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All Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico
Ni Nyoman Ayu Dewi
Department of Biochemistry, Faculty of Medicine, Udayana University, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Administration of ethanol extract of Bajakah tampala (Spatholobus littoralis Hassk) stem decreased reactive oxygen species, visceral fat and body weight of obese rats Vany Novanty; Wimpie Pangkahila; Ni Nyoman Ayu Dewi
Neurologico Spinale Medico Chirurgico Vol 4 No 1 (2021)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v4i1.150

Abstract

Background: Oxidative stress plays a role in the obesity mechanism, thus leads to premature aging. High antioxidant capacity in Bajakah tampala stem may effectively lessen oxidative stress and reduce fat mass and body weight accordingly. This study aimed to provide Bajakah tampala stem extract's effect in lowering ROS level, visceral fat weight, and overall weight of obese male Wistar rats. Method: A true experimental design was conducted on male Wistar rats aged 2-3 months with obesity. Thirty-two obese rats were evenly divided into a placebo group and a group given Bajakah tampala stem extract, with 16 rats in each group. For 28 days, both groups were fed a high-fat diet. The subject body weights were weighed every week. ROS levels and visceral fat weight were evaluated after the intervention was done. Comparative analysis between groups was performed. Results: The results showed mean levels of ROS (56.2 ± 7.4 U/ml vs. 400.9 ± 50.7 U/ml; p < 0.001), visceral fat weight (2.6 ± 0.2 g vs. 3.4 ± 0.9 g; p < 0.001), and the final body weight (241.5 ± 2.8 g vs. 261.5 ± 13.8 g; p < 0.001) were significantly lower in the study group than the control group. Conclusion: The study indicates Bajakah tampala stem extract administration effectively reduced ROS levels, visceral fat weight, and body weight in obese male Wistar rats.
Level of awareness among female medical students towards risk factors of breast cancer at Faculty of Medicine, Udayana University, Bali, Indonesia Daarshini Bhaskavan; Ni Nyoman Ayu Dewi; I Wayan Surudarma
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.065 KB) | DOI: 10.15562/ism.v9i3.282

Abstract

Background: Breast cancer is the most commonly diagnosed cancer among women in the vast majority of countries worldwide that is triggered by several risk factors This study aims to determine the level of awareness among female medical students towards risk factors of breast cancer at Faculty of Medicine, Udayana University, Bali, Indonesia.Method: A cross-sectional descriptive study was conducted on 56 female medical students of Udayana University. A self-administered questionnaire consisting of 25 questions were used where 0 indicates for wrong answers or “don‟t know‟ and a one is given for the correct answer. A total score of >20 is considered having an excellent level of awareness, 16-20 for good level of awareness, 10-15 for moderate level of awareness, and < 10 means poor level of awareness.Result: Most of participants had moderate level of awareness (71.4%), followed by a poor level of awareness (17.9%), good level of awareness (10.7%), and there were no participants had high level of awareness (0%).Conclusion: Most female medical students had a moderate level of awareness towards risk factors of breast cancer.
The level of knowledge regarding breast cancer among female high school students at Santo Yoseph School, Denpasar, Bali, Indonesia Hemalatha Thiruchelvam; Ni Nyoman Ayu Dewi; Ida Ayu Dewi Wiryanthini
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.195 KB) | DOI: 10.15562/ism.v10i3.459

Abstract

Background: Breast cancer is the second leading cause of death among women around the world. In Indonesia, breast cancer is the leading cause of death among women. Previous studies have shown that female students have limited knowledge of breast cancer. This study is aimed at assessing the level of breast cancer knowledge among female high school students in Santo Yoseph School, Denpasar.Methods: A cross-sectional survey of 96 female high school students in Santo Yoseph School, Denpasar, was conducted using a self-administered questionnaire.  Questions asked in the questionnaire were about general knowledge of breast cancer, risk factors towards breast cancer, signs and symptoms of breast cancer and knowledge of Breast Self-Examination. The data was tabulated by scoring only the correct answers and analysed using SPSS version 17 for Windows.Results: The result of the study showed that high school female students had moderate to good knowledge of breast cancer. Fifty-three (55.2%) female students had average knowledge and forty-three (44.8%) female students had good knowledge of breast cancer. The majority of the participants, seventy-five (78.1%) of them, knew that breast cancer was the leading cause of death among women in Indonesia.Conclusion: The recent findings showed that female high school students had good knowledge of breast cancer. Good knowledge of breast cancer is important for girls and women equally.
Co-Authors Daarshini Bhaskavan Hemalatha Thiruchelvam I Wayan Surudarma Ida Ayu Dewi Wiryanthini Vany Novanty Wimpie I Pangkahila