An experiment was carried out to investigate the efficacy of herbicide combinations between Tetris and Basagran for weed eradication, especially for Leptochloa chinensis and Echinochloa crus-galli, in rice plant using direct planting system. This experiment was done between May and September 2011 in Biromaru, District of Sigi, Central Sulawesi. There were 12 treatments tested and arranged in a randomized block design, namely: Tetris 0.75 l/ha + Basagran 2 l/ha, Tetris 0.75 l/ha + Basagran 3 l/ha, Tetris 1 l/ha + Basagran 2 l/ha, Tetris 1 l/ha + Basagran 3 l/ha, Tetris 1.2 l/ha + Basagran 2 l/ha, Tetris 1.2 l/ha + Basagran 3 l/ha, Tetris 1 l/ha + Invest 400g + 2.4D 0.8 l/ha, RiceStar-Xtra 0.5 l/ha + 2.4D 0.8 l/ha, Cliper 0.5 l/ha + 2.4D 0.8 l/ha, Rumpas 0.3 l/ha + 2.4D 0.8 l/ha, Pyzaro 1 l/ha + 2.4D 0.8 l/ha, and control (without herbicide). Each of these treatments was replicated three times and applied at 10 and 20 days after planting. The results indicated that all the herbicide combinations were able to eradicate total and dominant weeds in the tested rice field. The dominant weeds that were eradicated including grass weed (Ischaemum rugosum, Leptochloa chinensis and Echinochloa crus-galli), “teki” (Cyperus iria and Fymbristilis miliacea) as well as a broadleaf weed (Ludwigia octovalvis). It was also found that the application of Tetris and Basagran combination in a rice plantation using the direct planting system at 10 days after planting was more effective than at 20 days after planting, and the recommended ranges of combination is between 0.75+2 l/ha and 1+2 l/ha.