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Type IV collagen as marker of fibrosis in nonalcoholic liver disease Alvina, Alvina
Universa Medicina Vol 29, No 2 (2010)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2010.v29.114-122

Abstract

Currently nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are medical problems associated with the increasing prevalence of diabetes mellitus, obesity, hypertension and hypertriglyceridemia, usually designated as the metabolic syndrome associated with insulin resistance. One study demonstrated an increase in NAFLD prevalence of around 17-33% and in NASH prevalence of 5.7-16.5%. NAFLD comprises a range of mild to severe conditions, from simple steatosis to steatohepatitis, hepatic fibrosis and cirrhosis. The diagnosis of hepatic fibrosis is important for prognosis, stratification for treatment, and monitoring of treatment efficacy. Ultrasonography (USG) is a simple method for detecting fatty infiltrates in the liver. USG has a sensitivity of 82-89% and a specificity of 93%, but cannot differentiate between hepatic steatosis and fibrosis. The gold standard for evaluation of hepatic fibrosis is liver biopsy, which however is a painful and invasive procedure. Currently determination of serum type IV collagen has been suggested as an alternative to liver biopsy among the non-invasive methods for evaluation of hepatic fibrosis, as its serum concentration is closely correlated with advanced hepatic fibrosis in NASH. Type IV collagen is one of the components of basement membrane and its serum concentration is indicative of degradation of the extracellular matrix.
Hepatic enzyme concentrations as indicators of nonalcoholic fatty liver disease Alvina, Alvina
Universa Medicina Vol 28, No 3 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.139-145

Abstract

Nonalcoholic fatty liver disease (NAFLD) has emerged as a world-wide problem because it runs an asymptomatic course, ultimately leading to cirrhosis of the liver and portal hypertension, resulting in death. The prevalence of the disease accounts for 3-24% of the population in several countries. Generally there are increased concentrations of hepatic enzymes as markers of liver damage, such as serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and gamma glutamyl transferase (GGT). The aim of the present study was to determine the concentrations of hepatic enzymes as markers of NAFLD. The study design was cross-sectional, involving 90 subjects meeting the inclusion and exclusion criteria. The degree of severity NAFLD was determined by ultrasonography and the concentrations of SGOT, SGPT and GGT by automated clinical chemistry analyzer. The results indicated that there were 32 subjects with mild NAFLD (35.6%), 35 subjects with moderate NAFLD (38.9%) and 23 subjects with severe NAFLD (25.6%). There was a significant difference in degree of NAFLD by gender (p<0.05), where severe NAFLD was more frequent in males than in females. Concentrations of SGOT, SGPT and GGT were significantly different between degrees of NAFLD (p<0.05). The conclusion is that SGOT, SGPT and GGT concentrations are indicators of degree of NAFLD.
Idiopathic thrombocytopenic purpura: laboratory diagnosis and management Alvina, Alvina
Universa Medicina Vol 30, No 2 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.126-134

Abstract

Idiopathic thrombocytopenic purpura (ITP) or immune thrombocytopenic purpura is a disease characterized by low platelet count (<150,000/ìL) caused by autoantibody-mediated platelet destruction and the absence of other causes of thrombocytopenia. Acute primary ITP is more common in children 2-6 years of age, with similar incidence between males and females, while the chronic form is usually encountered in adults with median age of 40-45 years. The clinical signs of ITP are purpura, ecchymosis, petechiae and gastrointestinal tract bleeding, gingival bleeding, epistaxis, and urinary tract bleeding. Spontaneous mucosal, intracranial, and gastrointestinal hemorrhage may occur at platelet counts of <10000/ìL. To date, the diagnosis of ITP is still arrived at by exclusion, i.e. by elimination of other causes of thrombocytopenia. The diagnosis of ITP also requires a medical history (anamnesis), physical examination, platelet count, and examination of a peripheral blood smear. The latter examination in ITP shows low numbers of normal-sized platelets, occasionally also giant platelets, while erythrocytes and leukocytes have a normal morphology. The bone marrow is usually normal or shows increased megakaryocytes. Assessment of antithrombocyte antibody may assist in establishing the diagnosis of ITP. Management of ITP is based on platelet count and severity of bleeding. Treatment is aimed at interfering with antibodies that damage the platelets, by inhibiting the functions of macrophage Fcã receptors and decreasing the production of antiplatelet antibodies. Thrombopoietin (TPO) receptor agonists including eltrombopag and romiplostim have offered an important new option in treating ITP.
Heavy mental workload increase poor sleep quality in informal garment workers Merijanti, Lie T; Pusparini, Pusparini; Meiyanti, Meiyanti; Alvina, Alvina; Sudharma, Novia I; Tjahjadi, Muljadi
Universa Medicina Vol 38, No 3 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (687.632 KB) | DOI: 10.18051/UnivMed.2019.v38.202-208

Abstract

Background Sleep is needed by the human body so that the performance of body remains optimal when the body is awake, especially during work. Informal workers often work without clear regulations, with inadequate equipment and poor work environment, and pay little attention to occupational health and safety factors. The existence of large work demands with unclear work system arrangements will certainly result in a mental workload in these workers. The objective of this study was to determine the relationship between mental workload and sleep patterns of workers in the informal garment sector. MethodsA cross-sectional study involving 225 informal garment workers was conducted between December 2018 and May 2019. Data collection included respondents’ demographics, job characteristics, measurement of mental burden and disturbances in sleep patterns. The sleep pattern used the PSQI (Pittsburgh Sleep Quality Index) instrument and the mental burden used the Rating Scale Mental Effort (RSME). A multiple linear regression analysis was used to analyze the data. ResultsThe mean sleep quality was 5.40 ± 2.54. Multiple linear regression test found that mental workload correlated significantly with sleep quality of workers (β=0.016, p=0.012).ConclusionThis study demonstrated that heavy mental workload decreases the quality of sleep in informal garment workers. A good work system management is required so that workers are assigned that portion of the task that is commensurate with their capacity.
PERBEDAAN MORDAN BELIMBING MANIS (Avverhoa Carambola) DAN BELIMBING WULUH (Avverhoa Bilimbi) TERHADAP HASIL PENCELUPAN PADA BAHAN SUTERA MENGGUNAKAN EKSTRAK BIJI KESUMBA (Bixa Orellana L) Alvina, Alvina; Adriani, Adriani; Novrita, Sri Zulfia
Journal of Home Economics and Tourism Vol 12, No 2 (2016): Priode Mei 2016
Publisher : Faculty of Tourism and Hospitality - Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (832.045 KB)

Abstract

This study aimed to describe the name of the color (hue), light and dark colors (Value) and flatness of color for silk dyeing results using crimson seed extract (Bixa Orellana l) with mordant sweet star fruit and starfruit. This research is an experimental research. The data used are primary data sourced from 15 panelists, then the collected data is processed and analyzed using ANOVA and Percentage. Dyeing silk with crimson seed extract (Bixa Orellana l) without mordant produce Mineral Orange color with a value reasonably bright and flatness of color is quite average. Mordan sweet star fruit is Peach with bright value and average color flatness and mordant starfruit is Light Peach with a value very bright and flatness of color is very flat. The results of the data analysis of light and dark colors (value) indicates F count> F table = 3.320> 3. 22 This means that there is a significant difference to the light and dark colors (value) due to differences mordant. At the flatness of the color indicates Fhitung> Ftable = 9599> 3.22 means that there is a significant difference to the flatness of color due to differences mordant. Kata Kunci : Perbedaan Mordan, Ekstrak Biji Kesumba
Pengaruh Keberadaan Kampus Universitas Islam An Nur Lampung Terhadap Kondisi Ekonomi Masyarakat Desa Sidoharjo Dalam Prespektif Ekonomi Syariah Alvina, Alvina; Efrina, Lisa; Rohmawati, Zulfa
Sharing: Journal of Islamic Economics Management and Business Vol. 3 No. 1 (2024): Juni 2024
Publisher : Program Studi Ekonomi Syariah Fakultas Agama Islam Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sharing.v3i1.26046

Abstract

The point of this examination is to decide the impact of the presence of A Nur Lampung Islamic College on the monetary states of the encompassing local area. The Impact of the Presence of A Nur Lampung Islamic College on the Financial States of the Sidoharjo Town People group in a Sharia Monetary Viewpoint (Contextual investigation of the Sidoharjo Town People group, Jatiagung Locale, South Lampung Rule). The strategy utilized in this exploration is a quantitative examination technique. The number of inhabitants in this study were occupants of Sidoharjo Town who had the situation with Head of Family. Corresponding arbitrary examining method. The example in this study was 25 heads of families spread across two villas in Sidoharjo Town. The information utilized is information on the quantity of family heads (KK) in every villa. The assortment strategy is as documentation and surveys. The information was handled and dissected utilizing the cross organization information examination strategy (crosstab). The exploration results show that the presence of the A Nur Lampung Islamic College grounds for the most part emphatically affects new financial development. In light of the presence of the A Nur Lampung Islamic College people group, financial circumstances should be visible from the synchronous cost assurance coefficient r table. The consequences of the examination acquired a rtable cost of 0.511. In this manner, it shows that the presence of A Nur Lampung Islamic College impacts financial circumstancesWatchwords: Islamic Economics¸ Social Circumstances, College
Asuhan Keperawatan pada Klien Ny. D dan Ny. S yang Mengalami Ketidakefektifan Pemberian ASI dengan Post SC atas Indikasi Preeklampsia Alvina, Alvina; Umar, Ahmad Farid; Herlina, Herlina
Jurnal Persada Husada Indonesia Vol 11 No 42 (2024): Jurnal Persada Husada Indonesia
Publisher : STIKes Persada Husada Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56014/jphi.v11i42.401

Abstract

Post Partum is the period after labor and birth of the baby, placenta and membranes that are needed to restore the uterine organs to the way they were before pregnancy and takes approximately 6 weeks. Sectio Caesarea is a delivery procedure to remove the baby through an incision in the abdomen and uterus. Preeclampsia or what is usually called pregnancy with hypertension, is not like hypertension in general but is closely related to high morbidity and mortality rates for both the fetus and mother. Breast milk is the best food for babies who do not have food intake to replace breast milk. The subjects in the case study used 2 clients who experienced ineffective breastfeeding in the Ponek Room at Bekasi City Regional Hospital. The design in this research uses a qualitative approach with descriptive study analysis. The results of research conducted on the client Mrs. D & Mrs. S is that in this study the same 5 diagnoses were found, namely impaired comfort and pain, activity intolerance, ineffectiveness of breastfeeding, risk of ineffective peripheral perfusion and risk of infection. The diagnostic intervention that is the focus is the ineffectiveness of breastfeeding. Implementation carried out on 2 clients, namely assessing the condition of the client's breasts and nipples, carrying out and teaching breast care and oxytocin massage, encouraging mothers to breastfeed their babies as often as possible, involving husbands and families about breast care, providing education about breast milk. The evaluation of the 2 clients has been completed.
Analisis Terjadinya Tindak Pidana Penipuan Melalui Platform Media Sosial Alvina, Alvina; Pramesti, Anggita Hanum; Fatikah, Azka Lulu; Kurniawati, Kurniawati
VIVA THEMIS Vol 7, No 2 (2024): VIVA THEMIS
Publisher : Universitas Sang Bumi Ruwa Jurai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24967/vt.v7i2.3387

Abstract

Seiring dengan perkembangan zaman prilaku krimanalitas di Tengah Masyarakat pun mengalamiperkembangan tentunya bukan hanya sekedar pada motiv si pelaku, namun secara teknis jugamengalami perubahan yang sangat signifikan, dari kriminalitas yang sifatnya konvensional dandilakukan dengan cara langsung (face to face) berubah menjadi digital (tidak perlu secaralangsung) hal ini biasa disebut dengan online, pola kriminalnya yakni dengan melaakukanpenipuan secara online melalui media social maupun media telekomunikasi. Sangat menarik bilapersoalan ini dibahas secara mendalam namun sederhana, dikarenan tindak criminal hasilpengebangan teknologi modern ini memunculkan KUHAP baru tentang cyber crime, sehinggamunculah ide untuk melakukan penelitian yang dituangkan dalam sebuah jurnal ilmiah dengantitik fokuska pada Tindak Pidana Penipuan melalui Platform Media social. Dalam jurnal ini akandibahas tentang factor penyebab serta Upaya penegaakkan dan pencegaahan Tindak Pidanatersebut. Pendekatan library merupakan Teknik penelitian yang diambil, dan dianalisis secarakualitatif, Memang sangat sederhana namun semoga dapat menyajikan jurnal yang menariksehingga dapat dikembangkan di kemudian hari . serta dapat memberikan analisis factor penyebabterjadinya tindak pidana uga mampu meberikan penyadaran kepada Masyarakat tentangbahayanya kelalaian penggunaan media social demi mencegahnya tindak pidan aini terjadi.
PENYULUHAN DAN PEMERIKSAAN HIPERPLASIA PROSTAT TERHADAP LANSIA PRIA di CIANGSANA dan NAGRA Krismanuel, Hari; Tjhin, Purnamawati; Agil, Nadifa; Suparjo, Tjhang; Alvina, Alvina
Jurnal Pengabdian Masyarakat Trimedika Vol. 1 No. 1 (2024)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v1i1.19014

Abstract

Prostate hyperplasia is a condition in which there is hyperplasia of the stromal and epithelial cells of the prostate gland. This condition can be experienced by around 20% of men aged 41-50 years, 50% of men aged 51-60 years, up to more than 90% of men aged >80 years. As human life expectancy increases, the number of elderly people in society increases. This causes more and more elderly men to experience prostate hyperplasia. This condition is also experienced by people in the Ciangsana and Nagrak area. Meanwhile, the level of public knowledge regarding the symptoms and signs of prostate hyperplasia is still lacking. This situation causes a lack of public awareness about seeking treatment and increases the anxiety experienced by sufferers. The aim of this PKM is to increase public knowledge of the symptoms and signs of prostate hyperplasia and to screen for prostate hyperplasia among elderly men aged 60 years or more in the Ciangsana and Nagrak areas. This PKM method uses an education, preceded by a pre-test before education and a post-test after education. After that, a digital rectal examination is carried out to diagnose Prostate Hyperplasia. The data obtained consisted of pre-test and post-test results as well as data on Prostate Hyperplasia sufferers from counseling participants. The conclusion obtained in the form of Prostate Hyperplasia education increases the knowledge and level of awareness of counseling participants and the percentage of Prostate Hyperplasia sufferers from male elderly participants in Ciangsana and Nagrak is quite high (64.52%). The implication of this PKM is that people can detect early symptoms and signs of Prostate Hyperplasia and immediately go to a health facility.
PENYULUHAN ANEMIA DEFISIENSI BESI PADA REMAJA PUTRI DI DESA NAGRAK KABUPATEN BOGOR Mashabi, Yasmine; Alvina, Alvina; Ferina, Mutiara; Amalia, Husnun; Zalfa, Afifah; Yuliarsa, Cyntha Nasyanda; Ferdhian, Farrel
Jurnal Pengabdian Masyarakat Trimedika Vol. 2 No. 1 (2025)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v2i1.21791

Abstract

Anemia adalah suatu keadaan di mana jumlah sel darah merah dan kapasitas pengangkutan oksigennya tidak mencukupi untuk memenuhi kebutuhan tubuh secara fisiologis. Penyebab anemia pada remaja sering dikaitkan dengan kebiasaan makan, menstruasi, dan pengetahuan. Selain itu, perhatian pada remaja dan wanita dewasa tidak secukup perhatian yang diberikan pada wanita hamil dan balita. Oleh karena itu, langkah-langkah efektif harus diambil untuk memberantas masalah gizi ini terutama untuk meningkatkan kualitas hidup dengan cara memberikan edukasi dengan metode penyuluhan serta menilai keberhasilannya dengan memberikan pre tes sebelum edukasi serta post tes setelah edukasi. Hasil dari edukasi ini sendiri berhasil meningkatkan pengetahuan remaja putri yaitu dengan adanya peningkatan pengetahuan hampir pada semua responden 21 orang (70%). Gambaran hasil pengetahuan menunjukkan bahwa kategori baik pada pre-test menunjukkan sebesar 77% responden, dan pada kategori baik pada post-test sebesar 97% responden. Dari hasil tersebut, terlihat adanya kenaikan pada kategori pengetahuan, baik sebelum dilakukan dan sesudah dilakukan edukasi Tujuan dari penyuluhan ini sendiri agar remaja putri dapat menerapkan perilaku pencegahan anemia sejak dini untuk dapat mempersiapkan diri sebaik mungkin dalam menghadapi kehamilan dan persalinan.