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PENGGUNAAN METODE RASIO ABSORBAN DALAM PENETAPAN KADAR PARASETAMOL DAN SALISILAMIDA BERBENTUK SEDIAAN CAMPURAN Armin, Fithriani; Dantes, Ehrlich Von
Jurnal Sains dan Teknologi Farmasi Vol 17, No 2 (2012)
Publisher : Universitas Andalas

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A study on the determination of paracetamol and salicylamide in a mixture by absorbance ratio method has been done. The absorption spectrum of both compounds crossing one each other at isoabsorption point. The maximum wavelength of paracetamol, salicylamide, and wavelength of isoabsorpsi line which show the relation of paracetamol fractions in a mixture containing paracetamol and salicylamide in various proportions and absorbances at isoabsorption wavelength was constructed. The measurement of absorbance was done at 247,2 nm and 300,3 nm. The experiment showed that the absorbancy ratio method can be used to determine paracetamol and salicilamyde. The percent recovery of paracetamol was 101,31 % with 0,642 % of standard deviation and coefficient of variation 0,616 %. The salicylamide content was then calculated and found to be 99,66 % with 0,863 % of standard deviation and 0,861 % of coefficient variation.

Penggunaan Metode Rasio Absorban dalam Penetapan Kadar Parasetamol dan Salisilamida Berbentuk Sediaan Campuran Dantes, Ehrlich Von; Armin, Fithriani; Rusdi, Rusdi
Jurnal Sains dan Teknologi Farmasi Vol 17 No 2 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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A study on the determination of paracetamol and salicylamide in a mixture by absorbance ratio method has been done. The absorption spectrum of both compounds crossing one each other at isoabsorption point. The maximum wavelength of paracetamol, salicylamide, and wavelength of isoabsorpsi line which show the relation of paracetamol fractions in a mixture containing paracetamol and salicylamide in various proportions and absorbances at isoabsorption wavelength was constructed. The measurement of absorbance was done at 247,2 nm and 300,3 nm. The experiment showed that the absorbancy ratio method can be used to determine paracetamol and salicilamyde. The percent recovery of paracetamol was 101,31 % with 0,642 % of standard deviation and coefficient of variation 0,616 %. The salicylamide content was then calculated and found to be 99,66 % with 0,863 % of standard deviation and 0,861 % of coefficient variation.

Identifikasi dan Penetapan Kadar Merkuri (Hg) dalam Krim Pemutih Kosmetika Herbal Menggunakan Spektrofotometri Serapan Atom (SSA) Armin, Fithriani; Zulharmita, Zulharmita; Firda, Dinda Rama
Jurnal Sains dan Teknologi Farmasi Vol 18 No 1 (2013)
Publisher : Fakultas Farmasi Universitas Andalas

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Telah dilakukan penelitian analisis kandungan merkuri dalam 3 sampel krim pemutih kosmetika herbal. Sampel diekstraksi dengan cara digesti basah selama 3 jam pada suhu Â±95Â°C sampai diperoleh larutan bening. Selanjutnya merkuri ditentukan secara kualitatif dan kuantitatif dengan pereaksi warna dan menggunakan metoda spektrofotometri serapan atom. Hasil analisis kualitatif menunjukkan bahwa semua sampel mengandung merkuri. Kadar merkuri pada sampel 1, 2, 3 berturut-turut adalah sebesar 0,56%; 0,28% dan 0,45 %. Kadar Hg pada sampel tersebut melanggar Peraturan Menkes RI No.376/MenKes/Per/VIII/1990 dan PerMenKes RI No.445/MenKes/Per/V/1998 yang isinya melarang penggunaan merkuri dalam sediaan kosmetika.

Edukasi Deteksi Dini sebagai Upaya Preventif Kanker Payudara dan Edukasi Langkah Pengobatan Kanker Payudara Fithriani Armin; Fatiya Juwita Hanum; Ida Rahmah Burhan; Hayatun Nufus; Nurul Hidayati
Warta Pengabdian Andalas Vol 26 No 4.a (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

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October is celebrated as the month of caring breast cancer worldwide, pioneered by Susan G. Komen for the Cure, a foundation for breast cancer in the United States. The month of October was used as a momentum to increase awareness of the importance of recognizing breast cancer which is the key to reducing new cases and the stages of advanced breast cancer. The government is optimizing efforts to prevent and control breast cancer. The role of breast cancer survivors' organization, Lovepink Indonesia research partner, which consists of breast cancer survivors and warriors is needed in sharing knowledge and experience in breast cancer treatment. Based on this, the collaboration between partners and universities can be elaborated by conducting education, socializing the importance of early detection of breast cancer as well as educating treatment steps through medical treatment to the public delivered by patients who have survived with breast cancer. Counseling, sharing experiences and practices of SADARI and SADANIS explanations are the methods used. The results of the implementation of this activity were reviewed directly from the high enthusiasm of the participants as evidenced by the desire to follow the SADARI technique movement and the emergence of questions to survivors about the experience and safety of treatments such as chemotherapy. The importance of the results of community service will trigger public knowledge about breast cancer has an impact on reducing the stage of advanced breast cancer patients thereby improving the quality of life of people and sufferers.

Penentuan Kadar Senyawa Fenolat Dan Uji Aktivitas Antioksidan Pada Buah Terung Belanda (Cyphomandra betacea (Cav.) Sendtn) Secara Spektrofotometri Visibel Fithriani Armin; Yuli Yani Dewi; Mahyuddin Mahyuddin
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Levels Determination of phenolic compounds and antioxidant activity assay of eggplant belanda fruit (Cyphomandra betacea (Cav.) Sendtn) with visible spektofotometri has been done. Determination of phenolic compounds performed by the method of Folin ciocalteu, while DPPH is used as an antioxidant. The antioxidant activity is determined by its IC50 value. In this treatment gallic acid used as a comparison. The results showed that the levels of phenolic compounds from the sample extract solution is 0.288845 mg / g; 0.29678 mg / g and 0.28964 mg / g respectively. The antioxidant activity determined by IC50 values, where the value of its IC50 was 240.0811 µg / mL; 204.5010 µg / mL; 196.8531 µg / mL.

Pembuatan Kalsium Glukonat Dari Batu Kapur Bukit Tui Padang Panjang Zulharmita Zulharmita; Sri Indah Kesuma; Fithriani Armin
Jurnal Farmasi Higea Vol 6, No 1 (2014)
Publisher : STIFARM Padang

A study concerning the manufacture of calcium gluconate limestone hill Tui Leopold. Previous limestone samples were identified and determined the levels of calcium. 1 g sample of limestone calcium levels obtained 36,0812 %. In the manufacture of calcium gluconate used limestone samples of 20 g were dissolved in 6 M HCl, filtered and the filtrate was added 6 M NH4OH to pH 10 . Then added gluconic acid 1 M. The precipitate is filtered, washed, dried in an oven at a temperature of 1050 C. The results obtained as 6,2084 g of calcium gluconate. Examination of limestone calcium gluconate include organoleptic examination, solubility, qualitative identification, examination and the melting point of the assay by the method complexometry. In the assay of calcium gluconate from the manufacture of natural limestone samples carefully weighed approximately 0,5 g , 1 g, and 2 g. Of the three differences in weight percentage of calcium gluconate calcium results obtained, weighing 0,5 g to as much as 62,2708 % , 1 g weight as much as 79,9048 %, while the weight of as much as 2 g 101,7232 %. From the results of the assay of calcium gluconate with a sample of 6,2084 g drying results have percentage 101,7232 % with the results of testing the melting point is 2000 C calcium gluconate. It can be concluded natural limestone hill Tui Leopold has a high purity calcium levels that can be made of calcium gluconate.

Analisis Senyawa Fenolat Dan Uji Aktivitas Antioksidan Buah Markisa (Passiflora Edulis Sims) Secara Spektrofotometri Visibel Fithriani Armin; Ermadanis Ermadanis; Roslinda Rasyid
Jurnal Farmasi Higea Vol 6, No 2 (2014)
Publisher : STIFARM Padang

Has done research on the analysis of phenolic compounds and antioxidant activity test on passion fruit (Passiflora edulis Sims) by visible spectrophotometry method. To determine the presence of phenolic compounds in the sample to be identified with iron (III) chloride is characterized by the formation of dark blue color on the sample. Samples were macerated with 96% ethanol, performed three repetitions and the filtrate was concentrated using a rotary evaporator at a temperature of 400 C. Extracts were obtained determined the levels of phenolic compounds using Folin-ciocalteau method and test the antioxidant activity using DPPH method. Standard solution used is gallic acid. Equation linearity gallic acid used in the determination of phenolic compounds in the sample is y = 0.004x + 0.1366 with correlation coefficient (r) = 0.9956 measured at λ max 761.5 nm. the levels of phenolic compounds were obtained on average at the sample was 0.0377% w / w. The average percent inhibition of passion fruit sample solution were counted against the maximum wavelength of 512.0 nm DPPH is 19.8763%. The antioxidant activity of the sample solution of 10 mg is equivalent to 618.9760 mg gallic acid and gallic acid solution IC50 of 1.5604 mg / mL of the sample solution while the IC50 14.4751 mg / mL.

Pembangan dan Validasi Metode Kromatografi Lapis TipisDensitometri untuk Analisis Pewarna Merah Sintentik pada Beberapa Merek Saus Sambal Sachet Fithriani Armin; Bita Revira; Adek Zamrud Adnan
Jurnal Sains Farmasi & Klinis Vol 2, No 1 (2015): J Sains Farm Klin 2(1), November 2015
Publisher : Fakultas Farmasi Universitas Andalas

Chili sauce sachet A, B and C containing synthetic red coloring agent were taken from three fast food premises in Padang. Synthetic red coloring agent were a food additives used by food manufacturers to enhance color of food products. The use of food coloring agent in Indonesia were regulated in The Rule of Head of the Supervisory Food Board of the Republic of Indonesia Number 37 Year 2013 about the Limit Use of Food Coloring Agent. Thin-layer chromatography (TLC) -densitometry was a precision method for the analysis of food additives. Development and validation of TLC method for chromatographic separation used GF254 silica plate eluted with a mixture of ethanol: butanol: distilled water (4: 5: 5) and spots were detected visually. A red spots on the sample B was identified as Ponceau 4R with Rf value of 0.76. It was then followed by quantitative analysis using densitometry. The linearity of the method was found in the range of 2-10μg/ml with a correlation coefficient of 0.994. Precision intra-day and inter-day relative standard deviation was shown from 1.11% and 2.69% respectively. Accuracy of the method was shown on the percentage of recovery of the 3 different concentrations of solution which gave the average percentage of 108.17%. Limit of detection and limit quantitation was 0.8306μg/ml and 2.7687μg/ml. The concentration of Ponceau 4R in the sample B was 11.9520mg/kg of material. This value was not exceeded the maximum concentration of food coloring agent as stated in the rule which should not be above 70mg/kg of material.

Formulation and evaluation of antibacterial activity of hand sanitizers containing red betel (Piper crocatum) and white galangal (Alpinia galanga) extract Faridah BD, Faridah BD; Saputri, Lita Angelina; Fitriah, Iin Prima; Rahmawati, Lisa; Oktavia, Nike Sari; Armin, Fithriani
MEDISAINS Vol 22, No 1 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i1.21357

Background: The COVID-19 outbreak has changed how people live worldwide, making hand hygiene a must, whether it involves hand sanitizer (HS). The majority of HS are made of alcohol. Several side effects of alcohol are dryness and allergies. Alternative natural ingredients and HS are needed. Red betel (Piper crocatum) and white galangal (Alpinia galanga) are familiar and easy to be found. These two plants have the potential to be the composition of HS because of their compounds, such as antioxidants, antibiotics, antifungals, and antivirals. However, there is a need for further research on their formulation and effectiveness in germ-killing.Purpose: To formulate and identify the antibacterial activity of HS containing red betel and white galangal extract.Method: This research was an in vitro laboratory experiment with several steps, including extraction, specific and nonspecific tests, formulation, and antibacterial activity tests.Results: Red betel and white galangal leaves had been extracted at a concentration of 10% and formulated into HS. The HS containing 10% red betel extract produced an inhibition zone of 0 mm against E. coli and 1.05 mm against S. aureus, and the HS containing 10% White galangal extract produced an inhibition zone of 1.47 mm against E. coli and 1.40 mm against S. aureus.Conclusion: The formulation of HS containing 10% of white galangal extract is more effective than the HS containing 10% of Red betel extract.

Analisis Kadar Vitamin B1 dalam Kacang Panjang (Vigna sinensis L.) Menggunakan Spektrofotometri Ultraviolet-Visible Fithriani Armin; Regina Andayani; Denny Hilson; Azzaky Azzaky
Jurnal Geografi, Lingkungan dan Kesehatan Vol 1 No 1 (2023): Jurnal Geografi, Lingkungan dan Kesehatan
Publisher : Program Studi Pendidikan Geografi Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/jglk.1.1.9977

A Research of vitamin B1 in long beans (Vigna sinensis L.) analyzed using ultraviolet-visible (uv-vis) spectrophotometry has been carried out at a wavelength of 435.6 nm. Vitamin B1 reacted with bromthymol blue to form a yellow ion-associated complex in an ammonia-ammonium chloride as a buffer solution pH 7.6 which could be observed with a polyvinyl alcohol solubilizing agent. Long beans were boiled in water for 5, 10 and 15 minutes at 100oC. Vitamin B1 in long beans (Vigna sinensis L.) without boiling 0.0981 % ± 0.00021, boiling 5, 10 and 15 minutes were 0.0935 % ± 0.00015; 0.0834 % ± 0.00010 and 0.0743 % ± 0.00010 and the vitamin B1 in the long bean boiled water at 5, 10 and 15 minutes boiling were 0.00102 % ± 0.000004; 0.00110 % and 0.00117 % ± 0.00001. It’s can be concluded that boiling long beans (Vigna sinensis L.) can cause a decrease in vitamin B1 which decreases with increasing boiling time and vitamin B1 in the cooking water increase due to the nature of vitamin B1 which is easily soluble in water

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