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All Journal Jurnal Farmasi Udayana
Jannatu Yasmin Adiningsih
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Medicine & Pharmacology

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TINGKAT PENGETAHUAN, PERSEPSI DAN SIKAP APOTEKER DI APOTEK MENGENAI COVID-19 DI KOTA YOGYAKARTA susan Fitria Candradewi; Wiwin Nopita Putri; Jannatu Yasmin Adiningsih
Jurnal Farmasi Udayana Vol. 11, No. 2, Tahun 2022
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2022.v11.i02.p02

Abstract

The Corona virus found in Wuhan gives challenges for health workers such as pharmacists who are responsible for providing education to the public, especially regarding COVID 19. The aim of the study was to measure the level of knowledge, perceptions and attitudes of community pharmacists in Yogyakarta regarding COVID-19. The research design was analytic observational with a population of pharmacists who practiced in community pharmacies in Yogyakarta and the sample was a community pharmacists who practiced for at least 6 months. The results showed that community pharmacists in Yogyakarta had good knowledge about COVID-19 (60%) and 40% of them had sufficient knowledge. Pharmacists who have a positive perception was 66% and who have a negative perception was 34%. The attitude of pharmacists shows 68% positive and 32% negative. The relationship between education level and pharmacist's knowledge, perception and attitude obtained p-values ??of 0.241, 0.806 and 0.094, respectively, while the relationship between length of work experience and pharmacist's knowledge, perceptions and attitudes obtained p-values ??of 0.010, 0.352, and 0.022, respectively. The conclusion of this study is that pharmacists at the Yogyakarta City pharmacy have good knowledge, positive perceptions and attitudes about COVID-19 and there is a relationship between length of work experience and knowledge and attitudes (p<0.05).
SIFAT FISIKOKIMIA DAN LAJU DIFUSI PATCH TRANSDERMAL DISPERSI PADAT MELOKSIKAM YANG MENGGUNAKAN NATRIUM LAURIL SULFAT SEBAGAI PENINGKAT PENETRASI Anisa Amalia; Nining Nining; Jannatu Yasmin Adiningsih
Jurnal Farmasi Udayana Vol. 11, No. 2, Tahun 2022
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2022.v11.i02.p01

Abstract

Meloxicam is a non-steroidal anti-inflammatory medicine (NSAID) with gastrointestinal side effects, hence it's used in transdermal patch preparations as a substitute. Meloxicam was dispersed in PEG 6000 (1:8) and formed as a transdermal patch using sodium lauryl sulfate as a penetration enhancer in this study. The purpose of this study is to see how sodium lauryl sulfate, used as a penetration enhancer, affects the physicochemical characteristics and diffusion of meloxicam in solid dispersion transdermal patches. The patch comes in four different formulas, each with a different concentration of sodium lauryl sulfate: 0% (F0), 1% (F1), 3% (F2), and 5% (F3). The physicochemical parameters of each formula were evaluated, including organoleptic tests, pH, thickness, weight uniformity, moisture content, and folding resistance, as well as diffusion tests. Each formula's transdermal patch has physicochemical characteristics that fulfill the literature's standards. The percentage of meloxicam diffused in each formula was 80.6683 percent, 85.8091 percent, 90.7508 percent, and 93.3322 percent, respectively, with each formula's diffusion rate kinetics following Higuchi's kinetics. The physicochemical characteristics and diffusion rate of the meloxicam transdermal patch were altered by sodium lauryl sulfate (p < 0.05). The most promising patch as an alternative to meloxicam dosage form is meloxicam solid dispersion transdermal patch formulation with 5% sodium lauryl sulfate content.
Co-Authors Anisa Amalia Nining Nining Susan Fitria Candradewi Wiwin Nopita Putri