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All Journal Kesmas: Jurnal Kesehatan Masyarakat Nasional The Indonesian Journal of Occupational Safety and Health Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL JK Unila (Jurnal Kedokteran Universitas Lampung) Essential: Essence of Scientific Medical Journal Industrika : Jurnal Ilmiah Teknik Industri Respiratory Science Journal of Scientech Research and Development The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy

Agus Dwi Susanto

Departement Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Indonesia

Author-ID : 3604901

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Epidemiological and Clinical Features of COVID-19 Patients at National Emergency Hospital Wisma Atlet Kemayoran, Jakarta,Indonesia Agus Dwi Susanto; Anna Rozaliyani; Budi Prasetyo; Heidy Agustin; Hario Baskoro; Arief Riadi Arifin; Satria Pratama; Jamal Zaini; Bambang Dwi Hasto; Tugas Ratmono; Ary Indriana Savitri; Erlang Samoedro; Bahtiar Husain; Arifin Nawas; Erlina Burhan
Jurnal Kesehatan Masyarakat Nasional Volume 16, Special Issue No 1, 2021
Publisher : Faculty of Public Health Universitas Indonesia

The emergency hospital is intended to prevent transmission of COVID-19 in the community by isolating patients without symptoms, with mild or moderate symptoms. This study evaluated the clinical characteristics and outcomes of COVID-19 patients who were admitted to this facility. This retrospective study reviewed data of patients treated at the National Emergency Hospital Wisma Atlet Kemayoran in Jakarta, Indonesia, from March 23 to April 30, 2020. Patient characteristics (clinical symptoms, laboratory test results, Chest X-Ray, SARS-CoV-2 immunoserology, and RT-PCR results from nasopharyngeal/ oropharyngeal preparations) were compared between severity groups. There were 413 COVID-19 cases analyzed, of which 190 (46%) were asymptomatic, 93 (22.5%) were mild, and 130 (31.5%) were moderate cases. Most asymptomatic cases were male, with young age, and without comorbidity. Mild cases were dominated by female and young patients, while most moderate cases were male and older patients. The number of patients with comorbidities was higher in mild and moderate cases. The patient’s overall outcome was good and did not differ based on the severity of symptoms. Despite the many challenges, patients with moderate symptoms can be safely treated in the emergency hospital.

Lung Function Impairment Among Firefighter After Forest Fire Disaster in Riau, Sumatra Rudi Kurniawan; Seira Putri Boru Rambe; Indra Yovie; Erlang Samoedro; Agus Dwi Susanto; Jamal Zaini
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.210

Background: The 2015 forest fire disaster affected almost 2.6 million hectares of land in Indonesia, and Riau was among the worst. Firefighters were the first responders to deal with the disaster, but a little was known about the influence of extinguishing forest fire activities with their health. This study aimed to evaluate respiratory symptoms and lung function among firefighters 6 months after forest fire exposure.Methods: Interviews were conducted regarding sociodemographic factors, respiratory symptoms, and history of forest fire exposure during the disaster. Spirometry and chest X-ray were also carried out with standard techniques. Statistical analysis was performed based on the existing data. Ninety firefighters participated in this study, most were male with mean age of 33 years old. About 66% were smoker, had been working as firefighters for 2 to 10 years, and had been on extinguishing forest fire duty around 2–5 hours/day during the disaster.Results: All firefighters reported respiratory symptoms after 3 months. Pulmonary function was abnormal in 50% of subjects with mild restrictive characteristic. The analysis showed that body mass index (BMI) and duration of exposure had a significant correlation with pulmonary function abnormality.Conclusion: Pulmonary function was found abnormal in most subjects 6 months after forest fire exposure in Riau.

Urinary Cotinine and Expired CO Concentrations in Women Exposed to Environmental Tobacco Smoke at Home Herman Suryatama; Feni Fitriani; Sita Andarini; Agus Dwi Susanto; Achmad Hudoyo
Jurnal Respirologi Indonesia Vol 39, No 3 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Introduction: The health effects of exposure to environmental tobacco smoke (ETS) using cotinine was a nicotine metabolite detected in urine. This should be recommended as a quantitative measurement of nicotine intake and as biomarker for ETS exposure in humans. Method: We performed a cross-sectional study to 60 ETS-exposed and 58 non ETS exposed adult women in Pasar Rebo area, Jakarta. The urinary cotinine concentrations were measured and analyzed using ELISA method, other informations were collected such as expired CO data, questionnaire regarding smoking habits of the subjects’ family members at home and respiratory health effects occured to subjects. Results: Median of urinary cotinine concentrations in ETS-exposed group were 24.65 ng/ml and 7.30 ng/ml in non-exposed group (P=0.0001). Median of expired CO in ETS-exposed group were 5.00 ppm and 3.00 ppm in non-exposed to ETS group (P=0.0001). Total amount of time (hours/day) in women exposed to ETS in their house was significantly correlated to urinary cotinine concentrations (P=0.037). The respiratory symptoms showed significant correlation with ETS exposure status (P=0.01). Time duration of last exposed to ETS had significant correlation with expired CO (P=0.004). The urinary cotinine concentrations cut-off point was 14.4 ng/ml (sensitivity=75%, specificity=74%, P=0.0001). The expired CO cut-off point was 3.5 ppm (sensitivity=75%, specificity=81%, p=0.0001). Strong and significant correlation was found between expired CO and urinary cotinine (r=0.641, P=0.0001). Conclusion: The urinary cotinine and expired CO concentration were significantly higher in women exposed to tobacco smoke at home than the non-exposed group. Urinary cotinine measurement was a sensitive, non-invasive and effective method to correlate with ETS exposure. (J Respir Indo. 2019; 39(3):140-53)

Inflammatory Markers upon Admission as Predictors of Outcome in COVID-19 Patients Budhi Antariksa; Erlina Burhan; Agus Dwi Susanto; Mohamad Fahmi Alatas; Feni Fitriani Taufik; Dewi Yennita Sari; Dicky Soehardiman; Andika Chandra Putra; Erlang Samoedro; Ibrahim Nur Insan Putra Darmawan; Hera Afidjati; Muhammad Alkaff; Rita Rogayah
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.185

Background: Coronavirus disease 2019 (COVID-19) may cause dysregulation of the immune system, leading to hyperinflammation. Inflammatory markers can be used to predict in-hospital mortality in COVID-19 patients. This research was aimed to investigate the association between the levels of various inflammatory markers and mortality in COVID-19 patients.Methods: This study was conducted at Persahabatan National Respiratory Referral Hospital, Indonesia. Blood tests were performed upon admission, measuring the C-reactive protein, PCT, leukocyte, differential counts, and platelet count. The outcome measured was the mortality of hospitalized COVID-19 patients. Statistical analysis methods included the Mann–Whitney U test, receiver operating characteristic (ROC) analysis, and area under the curve (AUC) test.Results: Total 110 patients were included, and the laboratory values were analyzed to compare survivors and non-survivors. The non-survivor group had significantly higher leukocyte count, lower lymphocyte count, higher CRP and PCT levels, higher neutrophil-to-lymphocyte ratio (NLR), higher platelet-to-lymphocyte ratio (PLR), and lower lymphocyte-to-CRP ratio. As predictors of mortality, AUC analysis revealed that PCT, CRP, NLR, and PLR had AUCs of 0.867, 0.82, 0.791, and 0.746, respectively.Conclusions: Routine and affordable inflammatory markers tested on admission may be useful as predictors of in-hospital mortality in COVID-19 patients requiring hospitalization.

Breath Failure in Obesity Wirya Sastra Amran; Putri Suci; Nina Aspiah; Menaldi Rasmin; Prasenohadi Prasenohadi; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 38, No 2 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i2.167

Based on calculations of over one million people in the world weighing excessively or known as obesity with body mass index (IMT) 25 kg / m2 or more. Obesity is the cause of morbidity, as is the case in the population of the United States an estimated 400,000 deaths caused due to obesity. Obesity especially abdominal obesity is a significant risk factor for cardiovascular diseases, type 2 diabetes, rheumatoid arthritis and cancer. The relationship between obesity and chronic respiratory illness began to increase and began to be recognized. The World Health Organization (WHO) predicts about 10% of the global population will be obese by 2015. (J Respir Indo 2018; 38(2): 123-33)

The Association of Working Duration with Lung Function and Chest X-Ray Results in Ceramic Industry Workers of Company X, Mabar Medan Marini Puspita Sari; Amira P Tarigan; Nuryunita Nainggolan; Putri C Eyanoer; Agus Dwi Susanto; Erlangga Samoedro; Caecilia Marliana
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.158

Background: Ceramics industry workers are often exposed to silica materials from ceramics. The aim of this study was to determine the association between silica exposure withlung function test and chest x-ray (CXR) results of the workers. Methods: This was an analytical study with cross-sectional design conducted in the Ceramic Industry X in Mabar, Medan City. The dust level in the work station was measured using Personal Dust Sampler. Lung function was measured by spirometry and CXR was evaluated using the ILO interpretations. Results: About 35 male workers were included as subjects, divided into 3 working stations namely precompression section of 11 subjects (31.4%), compression section of 13 subjects (37.1%) and 11 subjects (31.4%) in the sintering section. Dust levels in each work location are 24.8, 29.2, and 6.11 respectively. Of all subjects, 9 (25.7%) had respiratory symptoms, 21 (60%) had restriction in lung function and 8 (22.8%) had abnormal CXR (6 pneumoconiosis and 2 tuberculosis). There were no association between dust levels with lung function and CXR (P>0.05), but there was a significant correlation between duration of work with lung function. The FEV1 and FVC values of subjects working

Pulmonary Health of Traffic Policemen in Low Air-Polluted Bogor Area Harris Abdullah; Jamal Zaini; Budhi Antariksa; Agus Dwi Susanto; Faisal Yunus
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.183

Background: Traffic policemen are very susceptible to respiratory problems due to the potential for exposure to air pollution. Therefore, this study aimed to assess respiratory health aspects of traffic policemen in Bogor, West Java. Method: Registered traffic policemen in Bogor were evaluated for respiratory symptoms, smoking habits, Fagerström Test for Nicotine Dependence (FTND) Questionnaire, chest x-ray, and spirometry. Air quality measurements were also carried out as a reference. Result: During the study period, the air quality in Bogor was classified as “Good” and below the ambient air pollutant standard. A total of 95 traffic policemen participated with a mean age of 37.3±8.7 years (range 23–57 years), mean Body Mass Index (BMI) of 28.1±4.2 kg/m2, and a length of service of 3-38 years (mean of 12.3 years). Mild pulmonary function impairment was found in 7.4% of subjects. About 61% of subjects had a smoking habit but with a low addiction index (FTND) and exCO. Decreased lung function was correlated to BMI and age (P<0.05). Conclusion: Pulmonary function impairment in traffic policemen in Bogor City was correlated to age and BMI.

Problems of Chronic Obstructive Pulmonary Disease (COPD) Among Workers Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.148

Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. Occupational exposure as a one of important risk factor that contribute for COPD on nonsmoker patients. Several studies at population consistent showed that COPD correlated with hazards exposure at work place. COPD among workers can decrease quality of life, increase of work impairment, work disability and hospitalitation also increase of abstinentia from work and decrease of work productivity. Prevention were major action to prevent incident and morbidity of COPD among workers. Prevention programs including primary, secondary and tertiary prevention.

Comparison Between The Effect of Clove, Filter and Biomass Cigarette Smoke to The Lung Function of COPD Patients at Harum Melati Pringsewu Clinic Lampung Province, Period January 2013-January 2020 Retno Ariza S Soemarwoto; Hetti Rusmini; Fransisca Sinaga; Agus Dwi Susanto; Arif Widiyantoro
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.153

Background: Chronic Obstructive Pulmonary Disease (COPD) is a common disease characterized by respiratory symptoms and limited air flow associated with the airways and/or alveolar abnormalities triggered by a significant effect on substances or gases. COPD is the leading of death cause in the world. COPD can be caused by cigarette smoke and biomass. Method: This research is aquantitative method with descriptive analytic and retrospective approach. The samples were 203 COPD patients taken from medical records January 2013-January 2020 at Harum Melati Pringsewu Clinic Lampung Province with statistical test use Analysis Varians (ANOVA) technique. Results: From the characteristics based on type of COPD smoke exposure were clove smokers 127 people (62.6%), filter smokers 3 people (1.5%) and biomass users 73 people (36.0%). The mean lung function COPD patients based on type of smoke exposure were 127 people with clove smokers with average lung function value 55.03%, the lowest value 12.20% and the highest 121.50%. Filter smokers of 3 people with average lung function value 75.07%, the lowest value was 67.00% and the highest 81.41%. Biomass users 73 people with average lung function value 56.91%, the lowest value 19.50% and the highest 149.13%. Comparison the effect clove cigarettes smoke, filter cigarettes and biomass on the pulmonary function of COPD patients obtained P=0.319. Conclusion: There is a decrease lung function in clove smokers, filter smokers and biomass users in COPD patients but not statistically significant difference.

Respiratory Disorders and Lung Function Impairments of the Scavengers in Bantar Gebang, Bekasi Dita Kurnia Sanie; Agus Dwi Susanto; Fahrial Harahap
Jurnal Respirologi Indonesia Vol 39, No 2 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i2.54

Background: The workers in the landfill have high risk of health problems. The prevalence of respiratory disorders and lung function increases in waste collection workers. There has been no data on respiratory disorders and lung function in scavengers, especially in Bantar Gebang, Bekasi. Methods: This study used a cross-sectional design to the scavengers who work and live in Ciketing Udik, Bantar Gebang, Bekasi. Conducted in January-March 2015, doing interview with questionnaires, and spirometry examination. Results: The number of samples that suitable with the inclusion criteria are 108 subjects. Respiratory disorders are 92 subjects (85.2%). The respiratory disorders consist of 73 subjects with chronic cough, 65 subjects due to shortness of breath, 57 with phlegm and 19 wheezing. Lung function impairments consist of 18 (16.7%) subjects in the form of mild obstruction 3 (2.8%) subjects, mild restriction 11 (10.2%) subjects and mixed 4 (2.8%) subjects. Results of the analysis show that there is a significant relationship between duration of working with respiratory disorders and lung function impairments. Conclusion: There is respiratory disorders and lung function impairments of the scavengers in Bantar Gebang, Bekasi. (J Respir Indo 2019; 39(2): 70-8)

Co-Authors Achmad Hudoyo Adityo Wibowo Agustin, Heidy Ahmad Hudoyo Airin Aldiani Alfiyyah, Arifah Amien, Bagus Radityo Amira P Tarigan Anna Rozaliyani Anna Yusrika Arief Riadi Arifin Arif Widiyantoro Arifin Nawas Ary Indriana Savitri Ayesya Nasta Lestari Ayuningtyas, Putu Duhita Bagus Radityo Amien Bahtiar Husain Bambang Dwi Hasto Budhi Antariksa Budi Prasetyo Caecilia Marliana Caecilia Marliana Deva Bachtiar Dewi Yennita Sari Dita Kurnia Sanie Dita Kurnia Sanie Dita Kurnia Sanie Djasri , Hanevi Erlina Burhan Erlina Burhan Fahrial Harahap Fahrial Harahap Faisal Yunus Faisal Yunus Faisal Yunus Faiza Hatim Falah Kartikawati Farhan Hilmi Taufikulhakim Feni Fitriani Feni Fitriani Fransisca Sinaga Galoeh Adyasiwi Ginting, Tribowo Tuahta Habibi, Januar Hario Baskoro Harris Abdullah Haruyuki Dewi Faisal Hayati, Mulida Hera Afidjati Herman Suryatama Hetti Rusmini Ibrahim Nur Insan Putra Darmawan INDRA YOVI Indy Larasati Wardhana Isbaniah, Fathiyah Isti Mardiana Soetartio Kemas Rakhmat Notariza Khairunnisa Imaduddin Kristianto, Kiki Kurniawidjaja, Meily Lestari, Fetrina Malsephira Hasmeryasih Marini Puspita Sari Maylani, Lina Mega Juliana Menaldi Rasmin Mia Elhidsi Mirza Purwitasari Mohamad Fahmi Alatas Momon, Ade Muchtarrudin Mansyur Muhammad Alkaff Muhammad Ilyas Mukhtar Ikhsan Nalapraya , Widhy Yudistira Nesia Priandari Nina Aspiah Nina Ratu Nur Kharima Notariza, Kemas Rakhmat Nury Nusdwinuringtyas Nuryunita Nainggolan Prasenohadi Prasenohadi Putra, Andika Chandra Putri C Eyanoer Putri Suci Putri Suci Ramadhany Ratnawati Ratnawati Retno A S Soemarwoto Retno Ariza S Soemarwoto Rita Rogayah Rita Rogayah Robiana Modjo Rudi Kurniawan Rudy Satriawan Ruswhandi M Samoedro, Erlang Satria Pratama Seira Putri Boru Rambe Septauli, Kolanda Maria Sita Andarini Sita Laksmi Andarini Siti Chandra Widjanantie Soehardiman, Dicky Sri Wening Pamungkasningsih Syafruddin AR Lelosutan Syazili Mustofa Taufik, Feni Fitriani Thariq Emyl Taufik Hasibuan Tri Apriliawan Bendarto Rahardjo Tugas Ratmono Wahyu Antono Wahyuni, Hendra Widjanantie, Siti Chandra Wirya Sastra Amran Zaini, Jamal

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