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All Journal PROSIDING SEMINAR KIMIA Science and Technology Indonesia JURNAL ATOMIK Jurnal Abdimas Mahakam
Hairani, Rita
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Energy Environmental Science Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Physics Public Health Social Sciences

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UJI FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ETANOL BATANG BAJAKAH (Uncaria cordata (Lour.) Merr.) TERHADAP Artemia salina L. Wardani, M. Rizky; Erwin, Erwin; Hairani, Rita
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Uncaria is a genus of plants that grows in the Kalimantan forest. Many species in this genus are used as traditional medicines, so this genus is interesting to be studied for its chemical compound content. One species in this genus is Uncaria cordata which is also known as Bajakah plant. The aim of this study was to determine the content of secondary metabolite compounds and the level of toxicity of the ethanol extract of U. cordata stems on Artemia salina L. The methods used in this research were extraction, phytochemical tests and toxicity test using the Brine Shrimp Lethality Test (BSLT) method. The results of the phytochemical test showed that the ethanol extract of U. cordata stems contained alkaloids, triterpenoids, phenolics, flavonoids, quinones, and saponins. Furthermore, according to of the toxicity test showed that the ethanol extract of U. cordata stems had toxicity level of 75.03 ppm in the toxic category (LC50 < 1000 ppm). Based on these results, it can be concluded that the ethanol extract of U. cordata stems has the potential to have bioactivity because it is toxic to Artemia salina L. shrimp larvae. Keywords: Bajakah, Phytochemicals, Secondary Metabolites, Toxicity, Uncaria cordata
POTENSI AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL BUNGA ASOKA (Ixora coccinea L.) Ramadhan, Aulia; Saleh, Chairul; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 9 No 1 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i1.1273

Abstract

Extraction of asoka (Ixora coccinea L.) flowers, phytochemical screening, and antioxidant activity of methanol extract of asoka flowers have been conducted. This study aimed to determine the content of secondary metabolites in the methanol extract of asoka flowers and its antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The phytochemical screening test revealed that the methanol extract of asoka flowers contained secondary metabolites such as flavonoids, alkaloids, triterpenoids and saponins. With 1 mg/mL, the methanol extract exhibited potential as an antioxidant with an inhibition percentage of 88.10% while vitamin C as a standard used in this study at 1 mg/mL showed an antioxidant activity of 99.23%.
PENGHAMBATAN AKTIVITAS α-GLUKOSIDASE DARI EKSTRAK METANOL BUNGA BUGENVIL (Bougainvillea glabra Choisy) Puspitasari, Intan Dessy; Saleh, Chairul; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 9 No 1 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i1.1276

Abstract

The test of Phytochemical screening and antidiabetic activity of methanol extract of bugenvil (Bougainvillea glabra Choisy) flower against α-glucosidase inhibition have been conducted. This study aims to determine the content of secondary metabolite compounds and the effectiveness of the methanol extract of bugenvil flower against α-glucosidase activity. Phytochemical test showed that the methanol extract contained secondary metabolite compounds namely alkaloids, flavonoids, steroids, phenolics and saponins. By 50 µg/mL, the methanol extract of bugenvil flower can inhibit α-glucosidase activity with a percent inhibition value of 79.42% while acarbose as a positive control in this study exhibited antidiabetic activity against α-glucosidase of 99.30% at a concentration of 0.00006 µg/mL.
Strategi Peningkatan Kualitas Pembelajaran Kimia bagi Siswa SMA Negeri 1 Muara Badak melalui Praktikum Kimia Hairani, Rita; Koesnarpadi, Soerja; Wirawan, Teguh; Ruga, Ritbey; Ersanto, Tri Edi
Jurnal Abdimas Mahakam Vol. 8 No. 02 (2024): Juli
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/jam.v8i02.2595

Abstract

Tersedianya sarana dan prasarana di tingkat sekolah menengah atas (SMA) untuk melaksanakan praktikum kimia berupa laboratorium serta alat dan bahan praktikum kimia sangatlah penting terhadap peningkatan kualitas pembelajaran bagi siswa. SMA Negeri 1 Muara Badak merupakan salah satu SMA yang berada di kecamatan Muara Badak Kalimantan Timur dan memiliki sarana laboratorium untuk melakukan praktikum. Namun kegiatan praktikum kimia terkendala untuk rutin dilaksanakan yang dikarenakan kurang memadainya alat dan bahan praktikum di sekolah tersebut. Sehubungan dengan kendala yang dihadapi dan sebagai upaya implementasi salah satu poin Tri Dharma Perguruan Tinggi, yaitu pengabdian kepada masyarakat, maka tim dosen Jurusan Kimia FMIPA Universitas Mulawarman pada 5 Juni 2023 berinisiatif untuk melakukan pendampingan praktikum kimia dan juga menyediakan alat dan bahan praktikum kimia yang dapat dilaksanakan di sekolah tersebut. Kegiatan ini juga diparalelkan dengan penyampaian materi mengenai keselamatan dan kesehatan kerja (K3) di laboratorium oleh pihak PT. Global Environment Laboratory (PT. GEL) Samarinda yang merupakan mitra kerjasama. Pada kegiatan ini, pengumpulan data menggunakan instrument berupa angket pre-test dan post-test yang disebarkan ke 30 siswa SMA Negeri 1 Muara Badak. Hasil analisis terhadap jawaban angket pre-test menunjukkan bahwa sekitar 71% siswa setuju bahwa kimia adalah subjek yang menarik dan 72% siswa setuju bahwa kimia berguna untuk memahami fenomena sehari-hari. Selanjutnya, berdasarkan analisis data angket post-test menunjukkan bahwa sebagian besar siswa setuju dengan uraian yang dijabarkan di angket. Secara keseluruhan hasil analisis angket-angket tersebut menunjukkan bahwa kegiatan yang telah dilakukan memiliki dampak yang cukup baik bagi siswa SMA Negeri 1 Muara Badak dalam hal motivasi belajar terhadap pembelajaran kimia melalui metode praktikum.
SKRINING FITOKIMIA DAN UJI TOKSISITAS MENGGUNAKAN BRINE SHRIMP LETHALITY TEST (BSLT) DARI EKSTRAK DIKLOROMETANA RIMPANG TEMU KUNCI (Boesenbergia rotunda) Jonathan, Jonathan; Ruga, Ritbey; Hairani, Rita
JURNAL ATOMIK Vol 9 No 2 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i2.1407

Abstract

The rhizome of Boesenbergia rotunda (temu kunci) is one of medicinal plants having potential for medicinal, supplementary food and drink due to its biological activities. The aims of this research are to identified the secondary metabolite compounds present in the dichlorometane extract of finger-root rhizomes through phytochemical screening using thin layer chromatography (TLC) method and to investigated its toxicity against Artemia salina L. shrimp larvae by using Brine Shrime Lethality Test (BSLT). The result of phytochemical analysis showed that the dichloromethane extract contains secondary metabolite compounds including flavonoids, phenolics and triterpenoids while the toxicity test of the extract showed its LC50 value of 303.68 µg/mL. It was indicated that the extract could be classified as toxic.
AKTIVITAS ANTIOKSIDAN TUMBUHAN GENUS MANGIFERA DENGAN METODE DPPH (1,1-diphenyl-2-picrylhydrazyl) : MINI REVIEW Jannah, Nurul; Hairani, Rita; Marliana, Eva
JURNAL ATOMIK Vol 9 No 2 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i2.1394

Abstract

Mangifera is a genus of the Anacardiaceae family of mangoes spread across Sumatra, Kalimantan, Java, and Bali. Several species of the genus Mangifera have been extensively researched on phytochemistry and antioxidant activity using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The study explains that several species of the genus Mangifera contain secondary metabolite compounds, such as flavonoids, phenolics, tannins, saponins, alkaloids, triterpenoids, and quinones. The results of several studies explain that the Mangifera genus has antioxidant activity with an inhibitory concentration (IC50) value generally <50 ppm, which is a strong category, so it has the potential to be an antioxidant. Keywords : Mangifera, phytochemical screening, antioxidant activity
ULASAN KANDUNGAN METABOLIT SEKUNDER DAN KAJIAN BIOAKTIVITAS PADA RUMPUT TEKI (Cyperus rotundus L.) Nurbah, Sahriana Putri; Sitorus, Saibun; Hairani, Rita
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Nutgrass (Cyperus rotundus L.) is one of the Cyperaceae family plants which is this plant belongs to weed. However, it is often used by the Chinese people as a traditional medicine. This review aimed to determine the bioactivity of nutgrass based on their secondary metabolite content. This review was carried out by Literature Review Article method from various journals through Google Scholar and Science Direct. The results of this review indicated that nutgrass has important bioactivities such as antioxidants, antidiabetic, anti-inflammatory, anticancer and antibacterial. Based on the review of those articles, it can be concluded that nutgrass has several important potency for human health to be further studied. Keywords: Cyperus rotundus L, Bioactivity, Secondary Metabolites
ISOLATION OF LIPASE PRODUCING BACTERIA FROM HOT SPRINGS OF LONG KALI Alawiyah, Dessy Noor; Astuti, Winni; Hairani, Rita
JURNAL ATOMIK Vol 6 No 1 (2021)
Publisher : Jurusan Kimia FMIPA UNMUL

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Abstract

Isolasi bakteri penghasil lipase dari sumber air panas Long Kali dilakukan dengan menyeleksi koloni bakteri pada media Nutrient Agar (NA) yang mengandung Rhodamin B dan minyak zaitun. Hasil isolasi menunjukkan 5 dari 14 isolat bakteri mampu menghasilkan lipase. lima isolat tersebut diuji aktivitas lipase dengan metode titrimetri, isolat dengan kode 14 memiliki aktivitas tertinggi dengan aktivitas 2,20 Unit/mL.
AKTIVITAS ANTI-Staphylococcal SECARA IN VITRO EKSTRAK DIKLOROMETANA DARI RIMPANG TEMU KUNCI (Boesenbergia rotunda) TERHADAP Staphylococcus aureus ATCC 25923 Matutu, Deni Ari; Hairani, Rita; Ruga, Ritbey
JURNAL ATOMIK Vol 10 No 1 (2025)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v10i1.1404

Abstract

The rhizome of temu kunci (Boesenbergia rotunda) is one of the plants used by the local people in Indonesia as a traditional medicine. This study aimed to identify the secondary metabolite compounds contained in the dichloromethane extract with phytochemical screening and investigate its antibacterial activity against test bacteria Staphylococcus aureus ATTC 25923 was carried out by agar diffusion method with modification where tetracycline as a positive control and ethanol as a negative control. The phytochemical screening showed the dichloromethane extract contains secondary metabolites such as alkaloids, flavonoids, phenolics and triterpenoids. With 1 mg/mL of dichloromethane extract revealed its antibacterial activity against S. aureus with inhibitory zone value of 15.0 ± 0.0 mm while its MIC value of the extract was 0.031 ± 0.0 mg/mL toward of tested bacteria. In addition, tetracycline as a positive control at 0.5 μg/mL exhibited its antibacterial potential with an inhibitory zone value of 22.0 ± 0.0 mm and its MIC value of 0.016 ± 0.577 µg/mL.
AKTIVITAS ANTIBAKTERI BUNGA KERTAS (Bougainvillea glabra): REVIEW ARTIKEL Supratman, Rafif Ghanaifalah Dely; Hairani, Rita; Ruga, Ritbey
PROSIDING SEMINAR KIMIA Vol 3 No 2 (2025): Prosiding SNKT 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Herbal or medicinal plants contain many diverse phytochemical compounds and provide various biological effects. One of them is Bougainvillea glabra which is often used in traditional medicine in various countries due to the plant has bioactive compounds, one of which is antibacterial. This study aims to determine the antibacterial activity of Bougainvillea glabra. The methodology used was a literature study using several scientific articles about antibacterial activity published in the last ten years and published in national and international scientific journals as library sources through searches on Google Scholar site. The results showed that Bougainvillea glabra had inhibitory activity against the bacteria Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Bacillus cereus, but it had not inhibitory activity against the bacteria Listeria monocytogenes and Salmonella sp. Keywords : Bougainvillea glabra, bioactive, antibacterial
Co-Authors Alawiyah, Dessy Noor Chairul Saleh Daniel Djihan Ryn Pratiwi, Djihan Ryn Ersanto, Tri Edi Erwin Erwin Eva Marliana, Eva Indra Masmur Jonathan Jonathan Magdaleni, Agustina Rahayu Masmur, Hestina Matutu, Deni Ari Nurbah, Sahriana Putri Nurul Jannah Puspitasari, Intan Dessy Ramadhan, Aulia Ritson Purba, Ritson Ruga, Ritbey Saibun Sitorus Soerja Koesnarpadi Subur P Pasaribu Supratman, Rafif Ghanaifalah Dely Teguh Wirawan, Teguh Wardani, M. Rizky Winni Astuti, Winni