhisman; Mawi, Martiem; Amani, Patwa; Ilyas, Ermita I.I.
Universa Medicina Vol 39, No 1 (2020)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.732 KB) | DOI: 10.18051/UnivMed.2020.v39.34-41

Abstract

BackgroundCognitive impairment and dementia are some of the major health concerns in the aging population. Many studies showed positive effects of physical exercise in delaying or preventing these conditions. Brain Gym ® exercises is a structured aerobic exercise involving head, eyes and crossing movements of the extremities in order to stimulate both brain hemispheres. This study was conducted to evaluate the effect of Brain Gym ® exercises sessions on cognitive function and plasma brain-derived neurotrophic factor (BDNF) in the elderly.MethodsA non-blinded randomized controlled study involving 64 healthy women aged &gt;60 years who were randomized into Brain Gym ® exercises treatment group (n=32) and control group (n=32). Treatment group joined 60 minutes of brain gym exercises sessions twice a week for 12 weeks. The measured outcomes were cognitive function (assessed by mini-mental state examination [MMSE] questionnaire) and plasma BDNF levels. The outcomes were measured at base-line and after the intervention. An independent t-test was used to analyze the data.ResultsThe BDNF levels were increased in both groups after 12 weeks, and there was a significant difference between treatment group (41.26 ± 6,82 ng/mL) and control group (37.10 ± 8.11 ng/mL)(p=0.040). However, the MMSE score was not significantly different between the two groups (p=0.200).ConclusionBrain Gym ® exercises sessions significantly increase plasma BDNF level in the elderly population. In practical terms, we may suggest evaluation of the effects of Brain Gym ® exercises as a strategy in the treatment of disorders associated with central degenerative changes.
Obesity is the most influential risk factor of cardiopulmonary endurance in older women Khairani, Rita; Adriani, Donna; Amani, Patwa
Universa Medicina Vol. 40 No. 3 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.254-262

Abstract

BackgroundPulmonary function decreases with age. Similarly, physical exercise capacity measured by maximal oxygen uptake, which is one indicator to measure the level of cardiac and pulmonary vascular resistance, decreases by >1% per year. This results in many respiratory diseases that occur in older persons, especially in obese older persons. Pulmonary function is a basic component of cardiopulmonary endurance, besides other factors such as age, hemodynamics, metabolism, and lifestyle. The objective of this study was to determine whether body mass index (BMI) and pulmonary function have a significant association with cardiopulmonary endurance in older women. MethodsThe study used a cross-sectional design involving 66 subjects aged 60 years and older in South Jakarta. Data was collected by measuring body mass index (BMI), pulmonary function (FEV1, FVC, FEV1/FVC) and maximal oxygen uptake (VO2 max) for cardiopulmonary endurance. Data analysis used simple and multiple linear regression tests in SPSS v.25, with p<0.05. ResultsOf the 66 older persons, 57.6% was obese. Pulmonary function of subjects showed restriction (33.3%), obstruction (6.1%) and a combination of restriction and obstruction (1.5%). Furthermore, mean VO2 max was 12.2 mL/kg/min. Multiple linear regression analysis showed a significant association of BMI and FEV1/FVC with VO2 max (â =-0.56; 95% CI=-0.81 - (-) 0.31; p=0.000; â =0.09; 95% CI=0.01-0.18; p=0.028). BMI was the most influential risk factor of VO2 max (Beta = -0.46). ConclusionsThere was a significant association of BMI and FEV1/FVC with VO2 max, BMI being the most influential risk factor of cardiopulmonary endurance in older women.
Defisiensi Vitamin B12: Tinjauan Aspek Fisiologi dan Dampak Spesifik terhadap Ginjal Vitamin B12 Deficiency: Insight of Physiological Aspect and the Specific Impact to the Kidney Amani, Patwa
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 7, Nomor 1, Januari 2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v7i1.10769

Abstract

Defisiensi vitamin B12 (VB12) saat ini masih merupakan masalah kesehatan masyarakat di seluruh dunia baik negara maju maupun berkembang. Selain karena kurangnya intake, terdapat berbagai penyebab terjadinya defisiensi VB12 yang berkaitan dengan fisiologi absorbsi dan utilisasi seluler vitamin B12. Dampak dari defisiensi VB12 bukan saja terjadi pada sistem hematologi yang secara klasik sudah diketahui, namun memiliki dampak pada berbagai sistem tubuh salah satunya organ ginjal. Beberapa laporan kasus menunjukan adanya hubungan antara kelainan gen yang terlibat dalam proses absorbsi vitamin B12 dengan penyakit ginjal progresif kronis. Review ini bertujuan membahas defisiensi VB12 yang ditinjau dari aspek fisiologi serta dampak khususnya pada organ ginjal.
KAJIAN FAKTOR SOSIODEMOGRAFI DAN POLA AKTIVITAS FISIK PADA MAHASISWA DENGAN CHRONIC FATIGUE SYNDROME DI SEKOLAH TINGGI SEMI-MILITER Amani, Patwa; Puspita, Sekar Melati Putri
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 7, Nomor 2, Juli 2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v7i2.14044

Abstract

Sekolah tinggi semi-militer merupakan salah satu jenis pendidikan tinggi di Indonesia yang memiliki pola pendidikan dengan karakteristik khusus. Selama masa studi mahasiswa tinggal di asrama dengan jadwal akademik yang sangat padat dan kurangnya fleksibilitas dalam pola istirahat serta kegiatan harian. Kondisi tersebut dapat memicu stres jangka panjang yang dapat mengarah pada kejadian chronic fatigue syndrome (CFS). Studi mengenai faktor risiko CFS pada mahasiswa perlu dilakukan untuk mengurangi angka kejadian dan komplikasinya. Penelitian analitik observasional dengan desain cross- sectional dilakukan pada 150 mahasiswa sekolah tinggi semi-militer yang terdiri atas 123 laki-laki dan 27 perempuan. Penilaian aktivitas fisik menggunakan Global Physical Activity Questionnare dan Centers for Disease Control Symptom Inventory Questionnare untuk penilaian chronic fatigue syndrome. Dari hasil penelitian diketahui rerata responden memiliki tingkat aktivitas fisik berat dengan rerata skor GPAQ 6875,18. Prevalensi CFS pada responden adalah 30%, dengan persentase tertinggi pada kelompok usia ≥ 20 tahun, jenis kelamin laki-laki, dan tingkat akademik tahun pertama.
MENGHAFAL AL-QURAN: TINJAUAN FUNGSI KOGNITIF Adriani, Donna; Amani, Patwa; Putri, Mustika Anggiane; Imran, Yudhisman; Fauzi, Ahmad
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 9, Nomor 1, Januari 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v9i1.17487

Abstract

Cognitive function is a mental process consisting of knowledge, information processing, and reasoning. Cognitive functions include the domains of perception, memory, learning, attention, decision-making, and language skills. Assessment of cognitive functions consists of attention and concentration, executive function, memory, language, visuoconstruction skills, conceptual thinking, calculation, and orientation. Cognitive disorder is a maladaptive response characterized by impaired memory, disorientation, incoherence and difficulty thinking logically. Memorization involves various complex processes called basic cognitive processes which include encoding, storing, and recalling memories, because these processes occur in many memory systems that function differently but are interconnected with one another. Al-Quran is the holy book of Muslims that comes from Allah SWT and was revealed through the Prophet Muhammad SAW. Memorizing the Al-Quran can stimulate the neurotrophin factor. In adulthood, there is a decrease in cognitive function of 6.7%. Cognitive function can be assessed from the serum levels of Brain Derived Neurotrophic Factor (BDNF) and serum Nerve Growth Factor (NGF). Brain Derived Neurotrophic Factor is a protein that increases the survival of neurons and synapses that play a role in learning and memory processes. Nerve Growth Factor is a protein that plays a role in the growth, development and maintenance of nerve cells. The purpose of this study is to explain physiologically the effect of memorizing the Al-Quran on cognitive function in terms of serum BDNF and NGF levels. Based on the results of several studies, it was found that memorizing the Al-Quran continuously can improve cognitive function.
PENYULUHAN DAN PELATIHAN BRAIN GYM PADA MAHASISWA DI LEBAK BULUS DAN PARUNG Adriani, Donna; Amani, Patwa; Putri, Mustika Anggiane; Imran, Yudhisman; Rachmiyani, Irmiya
JUARA: Jurnal Wahana Abdimas Sejahtera Volume 5, Nomor 2, Juli 2024
Publisher : Jurusan Teknik Lingkungan Fakultas Arsitektur Lanskap dan Teknologi Lingkungan, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/rh01pz91

Abstract

Tujuan kegiatan penyuluhan dan pelatihan Brain Gym ini adalah meningkatkan pengetahuan, sikap, dan perilaku tentang manfaat Brain Gym dalam meningkatkan fungsi kognitif, serta meningkatkan kesehatan masyarakat. Kemampuan ini meliputi orientasi, proses mengingat, menilai, persepsi serta memperhatikan. Brain gym adalah suatu bentuk olahraga dengan gerakan yang memiliki keseimbangan, menyilang, yang dapat mengaktifkan kedua hemisfer otak dan menstimulasi neuron sensoris dan motorik. Brain Gym dapat meningkatkan fungsi kognitif salah satunya dinilai melalui kadar BDNF serum, jika dilakukan secara teratur, berulang- ulang, dan terstruktur. Brain gym dapat meningkatkan konsentrasi pada penderita Diabetes Melitus grup Prolanis Putewa Jakarta Timur. Metode PkM adalah penyuluhan tentang manfaat Brain Gym terhadap fungsi kognitif, pelatihan Brain Gym, diskusi tanya jawab, serta pengisian kuesioner. Program Pengabdian kepada Masyarakat ini dilaksanakan dengan sasaran mahasiswa Perguruan Tinggi di Lebak Bulus, Jakarta dan Parung, Bogor, Jawa Barat. Berdasarkan kuesioner didapatkan hasil pengetahuan peserta: sangat baik 8,11 %, baik 56,76 %, kurang 35,13 %; sikap: sangat baik 33,78 %, baik 40,54 %, kurang 25,68 %; perilaku: sangat baik 31,08 %, baik 64,87 %, kurang 4,05 %. Kesimpulan: Sebagian besar peserta memiliki pengetahuan, sikap, dan perilaku yang baik.  
Penyuluhan Perawatan Kulit Pada Wanita Lanjut Usia Saroso, Ade Firman; Sutanto, Hans Utama; Adriani, Donna; Amani, Patwa; Putri, Mustika Anggiane; Imran, Yudhisman; Rachmiyani, Irmiya; Nasution, Dina Putri; Jordhi, Dimas
JUARA: Jurnal Wahana Abdimas Sejahtera Volume 5, Nomor 1, Januari 2024
Publisher : Jurusan Teknik Lingkungan Fakultas Arsitektur Lanskap dan Teknologi Lingkungan, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/juara.v5i1.18257

Abstract

The general aim of this activity is expected to improve the level of public health, especially in Nagrak Village. The specific aim of this activity is to increase elderly women's knowledge about skincare, the participants can carry out skin care independently and appropriately so as to improve skin health and quality of life. The methods used were education about skin care, pretest as initial data to determine knowledge about skincare, and posttest to determine knowledge after being given education. The results of this activity were the mean pretest knowledge about skincare was 1.97 ± 1.07 and the mean posttest knowledge about skincare was 3.1 ± 0.99. Conclusion: elderly women's knowledge increased after being given education. The significance and implications of this activity are that the target is to understand the process of skin aging that occurs due to increasing age as well as good and appropriate care according to the condition of elderly women's skin. Skincare that can be done for elderly women is using sunscreen of at least SPF 30 in outdoor activity, drinking at least 2000 mL of water per day, using facial moisturizer, and cleaning the face with a cleanser containing mineral oil. We consider this theme important because skin health is a reflection of beauty in general and a reflection of health
Antioxidants as future medicines: redox homeostasis concept Amani, Patwa
Universa Medicina Vol. 43 No. 2 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.133-135

Abstract

Co-Authors Adriani, Donna Ahmad Aulia Ermita I.I. Ilyas Fauzi Ahmad Muda Fayola, Aurelia Putri Handayani, Astri Imelda Rosalyn Sianipar Irena Ujianti Irfanuddin Irfanuddin Jordhi, Dimas Layal, Kamalia Lewa, Shintya Clara Paiding Martiem Mawi Muhammad Irsan Saleh Murti, Krishna Aditya Nasution, Dina Putri Neng Tine Kartinah Almuktabar Nugraha, Alfjari Febri Oktika Dagis, Nyai Phey Liana Puspita, Sekar Melati Putri Putri, Mustika Anggiane Rachmiyani, Irmiya Rita Khairani, Rita Santoso, Dewi Irawati Soeria Saroso, Ade Firman Sophie Yolanda Sutanto, Hans Utama Syarinta Adenina Yudhisman Imran, Yudhisman