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BEBERAPA FAKTOR RISIKO YANG BERPENGARUH TERHADAP KEJADIAN STROKE NON HEMORAGIK (STUDI KASUS DI STROKE CENTER RUMAH SAKIT KHUSUS DAERAH PROPINSI SULAWESI SELATAN) ., Nildawati; Hadisaputro, Suharyo; Samekto, Widiastuti
Jurnal Kesehatan Vol 7, No 2 (2014): Jurnal Kesehatan
Publisher : Kesehatan Masyarakat UIN Alauddin Makassar

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Stroke non hemoragik masih menjadi masalah kesehatan masyarakat, berkaitan dengan tingginya angka morbiditas, mortalitas dan disability. Data tahun 2009 menunjukkan bahwa jumlah kunjungan Stroke non hemoragik di RS khusus daerah Propinsi Sulawesi Se-latan mencapai 890. Tujuan Penelitian ini adalah untuk mengetahui beberapa faktor risiko yang berpengaruh terhadap kejadian stroke non hemoragik.Metode Case Control Study dimana kasus adalah pasien stroke non hemoragik yang berkunjung di Stroke Center Rumah Sakit Khusus Daerah Propinsi Sulawesi Selatan antara kurun waktu Januari 2011 hingga April 2012, sedangkan kontrol adalah pasien yang pernah dan sedang dirawat inap dari bangsal penyakit dalam, dalam kurun waktu yang sama dengan kelompok kasus. Data diperoleh dari buku register, catatan medis, serta dilakukan indepth interview.Hasil analisis multivariat menunjukkan bahwa faktor risiko yang terbukti berpengaruh terhadap kejadian stroke non hemoragik adalah riwayat penyakit dalam keluarga (p = 0,004, OR = 3,6, 95%CI = 1,5-8,9), kebiasaan mengkonsumsi alkohol/ballo (p = 0,004, OR = 4,9, 95%CI = 1,8-13,3), stressor psikososial (p = 0,050, OR = 2,9, 95%CI = 1,0-7,9), pola perilaku (p = 0,004, OR = 5,1, 95%CI = 1,7-15,7), diabetes mellitus (p = 0,000, OR = 5,6, 95%CI = 2,5-12,9%), penyakit jantung (p = 0,011, OR = 3,7, 95%CI = 1,3-9,9), dan kebia-saan mengkonsumsi daging (p = 0,008, OR = 6,0, 95%CI = 1,5-22,7).Faktor risiko yang terbukti secara signifikan adalah riwayat penyakit dalam keluarga, kebiasaan mengkonsumsi alkohol, stressor psikososial, pola perilaku tipe A, diabates melli-tus, kelainan jantung, serta kebiasaan mengkonsumsi daging. Perilaku hidup sehat dengan tidak mengkonsumsi alkohol, olah raga secara teratur, makan makanan yang sehat dan kon-sumsi kolesterol yang berimbang serta tidak stress merupakan faktor penting untuk mencegah terjadinya stroke non hemoragik.Kata kunci : Stroke Non Hemoragik, Faktor-Faktor Risiko, Kasus Kontrol.
Prevention and control of Typhoid fever Hadisaputro, Suharyo
Medical Journal of Indonesia Vol 7 (1998): Supplement 1
Publisher : Faculty of Medicine Universitas Indonesia

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[no abstract available]
Study of Family Behavior that At Risk For Pneumonia in Under Five Children in Mempawah District Rahardjani, Kamilah Budhi; Sakundarno, Mateus; Meilantika, Ayu Diana; Hadisaputro, Suharyo; Mexitalia, Maria
Health Notions Vol 2 No 4 (2018): April 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Pneumonia is respiratory infection disease which effects lungs and there are many cases on under five children. Prevalence period of pneumonia case in Mempawah district the fourth highest of 3.6% of other districts. The purpose of this study was to prove family behavior that are risk of pneumonia in under five children in Mempawah district. This study used case control design. Subject of the study was 100 respondents which consisted of 50 cases and 50 controls meeting the criteria of inclusion. This research use consecutive sampling techniques. Data analysis uses logistic regression. Data were analysed by logistic regression method. Result of analysis shows that history of not exclusive breastfeeding (OR=11.391; 95%CI: 3.087-42.028), habits of not opening room windows (OR= 9.528; 95%CI: 2.699-33.640), existence of pets (OR= 7.871; 95%CI: 2.381-26.019) dwelling density (OR=6.623; 95%CI=1.770-24.785) are proven as risk factors of pneumonia in under five children. Family behaviors as history of not exclusive breastfeeding, habits of not opening room windows, existence of pets, and dwelling density are proven as risk factors of pneumonia in under five children. Keywords: Family behavior, Pneumonia, Under five children
Faktor Risiko Penyakit Ginjal Kronik Diabetes (PGK-DM) pada Diabetes Mellitus Tipe-2 (Studi di RSUD DR Soedarso Kota Pontianak Provinsi Kalimantan Barat) Rini, Sulistio; Hadisaputro, Suharyo; Lestariningsih, Lestariningsih; Nugroho, Heri; Budijitno, Selamat
Jurnal Epidemiologi Kesehatan Komunitas Vol 3, No 1: Februari 2018
Publisher : Sekolah Pascasarjana Universitas Diponegoro Semarang

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Background: Prevalence of type-2 diabetes mellitus have increased significantly. The increasing number of people with diabetes has a major impact on the development of chronic diabetic kidney disease. The research was aimed to clarify several risk factors of chronic diabetic kidney disease on type-2 diabetes mellitus (CDK-DM).Method: The research was based on case control study design. The number of respondents was 140 respondents consisting 70 cases and 70 controls that met the criteria of inclusion and exclusion. The cases were patients with type-2 chronic diabetic kidney disease stadium 2-5. The controls were patients with type-2 chronic diabetic kidney disease with blood sugar levels ≥ 200 mg/dL. The data were then analyzed using logistic regression.Results: The result shows that risk factors of chronic diabetic kidney disease in type-2 diabetes mellitus are diabetes in family (OR = 6,732; 95% CI = 2,623- 17,276), high blood pressure (OR =6,760; 95% CI = 2,190- 20,867), lack of physical activities (OR = 4,367 95% CI = 1,823-10,462) and lack of family support (OR = 4,203; 95% CI = 1,437-12,295). The probability of chronic diabetic kidney disease occurrence in type-2 diabetes mellitus when four risk factors exist are96,71%.Conclusion: The host factors have important role of chronic diabetic kidney disease in type 2 diabetes mellitus . The factors proven to be risk factors for occurrence of chronic diabetic kidney disease in type 2 diabetes mellitus were diabetic in the family, Hipertension, poor physical exercise and family Support.
Effect of zinc supplementation on triglyceride and malondialdehyde levels: study on diabetic Wistar rats induced with streptozotocin Ryadinency, Resty; Hadisaputro, Suharyo; Rachmawati, Banundari
Medical Journal of Indonesia Vol 27, No 2 (2018): June
Publisher : Faculty of Medicine Universitas Indonesia

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Background: Diabetes mellitus is associated with increased blood glucose and triglyceride levels, which can lead to an oxidative stress. Zinc (Zn) is a micronutrient that has antioxidant properties and involved in lipid and glucose metabolism. This study aimed to evaluate the effect of zinc on the levels of fasting blood glucose (FBG), triglycerides (TG), and malondialdehyde (MDA) in male diabetic Rattus norvegicus Wistar rats.Methods: Diabetes was induced by intraperitoneal (i.p.) injection of 40 mg/kg BW streptozotocin (STZ) and confirmed by FBG level higher than 200 mg/dL after 2 weeks. The rats were randomly divided into three groups: control group (STZ), treatment I (STZ + zinc 5 mg/kg BW), and treatment II (STZ + zinc 10 mg/kg BW). Zinc was administered by oral gavage for 30 days. At the end of the experiment, levels of FBG, TG, and MDA were measured. Data were analyzed using paired t-test or Wilcoxon test as appropriate.Results: Supplementation of 5 mg/kg zinc significantly decreased the levels of FBG (pre-intervention: 328.95±70.90 mg/dL, post-intervention: 144.35±34.27 mg/dL, p<0.05), TG (pre-intervention: 252.48±26.30 mg/dL, post-intervention: 147.90±12.18 mg/dL, p<0.05), and MDA (pre-intervention: 12.11±6.46 nm/mL, post-intervention: 4.75±2.34 nm/mL, p<0.05). Moreover, supplementation of 10 mg/kg zinc decreased the levels of TG (pre-intervention: 275.62±56.25nm/mL, post-intervention: 165.58±22.63 nm/mL, p<0.05) and MDA (pre-intervention: 13.08±6.60 nm/mL, post-intervention: 5.08±2.40 nm/mL, p<0.05).Conclusion: Supplementation of zinc significantly reduced the levels of FBG, TG, and MDA in diabetic rats.
Potential of garlic (Allium sativum) essence in changing blood lipid profile of hypertension patients with hypercholesterolemia Hadi, Hadi; Hadisaputro, Suharyo; Ramlan, Djamaluddin
Global Health Management Journal Vol 3, No 1 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: As like hypertension, hypercholesterolemia is a major risk factor for cardiovascular disease and hypertension and its complications are one of the highest causes of death in the world.Aims: This study aims to determine the potential of garlic essence (Allium sativum) mixed with honey in changing blood pressure and lipid profile of blood in the hypertension patients with hypercholesterolemia, and to compare the effectiveness with those who received Simvastatin, the most preferred pharmacological treatment of hyperlipidemia.Methods: This research is a quasy experiment study with a Nonequivalent control group design. There were 22 hypercholesterolemia outpatients purposively selected from local health centers. The respondents were then divided equally to (a) a control group where the patients were provided with generic Simvastatin 10 mg single dose taken once in the afternoon, and (b) an intervention group where the respondents received a non-pharmacological supplement of garlic essence in 2 grams honey. The blood pressure and the blood lipid profile were examined before (Pretest) and at the Day 22 after the treatment (Posttest). The collected data was then analyzed using a T-test to define the significant mean difference between two groups, and a Cohen’s effect was measured to interpret the size of changes.Results: Either the additions of Simvastatin or the provision of garlic essence mixed with honey decreased the blood pressure (systole and diastole) and the cholesterol, triglyceride, and LDL cholesterol, but increased the HDL cholesterol. While significant difference was observed for all parameters at the intervention group, the improvement at the control group for triglyceride was not significant (p value = 0.041). Overall, by the Cohen's effect size effect, we can interpret that the changes was moderate for diastole and systole blood pressure, and also triglyceride and DLD-cholesterol; however the effect size was low for Cholesterol and HDL-cholesterol. Conclusion: The findings show the importance of the garlic essence mixed with honey to be offered as a nutritional supplement for hypertensive patients with hypercholesterolemia.  Keywords: Garlic (Allium sativum) essence, Simvastatin, Hypertension, Hypercholesterolemia, Blood pressure, Blood lipid profile.
The effect of chocolate consumption (Theobroma cacao L.) on level of blood cholesterol and triglyceride in hypertension patients at Jatiroto Health Center, Indonesia Ulkhasanah, Muzaroah Ermawati; Hadisaputro, Suharyo; Pujiastuti, Rr. Sri Endang
Global Health Management Journal Vol 3, No 1 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Hypertension is influenced by lifestyle factors such as high fat intake which has the potential for high blood cholesterol level. Cocoa products, which are rich sources of flavonoids, have been shown to reduce blood pressure and the risk of cardiovascular disease.Aims: The purpose of this research is to examine the dark chocolate consumption in decreasing the level of blood cholesterol and triglyceride in hypertension patients.Methods: This research is a quasi-experiment study with pre and post and control group design. There were thirty two (32) hypertensive patients selected from Jatiroto Health Center in June-July 2018 using a random sampling technique. The respondents were then divided to (1) a control group where patients were prescribed to a popular non-pharmacological therapy Simvastatin and (2) an intervention group where the respondents were prescribed with Simvastatin and also received an additional dark chocolate 60gr/day (given twice a day, each 30gr) for 15 days. A spectrophotometer glycerol phosphate oxidase (GPO-POD) with 546 nm wavelength was employed to measure the levels of blood cholesterol and triglyceride. The significant mean difference between pre and posttest, and the changes between control and intervention group were defined by statistical analysis T-test.Results: This study acknowledged that the prescribed simvastatin alone presents a significant contribution to decrease the cholesterol level at 14.40 point (p value = 0.041), however, the generic is not enough to deliver a significant effect to the decrease of triglyceride level in the hypertension patients (p value = 0.361). A great contribution to the depression of cholesterol and triglyceride level in the hypertensive respondent was observed if simvastatin prescription was combined with a provision of 60 gram dark chocolate, respectively to the level of 57.06 and 38.41 mg/dL with p value = 0.001. The addition of dark chocolate in the simvastatin prescription will significantly reduce the blood cholesterol level (p value = 0.020), but not really effective to reduce the triglyceride (p value = 0.560).Conclusion: The findings suggest that giving dark chocolate to the hypertensive patients who receive simvastatin prescription will decrease the cholesterol and triglyceride levels greater than the consumption of simvastatin drugs alone. Keywords: Dark chocolate, Simvastatin, Hypertension, Cholesterol, Triglyceride
The Effect of Snake Fish Extract (Channa striata) on Post Cesarean Section Wound Status in Postpartum Anemia Mothers Fajri, Umi Nur; Hadisaputro, Suharyo; Soejoenoes, Ariawan
Indonesian Journal of Medicine Vol 3, No 2 (2018)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: A labor with Sectio Caesarea (SC) will increase mortality rate, which is twice the rate of vaginal delivery. The morbidity rate is also higher in SC delivery due to post-SC wound infection. Post-SC wound healing requires high albumin. This study is intended to determine the effect of snake fish extract on post-SC wound status in postpartum anemia women.Subjects and Method: This was a true experimental study with randomized control group post-test design. The study was conducted at Hj. Anna Lasmanah Hospital, Banjarnegara, Central Java, in May to June 2018. The population of all post-partum postpartum mothers was anemia. A sample of 30 study subjects was selected by stratified random sampling, consisted of 15 study subjects in intervention and control groups. The dependent variable was post-SC wound. The independent variable was snake fish extract. Post-SC wound was measured by REEDA scales. The data was analyzed by General Linear Model Repeated Measure.Results: In day-5, post-SC wound in the intervention group (mean= 0.27; SD= 0.46) was lower than control group (mean= 1.07; SD= 0.80) and it was statistically significant (p= 0.002).Conclusion: Channa striata extract can accelerate post-SC wound healing.Keywords: Channa striata extract, wound status, sectio caesarea, anemiaCorrespondence:Umi Nur Fajri. Applied Midwifery, Graduate Program, School of Health Polytechnics, Ministry of Health Semarang. Email: nurfajriumie@yahoo.co.id. Mobile: 085214594590.Indonesian Journal of Medicine (2018), 3(2): 84-88https://doi.org/10.26911/theijmed.2018.03.02.04
The Effect of Lactapuncture Massage on Breast Milk Production through Prolactin Hormone Levels Changes in Dr. M. Ashari Hospital, Pemalang, Central Java Patimah, Siti; Mashoedi, Imam Djamaluddin; Hadisaputro, Suharyo
Indonesian Journal of Medicine Vol 4, No 1 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Problems that inhibit breastfeeding in the first week include less breast milk production. Increasing breast milk production can be done by stimulating or massage the breast. Breast massage can be done by lactapuncture massage. This study aimed to examine the effect of lactapuncture massage on prolactin hormone levels and breast milk production among primiparous mothers.Subjects and Method: This was a quasy experiment study conducted at Dr. M. Ashari hospital, Pemalang, Central Java, Indonesia. A sample of 32 primiparous postpartum mothers was selected by simple random sampling. The dependent variable was breast milk production. The independent variables were lactapuncture massage for 7 consecutive days. The data were analyzed by t-test.Results: Prolactin hormone level in intervention group (mean= 313.80; SD= 45.54) was higher than in control group (mean= 292.09; SD= 97.87) but it was statistically non-significant (p= 0.428). Breast milk production in intervention group was higher (mean= 9.36; SD= 0.71) than in control group (mean= 7.39; SD= 0.23) and it was statistically significant (p<0.001).Conclusion: The lactapuncture massage on 2-3 times clockwise at each point for 7 consecutive days increasing prolactin hormone levels and on breast milk production.Keywords: lactapuncture massage, prolactin hormone, breast milk productionCorrespondence: Siti Patimah. Applied Midwifery, Graduate Program, School of Health Polytechnics, Ministry of Health Semarang. Email: imafatimah922@gmail.com. Mobile: 081329283952 Indonesian Journal of Medicine (2019), 4(1): 15-20https://doi.org/10.26911/theijmed.2019.04.01.03
Yoga Increases the Quality of Sleep in Menopause Women Fara, Yetty Dwi; Pujiastuti, Rr. Sri Endang; Hadisaputro, Suharyo
Indonesian Journal of Medicine Vol 4, No 3 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Menopausal women expe­rience various changes, physical, psycho­logical, and hormonal changes that cause menopausal symptoms. During menopause, women experience sleep disorders and some experience insomnia. Lifestyle changes are one way to reduce menopausal symptoms, such as physical activity. Physical activities such as yoga can stimulate a relaxation response both physically and psychologically that can reduce physical and psychological symptoms in menopausal women. The aim of this study was to examine the effect of yoga interventions on the sleep quality of menopausal women.Subjects and Method: This was a quasi-experiment with a non-equivalent control group design. The study was conducted in the Gedawang-Banyumanik area, Semarang, Central Java. A total of 22 study subjects was collected by purposive sampling. The dependent variable was the quality of sleep. The independent variable was yoga. The quality of sleep was measured using the Pittsburgh Sleep Quality Index (PSQI).Results: Poor quality of sleep score decreased by 10.73 after yoga intervention (95% CI= -4.30 to -0.26; p= 0.029).Conclusion: Yoga interventions improve the quality of sleep in menopausal women.Keywords: quality of sleep, yoga, menopausal womenCorrespondence: Yetty Dwi Fara. Midwifery Program, School of Health Polytechnics Semarang. Jl. Tirto Agung Pedalangan, Banyumanik, Semarang, Central Java, 50239. Email: yettydwifara@gmail.com. Mobile: 085279545189.Indonesian Journal of Medicine (2019), 4(3): 278-284https://doi.org/10.26911/theijmed.2019.04.03.11
Co-Authors Abdul Ghofur Adam, Oktaviana Thresia Monika Barbara Ag Soemantri Agus Suwandono Agustinus Soemantri Amin, Dewita Rahmatul Andriana, Andriana - Ani Margawati Anies Anies Anies Annastasia Ediati Arfan, Iskandar Ari Budi Himawan Ari Suwondo Aris Santjaka Astuti, Ismi Puji Awan Hariyanto, Awan Ayu Diana Meilantika Bagoes Widjanarko Banundari Rachmawati Dilla, Tasya Nurlaila Diyah Fatmasari Djamaluddin Ramlan, Djamaluddin Djokomoeljanto Djokomoeljanto Dwi Pudjonarko Eny Retna Ambarwati Fajri, Umi Nur Fara, Yetty Dwi Farah Salsabila, Farah Ganda Gumilar, Argo Gumilar, Argo Ganda Gustiya, Sherly Dwi Hadi Hadi Hamdan, Yusuf Lensa Harfaina, Harfaina Haryono, Nathasia Elga Henry Setyawan Susanto Henry Setyawan Susanto Heri Nugroho Herliani, Emy Herman Kristanto Hikmah, Kholisotul Imam Djamaluddin Mashoedi Iswari Setianingsih Jaleha, Jaleha Jayawarsa, A.A. Ketut Julian Dewantiningrum K. Heri Nugroho HS, K. Heri Kamilah Budhi Rahardjani, Kamilah Budhi Khabib Mualim, Khabib Kumorwulan, Suryati Kurniawati, Erna Yovi Lestariningsih Lestariningsih Lukmono, Djoko Trihadi Maria Mexitalia Mateus Sakundarno Adi, Mateus Sakundarno Melyana Nurul Widyawati Moedrik Tamam Muflihah Isnawati Muhammad Saleh Muliawati, Ratna Muzaroah Ermawati Ulkhasanah Nildawati . Noor Pramono Nur Djanah, Nur Nurjanah, Fatihah Wari Nurul Aeni Oktavia, Eva Zuli Oktaviarini, Eka Onny Setiani Pratiwi, Tia Purwanti, Sumy Hastry Pusaka, Semerdanta Rahmah, Aulia Agyanti Resty Ryadinency Rini Astuti Rini, Sulistio Roesipin, Sri Wahyuningsih Rr. Sri Endang Pujiastuti Salma, Baiq Desi Sayono Sayono Selamat Budijitno Shofa Chasani Siti Patimah Soejoenoes, Ariawan Soejoenoes, Ariawan Sofro, Muchlis AU SRI RAHAYU Sri Sumarni Sri Wahyuni Sudiyono Suprihati - Supriyadi - Supriyana Supriyana, Supriyana Suryati Kumorowulan Sutaryo Sutaryo Thaariq, Nurul Aziza Ath Tjokorda Gde Dalem Pemayun Triana Sri Hardjanti, Triana Sri Untung Sujianto Widiastuti Samekto Widjarnarko, Bagoes Yunie Armiyati