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Hubungan Ekspresi Her-2/Neu, Skor Gleason dan Metastasis Tulang pada Adenokarsinoma Prostat Nina Mardiana; Imam Susilo
Majalah Patologi Indonesia Vol 22 No 2 (2013): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (432.697 KB)

Abstract

ABSTRAK Latarbelakang Prediksi sifat biologik adenokarsinoma prostat masih menjadi masalah. Umumnya, kanker prostat tidak menimbulkan keluhan (asimtomatik) walaupun kadang-kadang sudah ada metastasis. Oleh karena itu, dibutuhkan parameter yang bisa dipakai sebagai faktor prognostik sehingga pendekatan terapi bisa lebih tepat. Penelitian ini menganalisis hubungan ekspresi Her-2/Neu dan skor Gleason dengan kejadian metastasis tulang. Metode Penilaian dilakukan terhadap blok parafin penderita adenokarsinoma prostat yang didiagnosis di RSUD. Dr. Soetomo mulai Januari 2009-Mei 2012 dan memenuhi kriteria, sebanyak total 28 sampel. Kemudian dilakukan analisis hubungan masing-masing variabel dengan uji Spearman dan Chi Square. Hasil Ekspresi Her-2/Neu terbesar ialah kategori negatif (16/28 kasus). Sebagian besar kanker berdiferensiasi rendah (17/28 kasus). Jumlah sampel dengan metastasis 16/28 kasus. Uji hubungan antara ekspresi Her-2/Neu dan skor Gleason, antara ekspresi Her-2/Neu dan metastasis serta antara skor Gleason dan metastasis menunjukkan hubungan yang tidak bermakna. Kesimpulan Terdapat hubungan yang tidak bermakna antara ekspresi Her-2/Neu, skor Gleason dan kejadian metastasis tulang pada adenokarsinoma prostat. Kata kunci : adenokarsinoma prostat, ekspresi Her-2/Neu, skor Gleason, metastasis tulang. ABSTRACT Background Prediction of prostate adenocarcinoma biological behavior is still a problem. Generally, prostate cancersdo not cause complaints although some times there arealready metastasized. Therefore, parameters are required which can be usedas prognostic factorsso that therapeutic approaches can be more precise. This study analyzed the correlation of Her-2/Neu expression, Gleason’sscore and the incidence of bone metastases. Methods Assessment was performed on paraffin blocks of prostate adenocarcinoma patients who were diagnosed in Dr. Soetomo hospital during January 2009-May 2012 and met the criteria, with a total of 28 samples. Each variable was analyzed with the Spearman and Chi Square test. Results Expression of Her-2/Neu was mostly included in the negative category (16/28 cases). Most of the cancers showed low differentiation or high grade (17/28 cases). The number of metastases was 16/28 cases. Statistical test which assa the relationship between expression of Her-2/Neu and Gleason’s score, between HER-2/Neu expression and metastasisas well as the Gleason’s score and metastasis showed no significant correlation. Conclusion There was no significant correlation between the expression of Her2/Neu, Gleason’s scoreand the incidence of bone metastases in prostate adenocarcinoma. Key words : Adenocarcinoma of the prostate, Her-2/Neu expression, Gleason’s score, bone metastases.
The Effect of Chilbirth Gymnastic Towards Physiological Change on Post-Partum Mother Day I-III in Balikpapan Maternity Clinic Sonya Yulia; Nina Mardiana
Health Notions Vol 2, No 10 (2018): October
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn.v2i10.312

Abstract

Maternal Mortality Rate in the world is more than one millions every year; the most significant maternal mortality on childbirth of 49.125% and 50% occurs in the first 24 hours. It can be prevented through childbirth gymnastic because it can help accelerating the physiological change like uterine involution, lochea, defecation, and urination, and breast milk production. This research aims to comprehend the effect of childbirth gymnastic towards post-partum maternal physiological change day I-III. This experimental research used randomized two group design. Samples were selected by purposive sampling (30 for experiment group and 30 for control group). The research instruments were observation check list and interview guide. Data were presented in the form of mean, mode and standard deviation, then analyzed by using independent sample t-test. There was an effect of childbirth gymnastic on uterine involution (p-value 0.000); there was an effect of childbirth gymnastic on lochea change (p-value 0.000); there was childbirth change on defecation change (p-value 0.000) and there was an effect of childbirth gymnastic on breast milk production (p-value 0.000). Keywords: Childbirth gymnastic, Physiological change
FAKTOR YANG BERHUBUNGAN DENGAN SELF EFFICACY DALAM MEMERIKSAKAN KEHAMILAN DI KOTA BALIKPAPAN Nina Mardiana; Grace Carol Sipasulta; Meitty Albertina
MMJ (Mahakam Midwifery Journal) Vol 3 No 2 (2018): Vol. 3 No. 2 November 2018
Publisher : Politeknik Kesehatan Kementerian Kesehatan Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.426 KB) | DOI: 10.35963/midwifery.v3i2.107

Abstract

Abstract In Indonesia, the utilization of antenatal services by health workers is only 66% and this figure decreases during childbirth, where the mother who examined her pregnancy to a health worker did not deliver her labor at a health facility, which amounted to 9.12%. This study aims to explain the relationship between knowledge and intention towards self efficacy of pregnant women in antenatal care in Balikpapan City. This type of research is Quasi Experiment Design with pre and post control group study. The study design used Non Equivalent Control Group. Samples were pregnant women with gestational age are entering the second trimester in Balikpapan City who visited twenty women cases and twenty women are control. The results of the study have a significant relationship between knowledge of Self efficacy P value: 0.043, there is a significant relationship between intention to self efficacy P value: 0.029. The conclusion of this study is that the self efficacy of pregnant women is high, pregnant women are not in high risk age, mothers with high parity and parity are both having high knowledge. There are still pregnant women who have high knowledge but do not have their pregnancies checked on health workers. Most mothers have the intention to have their pregnancies checked on health workers but there are still pregnant women who have their pregnancy checks less than the prescribed standard of at least 4 times during pregnancy. Keywords: Knowledge, Intention, Self efficacy. Abstrak Di Indonesia pemanfaatan pelayanan antenatal oleh tenaga kesehatan hanya 66% dan angka ini menurun saat terjadi persalinan, dimana ibu yang memeriksakan kehamilannya ke tenaga kesehatan tidak melangsungkan persalinannya di fasilitas kesehatan, yaitu sebesar 9,12%. Penelitian ini bertujuan menjelaskan hubungan pengetahuan dan niat terhadap self efficacy ibu hamil dalam pelayanan antenatal di Kota Balikpapan. Jenis penelitian yang adalah penelitian eksperimen semu (Quasi Experiment Design) dengan pre dan post control group study. Rancangan penelitian menggunakan Non Equivalen Control Group.Sampel adalah ibu hamil dengan usia kehamilan memasuki tri mester II yang berada di Kota Balikpapan yang berkunjung ke puskesmas Muara Rapak sebanyak 20 orang dan kontrol ibu hamil sebanyak 20 orang. Hasil penelitian ada hubungan yang signifikan pengetahuan terhadap Self efficacyp-value : 0,043, ada hubungan yang signifikan niat terhadap self efficacyp-value : 0,029. Kesimpulan pada penelitian ini self efficacy ibu hamil tergolong tinggi, ibu hamil tidak dalam usia risiko tinggi, Ibu dengan paritas tinggi maupun paritas sedang sama-sama memiliki pengetahuan tinggi. Masih ada ibu hamil yang memiliki pengetahuan tinggi tetapi tidak memeriksakan kehamilannya pada tenaga kesehatan. Sebagian besar ibu memiliki niat untuk memeriksakan kehamilannya pada tenaga kesehatan tetapi masih ada ibu hamil yang melakukan pemeriksaaan kehamilannya kurang dari standar yang ditentukan yaitu minimal 4 kali selama kehamilan. Kata kunci : Pengetahuan, Niat, Self efficacy.
The Effect of Telecounseling on the Anxiety of Pregnant Women during the COVID-19 Pandemic at the Belusuh Health Center in West Kutai in 2022 Juliati; Nina Mardiana; Gajali Rahman
Formosa Journal of Science and Technology Vol. 2 No. 2 (2023): February 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v2i2.2803

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This study aims to determine the effect of telecounseling on the anxiety of pregnant women during the COVID-19 pandemic. This type of research is a quantitative research with a quasy experimental research design with a one group pre-post test design. The population in this study were pregnant women in the working area of ​​the Belusuh Health Center, totaling 57 people. The sampling technique used was purposive sampling with a total sample of 14 people. Data analysis technique using the Wilcoxon test. Based on the research results obtained, it can be concluded that there is an effect of telecounseling on the anxiety of pregnant women during the COVID-19 pandemic at the Belusuh Kutai Barat Health Center as evidenced by the results of the statistical test p-value 0.001 (< α = 0.05). After attending counseling for pregnant women, they are able to express disturbing feelings and feel relieved and relaxed.
The Effect of Husbands’ Support on Mothers’ Family Planning in Dayak Tribe Evy Nurachma; Nina Mardiana
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 3 (2022): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1185.539 KB) | DOI: 10.55324/ijoms.v2i3.299

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The Dayak tribe has a fairly strong magical heritage. The spiritual sciences became a typical symbol of the tribal customs that inhabited the interior of the land of Borneo. F the factors that hinder the development of birth control are the Supernatural World for Dayak Tribe The leaves of dong quai can be material to prevent pregnancy in a very natural way. but the factor of lack of support from the husband greatly affects the attitude of the mother in the  Dayak tribe environment in using contraceptives, Purpose, knowing the influence of husband support on the attitude of mothers in birth control in Pampang Village. The design of this study is cross sectional. The sample used was 47 respondents. The sampling technique uses purposive sampling. Analisa bivariate using the chi square test.  Most of the mothers in Pampang village had negative attitudes as much as 51.1% and most of their husbands did not support as much as 64.3% and almost half of the respondents participated in family planning as much as 48.9%. A significant relationship between maternal attitudes  and husband support with family planning participation in Pampang Village is shown by p value: 0.002 < ?: 0.05, and p value 0.02 < ?: 0.05.
Attitudes and Supports on Pregnant Women’s Intention in HIV Testing and Breastfeeding Decision Nina Mardiana; Evy Nurachma; Rita Kirana; Yona Polin
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 4 (2023): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (824.807 KB) | DOI: 10.55324/ijoms.v2i4.365

Abstract

HIV/AIDS is a disease caused by a virus that attacks the human body's immunity. It continues to increase from year to year and can transmit the disease from mother to child. More than 9,000 pregnant women with HIV positive status every year and 30% of them give birth to HIV positive babies. The purpose of this study analyzed the attitude, support (husband, health workers, friends) towards the intention of pregnant women to do HIV testing and the decision to breastfeed in the city of Balikpapan. This study used a survey method with a cross-sectional study design. The sampling was applied to 124 people of Puskesmas. Descriptive and analytical data analysis with frequency distribution and PLS (Partial Least Square) were used. The results showed that the youngest pregnant women were 17 years old and the oldest 41 years old, most pregnant women received good support from their husbands, officers and friends by 52.4%, pregnant women had a high intention of conducting an HIV test test of 53.2%. There is a significant relationship: attitude towards the intention of pregnant women to test for HIV and support towards the intention of pregnant women to test for HIV, attitude towards breastfeeding decisions, and support towards breastfeeding decisions, HIV test intentions towards breastfeeding decisions in Balikpapan city. Pregnant women with HIV positive must be disciplined in eating ARV (Anti-Retro Viral) to give breast milk to their babies, health workers must provide counseling and counseling to pregnant women about exclusive breastfeeding or formula milk.
GAMBARAN STATUS GIZI SISWA PUTRI KELAS II SMP PATRA DARMA BALIKPAPAN nina mardiana; Wiryanto Wiryanto
MNJ (Mahakam Nursing Journal) Vol 1 No 1 (2016): Mei 2016
Publisher : Poltekkes Kemenkes Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.247 KB)

Abstract

Abstract East Kalimantan province, including 19 provinces with a prevalence of underweight children of school age (women) above the national prevalence, the national prevalence of underweight children of school age (women) was 10.9%. Nutritional problems in adolescents arise because of the wrong nutritional behaviour, namely the imbalance between nutritional intake with the recommended dietary allowance. A group of teens need to consume a lot of food if the food is not balanced with the need calories for growth and development, there will be a deficiency that could eventually hamper its growth. This study aims to give a picture of the Nutritional Status of Young Women Class II SMP Patra Dharma I Balikpapan. The results of this study were 9 people (19.1%) of young women students of class II SMP Patra Dharma I Balikpapan are in the category of thin, 13 people (27.7%) arm circumference of less than 23.5 cm, the average height between 145.46 to 147.31 cm, and the mean hemoglobin levels between 8.61 to 11.80 g%. The conclusion of this study the nutritional status of adolescent girls class II SPM Patra Darma I Balikpapan still low so it needs strict supervision of parents in terms of healthy eating and giving young women iron tablets. Keywords: Nutritional status of young women, SMP Patra Dharma.
INOVASI BOTOL HISAP MENINGKATKAN PENGETAHUAN DAN SIKAP TENTANG BAHAYA MEROKOK PADA SISWA KELAS X DI SMKN 2 DI SAMARINDA Nouvalia Putri; Nina Mardiana; Dwi Hendriani
Medic Nutricia : Jurnal Ilmu Kesehatan Vol. 9 No. 1 (2024): Medic Nutricia : Jurnal Ilmu Kesehatan
Publisher : Cahaya Ilmu Bangsa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5455/nutricia.v9i1.6492

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Merokok adalah kegiatan membakar tembakau lalu dihisap menggunakan rokok maupun pipa. Perilaku merokok sangat berdampak pada paru-paru, meningkatkan risiko penyakit, dan menurunkan kesehatan perokok secara umum. Persentase merokok pada penduduk usia lebih dari 10 tahun di Kalimantan Timur sebesar 22.3%. Penelitian ini bertujuan untuk mengetahui pengaruh pendidikan kesehatan menggunakan media alat peraga botol hisap sederhana terhadap pengetahuan dan sikap siswa kelas X tentang bahaya merokok di SMKN 2 Samarinda. Jenis penelitian ini adalah quasy eksperiment dengan desain two group pretest postest. Sampel penelitian berjumlah masing-masing 35 siswa dalam kelompok intervensi dan control kelas X. Pengumpulan data melalui pengisian kuesioner. Uji analisis data yang digunakan menggunakan uji Wilcoxon. Hasil penelitian menunjukkan terjadi penambahan jumlah siswa yang memiliki pengetahuan baik dan sikap positif tentang bahaya merokok. Analisis statistika menunjukkan hasil signifikan pada pengetahuan (ρ-value = 0,000) dan sikap (ρ-value = 0,000) remaja tentang bahaya merokok. Sehingga pendidikan kesehatan menggunakan media alat peraga berpengaruh terhadap pengetahuan dan sikap siswa kelas X. Kelompok remaja diharapkan meningkatkan pengetahuan dan sikap mengenai bahaya merokok sejak dini. Orang tua dan guru juga diharapkan berperan aktif dalam membimbing serta mengingatkan remaja tentang bahaya merokok.
Driving Behavior of Online Ojek X towards Safety Driving in Anggana Sub-district Ayyik Busromaqoli; Nina Mardiana; Dian Ardiyanti
Jurnal Kesehatan Masyarakat Indonesia (JKMI) Vol. 2 No. 1 (2024): Oktober
Publisher : Publikasi Inspirasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62017/jkmi.v2i1.2467

Abstract

Abstract Traffic accidents in East Kalimantan, particularly in Anggana District, pose a serious issue. As of October 2023, there have been over 20 cases of minor to moderate accidents involving online motorcycle taxi drivers, often due to the negligence of other road users. This study employs a qualitative method with a case study design, involving 9 informants. Results indicate that the use of Personal Protective Equipment (PPE) by Ojek Online X is rated positively by passengers. Drivers who are healthy and well-rested are motivated by attractive earnings and flexible schedules. Ojek Online X prioritizes quality service through vehicle maintenance to reduce accident risks. A safe working environment is crucial for maintaining a positive public image. In conclusion, good PPE usage, adequate rest, and financial motivation contribute to safety and work quality. These findings can serve as a reference for other online motorcycle taxi drivers in implementing Safety Riding principles.
Efektivitas Peer Group terhadap Konsumsi Tablet Fe pada Remaja Putri Esti Nur Rahayu; Nina Mardiana; Lidia Lushinta
Midwifery Care Journal Vol 5, No 2 (2024): April 2024
Publisher : Politeknik Kesehatan Kementrian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/micajo.v5i2.10055

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The problem encountered was the attitude of not wanting to take Fe tablets with the reason that it was uncomfortable because of the bad smell and taste like iron. The factor of routine consumption of Fe tablets can be encouraged by applying the Peer Group Education method. The purpose of this study was to determine the effectiveness of the Peer Group on increasing the consumption of Fe tablets in adolescent girls. Peer groups is a form of education that emphasizes behavior change and this method interaction occurs within the group. This type of research is a Quasi Experiment with a Non Equivalent Control Group Design. The population in this study were all female students of class VIII at SMP Negeri 4 Samarinda, totaling 190 students. Sampling using the Simple Random Sampling technique with the Mann Whittney U-Test test. 85.7% of respondents were in the effective category, and 100% of the respondents were in the routine category. So that there is the effectiveness of the Peer Group on increasing consumption of Fe tablets (p value = 0.00) with a value of = 0.05. Group education by peers (peer education) is a process of communication, information, and education (IEC) carried out by and for peers through the formation of peer groups. It also functions as a forum for sharing among group members so that teenagers exchange ideas and remind each other about consuming Fe tablets.