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All Journal Padjadjaran Journal of Dentistry B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah
Nur'aeny, Nanan
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effectiveness of Steroid and Non-Steroid Mouthwashes for Oral Lichen Planus: A Systematic Review Purnomo, Luthfiyyah Andini; Zakiawati, Dewi; Nur'aeny, Nanan
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 12, No 1 (2025): Volume 12 No 1, Juni 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v12i1.1862

Abstract

Definitive management of Oral lichen planus (OLP) remains challenging due to its intractable nature and unclear cause. Steroid and non-steroid mouthwash preparations are recommended for OLP, especially for diffuse or difficult-to-access lesions. This review aims to evaluate the efficacy of available steroid and non-steroid anti-inflammatory mouthwashes in managing OLP focusing on pain reduction, lesion size reduction, and possible side effects. A systematic literature search from 2012- 2022 was conducted using Scopus, PubMed, and ScienceDirect, following PRISMA guidelines. Nine RCTs included with steroid mouthwashes (dexamethasone, triamcinolone) show promise as effective treatment options for reducing pain and lesion size in OLP, while non-steroid mouthwash (cyclosporine) demonstrates better long-term remission. Natural adjuvant therapies, like nanocurcumin gel, quercetin capsules, and SE-ACE tablets can support the use of steroid mouthwashes. Additionally, fluconazole capsule, itraconazole capsule, and nystatin suspension can be used as adjuvant therapy to prevent secondary candidiasis infection caused by steroid mouthwashes. The risk assessment of bias using the Joanna Briggs Institute (JBI) Critical Appraisal Tools showed seven articles with a low risk of bias and two with a moderate risk. However, heterogeneity in the type, dose, trial duration, and outcome measures limit direct comparisons of treatment effectiveness.
Nutritional status of vitamin B12 on small group of dental students based on food frequency questionnaire Syafiqah, Izzatul; Nur'aeny, Nanan; Herawati, Erna
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November 2016
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.589 KB) | DOI: 10.24198/pjd.vol28no3.13621

Abstract

Introduction: Vitamin B12 plays an important role in general cell metabolism. Vitamin B12 also essential for normal hematopoietic, importance in maintaining the integrity of nervous system and formation of nervous system. Even though vitamin B12 is essential for good health, some people may not be getting enough intake of vvitamin B12. The purpose of this research is to get information about the nutritional status of vitamin B12 on dental students based on food frequency questionnaire. Methods: Method used in this research were descriptive non experimental of 30 dental students from Faculty of Dentistry in Universitas Padjadjaran. All samples were given the food frequency questionnaire and recorded the amount of food were taken within 7 days. The consumption of vitamin B12 daily were calculated by using Nutrisurvey software. Results: Among 30 students, there were 7 students who were in lack of consumption of vitamin B12, 14 students or almost half of them who were in normal level and 9 students who were in high level of Vitamin B12 consumption. Conclusion: The Nutritional Status of Vitamin B12 on Small Group of Dental Students Based on Food Frequency Questionnaire were mostly in normal level.
The most common and predicted diagnosis or conditions of oral mucosal lesions among elementary school children Wahyuni, Indah Suasani; Putri, Fidya Meditia; Fatriadi, Fajar; Nur'aeny, Nanan; Hidayat, Wahyu
Padjadjaran Journal of Dentistry Vol 33, No 2 (2021): July 2021
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol33no2.15977

Abstract

Introduction: Oral mucosal health is part of general health that also requires attention. Research on oral mucosal in children has not widely conducted, especially in the Jatinangor sub-district as one of the educational centres in West Java.  This study was aimed to determine the most common and predicted the diagnosis or conditions of oral mucosal lesions among elementary school children. Methods: This research was a cross-sectional study. The purposive sampling method was used, in which only the fifth-grade students from the elementary school cluster near the centre of the Jatinangor sub-district were involved. The inclusion criteria were healthy condition, cooperative, able to communicate with the examiner, and obtained permission from the parent/guardian. The oral mucosal lesions were examined using disposable dental tools and a white light headlamp. Oral mucosal lesions found on examination defined as oral diseases and normal variation of oral mucosal. Results: A total of 226 students, consisting of 115 males and 111 females, were included in this study. The oral mucosal lesions found were described as follows: 100 cases of pseudomembranous plaque, 106 cases of macula, 56 cases of ulceration, 45 cases of cheek biting, and another fewer lesions. The lesions' diagnosis was coated tongue for the pseudomembranous plaque, physiologic pigmentation for the macula, aphthous stomatitis/traumatic ulcer/angular cheilitis for ulcers, linea alba for cheek biting, and others. Conclusion: The most commonly found oral mucosal lesions were macula which is diagnosed as macular hyperpigmentation, followed by pseudomembranous plaque which is diagnosed as coated tongue.
Serum IL-6 levels of atopic patients with recurrent aphthous stomatitis (RAS) Nur'aeny, Nanan; Sufiawati, Irna; Suwarsa, Oki; Gurnida, Dida Akhmad
Padjadjaran Journal of Dentistry Vol 31, No 1 (2019): March 2019
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.764 KB) | DOI: 10.24198/pjd.vol31no1.21223

Abstract

Introduction: Atopy is a genetic tendency of allergic condition with specific clinical manifestations such as atopic dermatitis (AD), allergic rhinitis (AR), and bronchial asthma (BA). Atopic individuals might experience other health problems that coincide with atopic manifestations, including the appearance of recurrent aphthous stomatitis (RAS) which is an oral mucosal disease that can also be influenced by allergies. This study was aimed to be the preliminary study regarding the level of IL-6 serum in atopic patients who were also having RAS. Methods: Thirty subjects were recruited and grouped into three groups with ten subjects each were group of atopic (dermatitis, allergic rhinitis, or bronchial asthma) with RAS, atopic without RAS, and control. Blood specimens were obtained with an approved institutional board review protocol. This research was cross-sectional research with consecutive sampling method conducted at Dr Hasan Sadikin Hospital Bandung. Results: There were significant differences in IL-6 log levels in all three groups (p < 0.001). The higher IL-6 levels in the group of atopic with RAS might be due to the influence of atopy because this condition can increase the acute inflammation of RAS. IL-6 is a pro-inflammatory marker found in the circulation of atopic and RAS patients. Conclusion: Serum IL-6 levels in the group of atopic patients with RAS is higher than in other groups. Keywords: Serum, IL-6, atopic, recurrent aphthous stomatitis
Distribution of oral ulceration cases in Oral Medicine Integrated Installation of Universitas Padjadjaran Dental Hospital Zakiawati, Dewi; Nur'aeny, Nanan; Setiadhi, Riani
Padjadjaran Journal of Dentistry Vol 32, No 3 (2020): November 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no3.23664

Abstract

Introduction: Oral ulceration defines as discontinuity of the oral mucosa caused by the damage of both epithelium and lamina propria. Among other types of lesions, ulceration is the most commonly found lesion in the oral mucosa, especially in the outpatient unit. Oral Medicine Integrated Installation (OMII) Department in Universitas Padjadjaran Dental Hospital serves as the centre of oral health and education services, particularly in handling outpatient oral medicine cases. This research was the first study done in the Department which aimed to observe the distribution of oral ulceration in OMII Department university Dental Hospital. The data is essential in studying the epidemiology of the diseases. Methods: The research was a descriptive study using the patient’s medical data between 2010 and 2012. The data were recorded with Microsoft® Excel, then analysed and presented in the table and diagram using GraphPad Prism® Results: During the study, the distribution of oral ulceration cases found in OMII Department was 664 which comprises of traumatic ulcers, recurrent aphthous stomatitis, angular cheilitis, herpes simplex, herpes labialis, and herpes zoster. Additionally, more than 50% of the total case was recurrent aphthous stomatitis, with a precise number of 364. Conclusion: It can be concluded that the OMII Department in university Dental Hospital had been managing various oral ulceration cases, with the most abundant cases being recurrent aphthous stomatitis.
Co-Authors Dewi Zakiawati, Dewi Dida Akhmad Gurnida Erna Herawati, Erna Fajar Fatriadi Fidya Meditia Putri, Fidya Meditia Indah Suasani Wahyuni Irna Sufiawati Izzatul Syafiqah, Izzatul Oki Suwarsa Purnomo, Luthfiyyah Andini Riani Setiadhi Wahyu Hidayat