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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Lukman Hakim
Fakultas Farmasi, Universitas Gadjah Mada Yogyakarta
Health Professions Medicine & Pharmacology Public Health

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THE STRATEGY FORMULATION OF PHARMACY DEPARTMENT TO IMPROVE STAKEHOLDER SATISFACTION Deviana Eka Oktaviantari; Lukman Hakim; Endang Yuniarti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.108

Abstract

Pharmacy department at Yukum Medical Centre Hospital (IFRS YMC) Central Lampung can not avoid the effects of tight business competition, so it needs to improve the services quality continuously. The purpose of this research was to analyse stakeholder satisfaction of pharmacy department services, and to formulate strategies to increase the stakeholder satisfaction. This research was a descriptive study with qualitative and quantitative data. Qualitative data were obtained by in-depth interviews, whereas quantitative data were acquired using questionnaires to measure satisfaction of stakeholder and pharmacy department staffs. The internal and external environments were analyzed, followed by SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis. The result was used as data to formulate strategies followed by Quantitative Strategic Planning Matrix (QSPM) test to sequence priorities of the chosen strategies as strategy development of IF RSYMC Central Lampung. The result stated that IFRS YMC Central Lampung had bigger opportunities (average score=1.36) than threats (1.27), and had smaller strengths (1.69) than weaknesses (1.73). The priority of alternative strategies based on QSPM test was developing technologies to support services, following national or international accreditation for hospitals, improving the capacity and quality of human resources in IFRS, and formulating a written standard operating prosedure to whole service in IFRS YMC Central Lampung.Keywords : SWOT analysis, QSPM test, Pharmacy Department,
ESTIMATED LEVELS OF PHENYTOIN IN BLOOD AND RESULTS THERAPY OF EPILEPSY PATIENTS Satrio Wibowo Rahmatullah; Lukman Hakim; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.111

Abstract

Medicines with a narrow therapeutic range such as phenytoin require individual dose, monitoring, and strict assessment of the patient to maintain the safety of the patient. It is because small changes in systemic concentration can lead significant changes in the pharmacodynamic responses, such as subtherapeutic or toxic. This study aimed to determine the relationship between dose and phenytoin levels in the blood included clinical outcome of patients with epilepsy based on the duration of seizure-free at the Sleman Regional General Hospital, Yogyakarta. This study was a descriptive observational study. The sampling method was purposive sampling. The data was collected retrospectively on epilepsy patients with phenytoin treatment both inpatient and outpatient from January 2010 to December 2012, male or female who were routinely controlled for at least 6 consecutive months. Patients were grouped into monotherapy and combination therapy groups. Clinical outcome was observed through the duration of the seizure-free and devided into 2 categories i.e. < 6 months (poor outcome) and ≥ 6 months (a good outcome). The results showed that male (53.6%) have a greater percentage than female (46.4%). Estimated blood levels of phenytoin was in the average 5.30±4.03 mg/L. Based on the duration of seizure free, the results showed that the percentage of patients in monotherapy group had good and poor outcomes with 71.83% and 28.17% respectively, while only 50% patients in combination therapy group had good outcome.Keywords: phenytoin, epilepsy, nonlinear, clinical outcome
EVALUATION OF VALPROIC ACID DOSE USED FOR PAEDIATRIC WITH EPILEPSY Herningtyas Nautika Lingga; Lukman Hakim; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.112

Abstract

Epilepsy is a chronic disease in neurology and the second most common disorder after stroke. Valproic acid is categorised to the medicine with a narrow therapeutic index which requires monitoring of plasma drug levels and dose adjustments to prevent toxic effects. This study aimed to determine the estimated value of valproic acid concentration in serum and clinical outcomes in paediatric patients with epilepsy observed from seizure-free duration at Sleman Regional General Hopital, Yogyakarta. This study was a retrospective study with descriptive observational design. Subjects were paediatric patients with epilepsy who received valproic acid treatment over the period of January 2010-December 2012, 1 to 18 years old, boys or girls who were routinely controlled for at least 6 consecutive months. Clinical outcomes were observed through the duration of the seizure-free which were devided into 2 categories i.e. <6 months (unfavorable outcome), and ≥ 6 months (a good outcome). The proportion of 99 patients who met the inclusion criteria were 27.28% less than or equal to 5 years old, whereas 5-12 years and 12-18 years age groups had the same percentage which was 36.36%. From the calculation, average estimated value of valproic acid concentrations in serum for girls group were as much as 86.32±49.25 mg/L and 33.26±22.06 mg/L, while in boys group were as much as 94.91±44.72 mg/L and 38.57±20.72 mg/L. Based on the duration of seizure free, clinical outcome showed that the percentage of patients in monotherapy group had good and poor outcomes with 52.33% and 46.67% respectively, while 61.54% and 38.46% of patients in polytherapy group had good and poor outcome respectively.Keywords: Epilepsy, Valproic Acid, Clinical Outcome, Paediatric
Co-Authors Deviana Eka Oktaviantari Endang Yuniarti Herningtyas Nautika Lingga I Dewa Putu Pramantara Rahmatullah, Satrio Wibowo