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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Ensiklopedia of Journal Jurnal Perawat Indonesia G-Tech : Jurnal Teknologi Terapan Abdi Masya Jurnal Studi Keperawatan DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN JOINTECOMS (Journal of Information Technology and Computer Science)
Teguh Wahyudi
Nursing Department, Polytechnic Health Ministry of Semarang
Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Energy Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Cocoa extract has activity on selectively killing of breast cancer cells line tunjung-sari, ariza budi; Mahriani, Mahriani; Tiningrum, Gusti Agung Perias; Wahyudi, Teguh; Jati, Misnawi
Journal of Tropical Life Science Vol 5, No 3 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.03.04

Abstract

Effect of the cocoa crude extract on mortality of breast cancer cell lines i.e. MCF-7, T47D and normal cell (Vero), was observed. Crude cocoa extract prepared from a freshly dried cocoa bean that was containing 14% catechin and 0.6% caffeine. Catechin and caffeine content were modulated to 2-folds (28% catechin or 1.2% caffeine) and 3-folds (42% catechin or 1.8% caffeine) by adding pure compounds. Extracts were dissolved in dimethylsulfoxide (DMSO) at concentrations ranging from 200 to 1600 μg/ml. The positive control was doxorubicin (0.5-16 μg/ml in DMSO). Cell lines (MCF-7, T47D, and Vero) were incubated in test sample for 24h at 37°, prior to 3-(4,4-dimetylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The absorbance of each well was measured at 550 nm, and lethal concentration (LC50) was calculated. The cocoa extract induced mortality of breast cancer cell lines but not in Vero cells. The effect on MCF-7 was greater than on T47D, given the LC50 was 1236 μg/ml (MCF-7) and 1893 μg/ml (T47D). Cytotoxic potential of cocoa extract was much lower than doxorubicin whose LC50 was0,777 μg/ml (MCF-7) and 0,082 μg/ml (T47D). Increasing catechin content to 2-folds did not significantly affect LC50 value, but 3-folds catechin content reduced LC50 to 1021 μg/ml. Meanwhile increasing caffeine content to 2-folds significantly reduced LC50 to 750 μg/ml, however, 3-fold content resulted in slightly higher LC50 at 780 μg/ml. This indicates that cocoa extract have anti-cancer potential, and purification may improve this property .
Relationship between Cysteine, Interleukin (IL)-2, And Interleukin (IL)-10 in Children with Marasmus Type Malnutrition Wahyudi, Teguh; Puryatni, Anik; Hernowati, Tinny Endang
Journal of Tropical Life Science Vol 6, No 1 (2016)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.06.01.10

Abstract

 Malnutrition is one of the health issues in developing countries. The most commonly found malnutrition is the marasmus type. Infection in marasmus patient is the main cause of morbidity and mortality in developing countries. In marasmus, there is a decrease in protein level such as cysteine which is one of the glutathione forming components that plays a significant role in immune system. In malnutrition, there is a disturbance of lymphocyte in the form of down-regulation of type 1 cytokine (IL-2 and IFN-γ) and up- regulation of type 2 cytokine (IL-4 and IL-10). IL-2 is needed for the development of regulatory T produced by thymus and for NK cell cytotoxicity which plays a role in infection process, while IL-10 inhibits activation of lymphocyte T so the cellular immunity reaction ends. Several studies about the relationship between cysteine, IL-2, and IL-10 have been done in malnutrition-patients, but there is no study focusing on patients with marasmus. This study is to find out the relationship between cysteine, IL-2, and IL-10 in patients with marasmus type malnutrition. This study was an observational analytic study using cross-sectional design consisting of 20 children with marasmus type malnutrition and 20 well-nourished children treated in Saiful Anwar Hospital Malang. The cysteine, IL-2, and IL-10 level then measured using Elisa method. Normality and the various test were done. The Pearson correlation test was done to find out the relationship between cysteine and IL-2 level, cysteine and IL-10 level, and IL-2 and IL-10. The standard of cysteine and IL-2 level in children with marasmus is significantly lower than the control group, which was 1.616 ± 1.039 vs 3.298 ± 0.519 pg/mL; p = 0.000 dan 12.38±4.94 vs. 16.58 ± 4.80 pg/mL;p = 0.010, respectively. IL-10 in children with marasmus was significantly higher than control group (19.08± 5.93 vs 10.46 ± 3.90 pg/mL; p = 0.000). The cysteine level was positively correlated to the IL-2 level (p = 0.000; r = 0.71), while the cysteine and IL-10, IL-2 and IL-10 was negatively correlated with p = 0.014; r= -0.53 and p=0.037; r= -0.46 in marasmus. There was a positive correlation between the cysteine and IL-2 level and negative correlation between IL-10 and IL-2 also IL-2 and IL-10 in children with marasmus. 
PENGARUH RANGE OF MOTION ROM ) AKTIF TERHADAP FLEKSIBILITAS SENDI LUTUT PADA LANJUT USIA Indrayana, Tavip; Wahyudi, Teguh
Jurnal Perawat Indonesia Vol. 4 No. 2 (2020): August 2020
Publisher : Persatuan Perawat Nasional Indonesia (PPNI) Jawa Tengah.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.402 KB) | DOI: 10.32584/jpi.v4i2.224

Abstract

Perubahan fleksibilitas sendi pada lanjut usia dapat ditangani dengan menggunakan latihan Range of Motion (ROM) aktif. Beberapa penelitian menunjukkan bahwa latihan ROM aktif secara signifikan meningkatkan fleksibilitas sendi lutut sebesar 35° pada 43,75% responden dari total sampel. Penelitiam ini bertujuan untuk menganalisa pengaruh latihan ROM aktif pada ekstremitas bawah terhadap peningkatan fleksibilitas sendi lutut pada lansia. Metode penelitian ini menggunakan pendekatan quasy-eksperiment dengan pendekatan one group pre-test and post-test design.Teknik sampling menggunakan total sampling yaitu sebanyak 25 lansia. Pengkuran dilakukan pada saat hari ke-1, hari ke-4 dan hari ke-8 penelitian dengan menggunakan alat ukur goniometer. Hasil analisa data pada hari ke-1 menunjukkan bahwa rata-rata fleksibilitas sendi lutut pada responden adalah sebesar 117,52o. Selanjutnya analisa pada hari ke-4 menunjukkan adanya peningkatan rata rata fleksibilitas sendi lutut yaitu menjadi 122,24o (meningkat menjadi 4,72o). Pengukuran terakhir juga meperlihatkan adanya peningkatan rata rata fleksibilitas sendi lutut yaitu menjadi 125,88 o (meningkat sebesar 8,36o apabila dibandingkan dengan fleksibilitas sendi lutut hari ke-1yang meningkat sebesar 3,64 o apabila dibandingkan dengan hari ke-2) sehingga dapat disimpulkan bahwa latihan ROM aktif dapat meningkatkan fleksibilitas sendi lutut pada lansia. AbstractChanges of joint flexibility in the elderly can be treated by using active ROM (Range of Motion) exercises. Several studies have shown that active ROM exercises significantly increase the flexibility of the knee joint by 35° among 43.75% of the total sample. The aim of this study was to analyze the effect of active ROM exercises on the lower extremities on increasing the flexibility of the knee joint in the elderly. The Study employed a quasi-experimental approach with One group pre-test and post-test design and ulitilized total sampling method. The Measurrement is carried out on the 1st day, 4th day and 8th day of the study using a goniometer instrument. Data analysis on the 1st day showed that the average ROM among respondents was 117.52o. Furthermore, the analysis on the 4th day showed an increase in the average knee joint ROM, which was 122.24o (increased to 4.72o). The last measurement also showed an increase in the mean angle of the knee joint ROM which was 125.88o (increased by 8.36o when compared to the 1st day ROM and increased by 3.64o when compared to the 2nd day). It can be concluded that active ROM exercise can increase the range of joint motion in the elderly.
Managing Stroke Rehabilitation in Elderly Cipto, Cipto; Wahyudi, Teguh; Normawati, Ajeng Titah
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 11 No 1 (2023): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jdk.v11i1.198

Abstract

The world's elderly population is predicted to triple every year, and have complex consequences such as the incidence of non-communicable diseases, one of which is stroke. Stroke is a disease of impaired brain function that is a global health problem. As many as 2.5% of the 500 thousand stroke sufferers experience disability and even mortality in Asian countries, especially Indonesia. The study describes a rehabilitation program for the stroke elderly with a family approach. Three elderly stroke survivors were given passive and active range of motion exercises in the extremities by their families accompanied by nurses for 10 consecutive days. The results were obtained that all three elderly experienced an increase in muscle strength in part of their extremities at one rate better. From this study, it can be seen that rehabilitation with a family approach can be used as an alternative to improve the mobility ability of the elderly after stroke at home
KORELASI ASPEK PENGETAHUAN DAN SIKAP KELUARGA TERHADAP TINDAKAN PENCEGAHAN DEMAM BERDARAH DENGUE Nurjanah, Nourma; Inayati, Inna Noor; Salamung, Niswa; Wahyudi, Teguh; Zen, Suharno
Ensiklopedia of Journal Vol 6, No 4 (2024): Vol. 6 No. 4 Edisi 3 Juli 2024
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v6i4.2538

Abstract

Abstract: DHF is a public health problem that tends to be increasingly widespread, in line with the increasing flow of transportation and population density. This disease is found in almost all parts of the world, especially in tropical and subtropical countries both endemically with outbreaks associated with the arrival of the rainy season. The purpose of this study was to determine the Relationship between Family Knowledge and Attitudes towards Preventive Measures for Dengue Hemorrhagic Fever in the Pusako Health Center Working Area. This type of research is quantitative research with research design used cross sectioanal research design with a total sample of 93 people. Data analysis used chi square test analysis. The results showed that there was a significant relationship between knowledge (p value 0.002) and attitudes (p value 0.000) towards dengue disease prevention measures in the Bantan Health Center Working Area in 2022. It is recommended that respondents can expand their knowledge even more about the prevention of dengue disease for future life through guidance by health workers, especially about the prevention of dengue disease.Keywords: DHF, Knowledge, Attitude
Studi Faktor-Faktor Yang Mempengaruhi Ibu Hamil Trimester II Dalam Pencegahan Stunting Prasetyo, Agus; Wahyudi, Teguh; Abidin, M. Zainal; Astuti, Yuni
Jurnal Studi Keperawatan Vol 5, No 1 (2024): MARCH 2024
Publisher : Program Studi Keperawatan Blora, Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/j-sikep.v5i1.11235

Abstract

Upaya pencegahan stunting paling baik adalah 1000 HPK (hari pertama kehidupan),  dimulai sejak awal kehamilan untuk mencegah terjadinya stunting pada anak dikemudian hari. Stunting dapat terjadi selama masa kehamilan karena kurangnya asupan gizi, pola makan yang tidak adekuat, dan kualitas makanan yang rendah, yang semuanya dapat menghambat pertumbuhan janin. Oleh karena itu, penting untuk memberikan perhatian yang cukup terhadap kesejahteraan ibu hamil agar dapat mencegah terjadinya stunting pada anak yang dikandungnya.Tujuan penelitian untuk mengetahui gambaran faktor-faktor perilaku ibu hamil trimester II dalam mencegah stunting pada balita. Desain penelitian ini adalah deskriptif analitik korelasional. Populasi penelitian adalah ibu hamil trimester II yang berkunjung di klinik swasta di Kecamatan Kota Blora, dengan sampel 49 orang secara purposive sampling. Hasil Penelitian memperlihatkan bahwa hamil pada trimester II sebesar 73,7 % memiliki perilaku yang baik dalam pencegahan stunting. Hasil uji bivariat menunjukan umur 35 tahun (p=0,025), pendidikan perguruan tinggi (p=0,001), ibu bekerja (p=0,001), dan multigravida (p=0,034) berhubungan dengan perilaku baik dalam pencegahan stunting. Simpulan dari penelitian ini adalah perilaku ibu hamil yang baik dalam pencegahan stunting berada pada usia 35 tahun, pada tingkat pendidikan perguruan tinggi, pada ibu yang bekerja dan multigravida. Saran: Direkomendasikan kepada petugas di pelayanan baik negeri maupun swasta untuk meningkatkan penyuluhan perilaku pencegahan stunting pada ibu hamil, terutama melalui posyandu atau kunjungan Ante Natal Care (ANC).
DETERMINAN KEJADIAN TB PARU PADA USIA PRODUKTIF Amaliah, Lili; Rosdiana, Rosdiana; Wahyudi, Teguh; Wirda, Wirda
Ensiklopedia of Journal Vol 7, No 3 (2025): Vol. 7 No. 3 Edisi 3 April 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i3.3089

Abstract

Abstract: Tuberculosis (TB) is a direct infectious disease caused by Mycobacterium Tuberculosis. Based on document searches, in 2023, Putri Ayu Health Center was one of the health centers with the highest incidence of TB and experienced an increase in cases compared to the previous year, reaching 95 cases. The purpose of the study was to determine the determinants of the incidence of pulmonary TB in productive age. The research design used in this study was Case Control. The research was conducted in the working area of the Putri Ayu Health Center. The research was conducted from May to July 2024. The study population was all cases of Tb in the Putri Ayu Health Center work area totaling 97 people. The research sample has a ratio of 1: 1 so that the sample amounted to 114 people. The sampling technique used in this study was Simple Random Sampling. Data analysis was done univariate and bivariate. The results showed a relationship between income (p value: 0.031) and contact history (p value: 0.024) to the incidence of TB. It is recommended that the community, especially those with low income and a history of TB contact, should receive more attention from health workers to ensure TB screening in communities with risk factors and with TB symptoms.Keywords: Income, Contact History, Tuberculosis.
Perancangan Sistem Informasi Penjualan Air Galon Isi Ulang Di Kota Palangka Raya Berbasis Web Wahyudi, Teguh; Sahay, Abertun Sagit; Sylviana, Felicia
JOINTECOMS (Journal of Information Technology and Computer Science) Vol. 2 No. 2 (2022): JOINTECOMS : Journal of Information Technology and Computer Science
Publisher : Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1005.175 KB) | DOI: 10.47111/jointecoms.v2i2.8851

Abstract

This system was built with the aim of being a medium of sales information for refilling gallon water depots and providing information for people who want to buy refill gallon water. With this system, it is expected to be useful as a medium for expanding information about refill gallon water depots, helping consumers to purchase gallons of refill water easily, and the purchase of refill gallon water can be done without the need for the charging depot location. The methodology used in the manufacture of "Refill Gallons of Water Sales Information Systems Design in the City of Palangka Raya Based on Web" is Waterfall According to Ian Sommerville, the Requirement Analysis and Definition, System and Software Design, Implementation and Unit Testing, Integration and System Testing, and Operation and maintenance. This methodology was chosen because every step of structured development was visualized, and clearly documented. At the analysis stage, data collection and needs analysis were made. At the design stage, Data Flow Diagram (DFD) and Entity Relationship Diagram (ERD) are made. At the implementation stage, the system is made using PHP and Javascript as a programming language, and MySQL as a database server. The test method used is the Blackbox Testing method. Test results using this Blackbox method from the analysis process until the implementation is obtained that the system can carry out data processing such as adding/saving, deleting, changing, and searching. Users can enter data and data can be processed and produce location, product, transaction, and report information. "Refill Gallon Water Sales Information Systems Design in the City of Palangka Raya Based on Web" is able to provide information needed by customers and visitors. In the system there are several features that can be used by the admin, operators, customers and visitors though. So that the functionality of this website is appropriate in accordance with the initial purpose of making the system, "Refill Gallon Water Sales Information Systems Design in the City of Palangka Raya Based on Web " can still be developed again.
Thematic Community Service Lecture (KKNT): Revitalization of the Potential of “Kali Mati” as a Tourist Attraction in Parangjoro Village Saputro, Eko Wahyu; Wahyudi, Teguh; Alfarizi, Fikri Yudi; Tilfah, Raffi Abdullah Al-Latif; Hendriyanto, Deva; Fathurohman, Arif; Ramadhan, Gilang; Jamaldi, Agus; Hidayah, Fatimah Nur
Abdi Masya Vol 6 No 1
Publisher : Pusat Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52561/abdimasya.v6i1.422

Abstract

Thematic Community Service Lecture (KKNT) is a student activity that implements knowledge gained in lectures that is applied to life in society. Students, as agents of change, are expected to be able to provide alternative solutions to problems that exist in society. Parangjoro Village is one of the villages in Grogol District, Sukoharjo Regency, Central Java. This village has good tourism potential to be developed, namely the "Kali Mati" river flow. Currently, "Kali Mati" has not been optimally managed by the village government; the area around the location is used for illegal garbage dumping by irresponsible individuals. Seeing the problems like this, a solution is needed so that the existing potential can be managed and developed better. The KKNT activity carried out by students seeks to organize the "Kali Mati" location to manage its potential as a tourist attraction in Parangjoro Village. The activity begins with the location survey stage, coordinating with residents in the Singkil area, RT 03/08, Parangjoro Village, determining the concept of location arrangement, implementing activities and evaluating the results of activities. Based on the results of the survey at the location and interviews with residents, it is necessary to carry out waste dumping/piling activities so that the location on the edge of "Kali Mati" looks clean. Furthermore, lighting is needed so that the location is brighter at night. Next, fish seeds are spread as a way of preserving the waters of "Kali Mati" and also as an effort to attract residents and tourists to Keli Mati in the future. The results of the activities carried out at this time are that the location, which was initially dirty and unorganized, has become cleaner and more comfortable for the community. At night, the area is also brighter, and many people spend their nights hanging out around the location. Based on these results, the KKNT activities carried out by students can positively contribute to the community in Parangjoro village, especially residents of Singkil RT 03/08, and provide real experience for students in life in society.
Implementation of PLC Outseal in the Control and Monitoring System for Chicken Farming Using SCADA Haiwell Wahyudi, Teguh; Abidin, Zainal; Bachri, Affan
G-Tech: Jurnal Teknologi Terapan Vol 9 No 4 (2025): G-Tech, Vol. 9 No. 4 October 2025
Publisher : Universitas Islam Raden Rahmat, Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/g-tech.v9i4.7800

Abstract

The rapid growth of the poultry industry necessitates efficient environmental control in chicken farming. One of the main challenges is the high concentration of ammonia gas (NH₃) from chicken manure, which can adversely affect chicken health and productivity. This study presents the design and implementation of an automated control and monitoring system for chicken farms using a Programmable Logic Controller (PLC) Outseal and a Supervisory Control and Data Acquisition (SCADA) Haiwell. The system aims to maintain optimal environmental conditions, particularly ammonia gas concentration and temperature, which are critical for poultry health and productivity. The system utilizes MQ-135 and LM35 sensors to monitor ammonia and temperature levels, respectively, and is built on a master-slave architecture using the MODBUS RTU protocol. Data is transmitted in real-time to the SCADA dashboard, enabling automated control of the blower system. Experimental results demonstrated that the system effectively maintained ammonia levels between 20–35 ppm and temperature between 35–38°C. The LM35 sensor achieved an average error rate of 0.83%, while the MQ-135 sensor showed an error of 1.80%. The RS-485 communication protocol enabled stable data transfer up to 200 centimeters. These results indicate that the system can significantly improve poultry farming management through automation and environmental optimization.
Co-Authors Agus Prasetyo Ajeng Titah Normawati Alfarizi, Fikri Yudi Amaliah, Lili Anik Puryatni Arif Fathurohman, Arif ariza budi tunjung-sari, ariza budi Bachri, Affan Cipto Cipto, Cipto Felicia Sylviana Gilang Ramadhan Gusti Agung Perias Tiningrum, Gusti Agung Perias Hendriyanto, Deva Hidayah, Fatimah Nur Inayati, Inna Noor Jamaldi, Agus M. Zainal Abidin Mahriani Mahriani Misnawi Jati Nourma Nurjanah Rosdiana Rosdiana Sahay, Abertun Sagit Saputro, Eko Wahyu Suharno Zen Tavip Indrayana, Tavip Tilfah, Raffi Abdullah Al-Latif Tinny Endang Hernowati Wirda Wirda Yuni Astuti Zainal Abidin