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Pengaruh Penyuluhan terhadap Kepadatan Aedes aegypti dalam Pencegahan Demam Berdarah Zulaikhah, Siti Thomas; Yusuf, Iwang
Kes Mas: Jurnal Fakultas Kesehatan Masyarakat Vol 12, No 1 (2018): Kes Mas: Jurnal Fakultas Kesehatan Masyarakat
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.209 KB) | DOI: 10.12928/kesmas.v12i1.6627

Abstract

Background: Dengue infection is a public health problem and until now, the dengue eradication efforts have not been successfuly. In Indonesia, the incidence is still high and widely transmitted there fore the more intensive vector control is required. The purpose of this study was to verify that the counseling program about mosquitonest eradication effect the density of Aedes. Method: The research was quasi experiment using one group pre and post test design, interventions about counseling of mosquito to eradication. Samples were gathered from health center around Ngaliyan area which consisted of 6 districts. Each district was taken 100 houses by simple random sampling, so the total samples are 600 and each samples were testedor the presence of Aedes aegypti’s larvaes. Pretest was conducted on May 2013 and postest on August 2013 by conducting entomological survey to determine the density of Aedes aegypti’s larvae. Respondents are received 3 times counseling. Results: Data about Larva Free Index (ABJ), Container Index (CI), House Index (HI) and Breteau Index (BI) were tested for normality using Shapiro Wilk, and all were normally distributed (p>0.05), the data were analyzed using t-paired test. The result of Larva Free Index variable analysis obtained were p=0.011, CI p=0.000, HI p=0.035 and BI p=0.004. Conclusion: Counseling about mosquito eradication effected on Aedes aegypti’s larvae so it can prevent the outbreak of dengue fever.
Pengaruh Penyuluhan terhadap Kepadatan Aedes aegypti dalam Pencegahan Demam Berdarah Zulaikhah, Siti Thomas; Yusuf, Iwang
Kes Mas: Jurnal Fakultas Kesehatan Masyarakat Vol 12, No 1 (2018): Kes Mas: Jurnal Fakultas Kesehatan Masyarakat
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.209 KB) | DOI: 10.12928/kesmas.v12i1.6627

Abstract

Background: Dengue infection is a public health problem and until now, the dengue eradication efforts have not been successfuly. In Indonesia, the incidence is still high and widely transmitted there fore the more intensive vector control is required. The purpose of this study was to verify that the counseling program about mosquitonest eradication effect the density of Aedes. Method: The research was quasi experiment using one group pre and post test design, interventions about counseling of mosquito to eradication. Samples were gathered from health center around Ngaliyan area which consisted of 6 districts. Each district was taken 100 houses by simple random sampling, so the total samples are 600 and each samples were testedor the presence of Aedes aegypti’s larvaes. Pretest was conducted on May 2013 and postest on August 2013 by conducting entomological survey to determine the density of Aedes aegypti’s larvae. Respondents are received 3 times counseling. Results: Data about Larva Free Index (ABJ), Container Index (CI), House Index (HI) and Breteau Index (BI) were tested for normality using Shapiro Wilk, and all were normally distributed (p>0.05), the data were analyzed using t-paired test. The result of Larva Free Index variable analysis obtained were p=0.011, CI p=0.000, HI p=0.035 and BI p=0.004. Conclusion: Counseling about mosquito eradication effected on Aedes aegypti’s larvae so it can prevent the outbreak of dengue fever.
Smoking as Risk Factors to Dry Eye Syndrome Pritasari, Alteriana Mydriati Sita; Faida, Soraya Nur; Zulaikhah, Siti Thomas
KEMAS: Jurnal Kesehatan Masyarakat Vol 15, No 1 (2019)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v15i1.8611

Abstract

Cigarette smoke can damage the fat layer of the tear film lperoxidation. Dry eye syndromeis a cluster of disorders caused by an imbalance between production and excretionof tears, causing symptoms of discomfort in the eye. This study aims to related riskfactors smoke of dry eye syndrome. Analytic observational with cross sectional design,population of all visitors, officers and employees KAI Poncol station Semarang. Sampleof 60 respondents who meet the inclusion and exclusion criteria. Data about dry eye syndrome are examined using Schirmer I test, data on smoking were taken using a checklist.The data obtained were analyzed using chi-square test. Results of the respondentswho smoke and have dry eye syndrome was higher (80.6%) compared with non-smokers(25.0%). The results chi-square test p=0.000 (p<0.05), PR = 3.222 (95%CI:1.582-6.562).Smoke who risk 3.222 times higher chance of developing dry eye syndrome comparedwith do not smoke.
PERBEDAAN PENGETAHUAN PEROKOK AKTIF DAN PEROKOK PASIF TENTANG BAHAYA ROKOK Sari, Rita Kartika; Zulaikhah, Siti Thomas; PH, Livana
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 9 No 2 (2019): April
Publisher : LPPM STIKES KENDAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.975 KB) | DOI: 10.32583/pskm.9.2.2019.85-94

Abstract

Upaya untuk mengurangi terjadinya penyakit ISPA, diperlukan perilaku hidup sehat salah satunya yaitu dengan tidak merokok. Kenyataannya di masyarakat, merokok dijadikan suatu kebiasaan dan sulit dihentikan. Tujuan penelitian ini untuk mengetahui mengetahui gambaran pengetahuan, sikap, dan perilaku &nbsp;masyarakat dalam penggunaan rokok. Penelitian bertujuan untuk menganalisis perbedaan pengetahuan perokok aktif dan perokok pasif tentang bahaya rokok. Penelitian ini bersifat retrospektif menggunakan desain penelitian komparatif dengan pendekatan cross sectional. semua warga desa Margolinduk, Kecamatan Bonang, Kabupaten Demak Provinsi Jawa Tengah dan tinggal menetap &gt; dari 6 bulan yang berjumlah 100 orang. Penentuan besar sampel menggunakan teknik total sampling. Alat pengumpulan data menggunakan kuesioner. Analisis data menggunakan analisis univariat berupa distribusi frekuensi dan analisis bivariat menggunakan mann whitney. Hasil penelitian menunjukkan bahwa ada perbedaan pengetahuan antara perokok aktif dengan perokok pasif (p value= 0,000). Perlu upaya dari tenaga kesehatan untuk meningkatkan pengetahuan masyarakat tentang bahaya rokok terhadap kesehatan melalui pendidikan kesehatan pada semua tahap usia. &nbsp; Kata kunci : Pengetahuan, perokok aktif, perokok pasif. &nbsp; DIFFERENCE OF ACTIVE AND PASSIVE SMOKING KNOWLEDGE ABOUT CIGARETTE HAZARDS &nbsp; ABSTRACT Efforts to reduce the occurrence of ARI, a healthy lifestyle is needed, one of which is not smoking. In fact, in society, smoking is a habit and difficult to stop. The purpose of this study was to find out the description of knowledge, attitudes, and behavior of people in the use of cigarettes. The study aimed to analyze the differences in knowledge of active smokers and passive smokers about the dangers of smoking. This study is retrospective using a comparative research design with a cross sectional approach. all residents of Margolinduk village, Bonang Subdistrict, Demak Regency, Central Java Province, and lived for&gt; 6 months totaling 100 people. Determination of sample size using total sampling technique. The data collection tool uses a questionnaire. Data analysis using univariate analysis in the form of frequency distribution and bivariate analysis using Mann Whitney. The results showed that there was a difference in knowledge between active smokers and passive smokers (p value = 0,000). Efforts are needed from health workers to increase public knowledge about the dangers of smoking to health through health education at all stages of age.&nbsp; Keywords: Knowledge, active smokers, passive smoking.
Hubungan Pengetahuan, Perilaku dan Lingkungan Rumah dengan Kejadian Transmisi Tuberkulosis Paru di Wilayah Kerja Puskesmas Bandarharjo Semarang Zulaikhah, Siti Thomas; Ratnawati, Ratnawati; Sulastri, Neng; Nurkhikmah, Eli; Lestari, Novi Dian
Jurnal Kesehatan Lingkungan Indonesia Vol 18, No 2 (2019): Oktober 2019
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.18.2.81-88

Abstract

Latar belakang: Tuberkulosis paru adalah penyakit menular yang disebabkan oleh bakteri mycobacterium tuberculosis masih menjadi masalah kesehatan. Tingginya angka kejadian TB paru dapat dikarenakan adanya faktor tingkat pengetahuan yang rendah, perilaku kesehatan yang buruk dan lingkungan rumah seperti ventilasi, pencahayaan, kelembaban, kepadatan hunianyang tidakmemenuhi syarat. Tujuan penelitian ini untuk mengetahui variabel paling dominan berhubungan dengan transmisi kejadian TB paru di Wilayah Kerja Puskesmas Bandarharjo Kota Semarang.Metode: Desain penelitian observasional dengan pendekatan case control. Subjek penelitian terdiri dari 40 kasus dan 40 kontrol. Kasus merupakan penderita TB paru di Puskesmas Bandarharjo yang didiagnosis secara klinis dan laboratorik BTA positif dan tercatat dalam medical record dari bulan Agustus 2016 sampai Agustus 2017,kontrol merupakan tetangga kasus yang tidak terdiagnosis TB paru BTA positif dan anggota keluarga tidak menderita TB paru BTA positif. Teknik sampling menggunakan proporsional random sampling. Data yang terkumpul dianalisis dengan uji univariat menggunakan distribusi frekuensi, uji bivariat menggunakan Chi Square, uji Multivariat menggunakan Regresi logistik ganda. Hasil : Hasil uji bivariat variabel lingkungan yang terdiri dari luas ventilasi (p=0,000); kepadatan hunian (p=0,000); kelembaban (p=0,001); pencahayaan (p=0,001); suhu (p=0,001), sedang hasil variabel pengetahuan (p=0,002) dan perilaku (p=0,005). Hasil analisis multivariat variabel pengetahuan (OR=3,776); kepadatan hunian (OR=4,476); kelembaban (OR=4,030); pencahayaan (OR=3,635); suhu (OR=3,064); pengetahuan (OR=6,374); perilaku (OR=3,525).Simpulan: Lingkungan rumah, pengetahuan dan perilaku berhubungan dengan kejadian TB paru di wilayah kerja puskesmas Bandarharjo Semarang dan faktor yang paling dominan berhubungan adalah pengetahuan. ABSTRACTTitle: Relationship Knowledge, Behavior and Household Environmentwith the Transmission Insidence Pulmonary Tuberculosis in the Work Area of Bandarharjo Health Center SemarangBackground: Pulmonary tuberculosis, an infectious disease caused by the bacterium Mycobacterium tuberculosis remains a health problem. A higher incidence of pulmonary TB has been associated with low level of knowledge, poor health behavior and household environment such as ventilation, lighting, humidity, residential density. The purpose of this study was to identify the most dominant factor associated with the transmission pulmonary TB in the Bandarharjo Health Center in Semarang.Methods: The research was an observational one with a case control study. The case and the control of this research were both using 40 respondents. The case was patients clinically diagnosed with pulmonary TB and has a laboratory BTA+ and documented in the medical record from August 2016 to August 2017. The control was a neighbor of cases with no BTA+ (acid resistant bacilli) pulmonary TB and history of family no BTA+ of pulmonary TB. The proportional random sampling was applied. The collected data were analyzed using univariate test of frequency distribution, bivariateof Chi Square, multivariate oflogistic regression.Results: Bivariate test of environmental variables consisting of ventilation area (p = 0.000); occupancy density (p = 0.000); humidity (p = 0.001); lighting (p = 0.001); temperature (p = 0.001), while the results of the knowledge variable (p = 0.002) and behavior (p = 0.005). The multivariate analysis showed variable of knowledge (OR = 3.776); residential density (OR = 4.476); humidity (OR = 4.030); lighting (OR= 3.635); temperature (OR = 3.064); knowledge (OR = 6.374); behavior (OR = 3.525).Conclusion: The household environment, knowledge and behavior were related to the transmission incidence of pulmonary tuberculosis in the working area of Bandarharjo health center and the most dominant factor was knowledge.
Effects of Propolis Extract Supplementation during Pregnancy on Stress Oxidative and Pregnancy Outcome: Levels of Malondialdehyde, 8-Oxo-2′-Deoxogunosine, Maternal Body Weight, and Number of Fetuses Wibowo, Joko Wahyu; Fasitasari, Minidian; Zulaikhah, Siti Thomas
Jurnal Kedokteran Brawijaya Vol 31, No 3 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.03.5

Abstract

Oxidative stress is related to pregnancy complications that could increase maternal and infant mortality. This study aimed to determine the effect of propolis extract supplementation during pregnancy on oxidative stress level and pregnancy outcomes utilizing Malonedealdehyde (MDA) and 8-Oxo-2′-Deoxogunosine (8-OHdG) levels, maternal body weight, and the average number of fetuses as the parameters. The study was conducted by using a posttest only control group design on 24 pregnant Wistar rats, which were divided into four groups. Group I was control, Group II-IV were the treatment groups given propolis extract of 1.8mg, 3.6mg, and 7.2mg/200gBW/day, respectively. The standard feed given was AIN93G dose of 20g/day and distilled water ad libitum. Propolis extract was given using a gastric feeding tube every morning for 20 days. At the end of the treatment, body weight was meisured and blood collected for assessed MDA and 8-OHdG levels  by ELISA method  and then we performed abdominal surgery to count number of fetuses. The result are there were decreasing level of MDA and 8-OHDG by administration of propolis significantly (p<0.05) group: I: 2,04±0,091, II: 1,55±0,067, III: 1,05±0,176, IV: 0,73±0,075 (mmol/mL) (p=0.001); 8 OHdG level (ng/mL) group I: 10,02±0,403, II: 8,60±0,078, III: 7,89±0,051, IV: 7,53±0,063 (p=0,001). Average of maternal body weight (g) were increased: group I: 228,33±3,93, II: 237,17±4,36, III: 244,83±4,02, IV: 248,00±5,76 (p=0,001) and Average number of fetuses tend to increased as well, group I : 8,5±0,05, II: 7,8±0,41, III: 9,5±1,05, IV: 9,6±0,52 (p=0,02). The conclusion of this research are supplementation of propolis extract in pregnant rats can reduce oxidative stress and improve pregnancy outcomes.
Efek Paparan Asap Rokok Terhadap Kadar Total Antioxidant Capacity (TAC) Zulaikhah, Siti Thomas
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13 (2022): Nomor Khusus Januari 2021
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/%x

Abstract

Cigarette smoke caused by smoking is a factor in the risk of lung cancer, respiratory tract infections, and cardiovascular disease. Particles contained in cigarette smoke have the potential to increase the content of free radicals in the body and lower antioxidant levels. Levels of Total Antioxidant Capacity (TAC) reflects the amount of all antioxidants in the body and acts as a biomarker of antioxidant protection against free radicals. The purpose of this study was to investigate the impact of cigarette smoke exposure on TAC levels in wistar strain rats exposed to cigarette smoke. Design used is experimental with posttest only control group design. Independent variable in this research was cigarette smoke exposure and the dependent variable was levels of TAC. The study population is male wistar strain rats adapted in inter university research/ Penelitian Antar Universitas (PAU) Universitas Gajah Mada Yogyakarta Penelitian Antar Universitas (PAU) Universitas Gajah Mada Yogyakarta. Twelve male rats used in the study were randomly divided into 2 groups, group K1 (fed standard food et libitum + aquadest) K2 (fed standard food et libitum + aquadest + cigarette smoke exposure 3 buds/day). Treatments were given for 14 days. Day 15 rats blood are drawn to be checked for TAC using ELISA (Enzyme-Linked Immunosorbent Assay), data were analyzed using Mann Whitney test. Result: Mean Levels of TAC on K1: 1,79±0,5 mmol/L and K2: 0,56±0,06 mmol/L;. The results of the analysis obtained the p value: 0,003(
Pengaruh Asap Rokok Terhadap Kadar C-Reactive Protein (CRP) Zulaikhah, Siti Thomas
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13 (2022): Nomor Khusus Januari 2021
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/%x

Abstract

Smoking is a source of free radicals associated with DNA damage, and as the cause of various diseases. Smoking is a major risk factor for inflammation that can be measured by levels of C-Reactive Protein (CRP). High levels of free radicals can trigger the emergence of Reactive Oxygen Species (ROS). This condition can affect inflammatory mediators in the body, and trigger an inflammatory process characterized by increased levels of C-reactive protein (CRP). CRP can be used as an instrument to monitor the risk of cardiovascular disease complications in active smokers. The purpose of this study was to find out the impact of cigarette smoke exposure on CRP levels in wistar strain rats exposed to cigarette smoke. Design used is experimental with posttest only control group design. The independent variable in the study was exposure to cigarette smoke, while the variables were bound to CRP levels. The study population is male wistar strain rats adapted in inter university research/ Penelitian Antar Universitas (PAU) Universitas Gajah Mada Yogyakarta. Twelve male rats used in the study were randomly divided into 2 groups, group K1 (fed standard food et libitum + aquadest); K2 (fed standard food et libitum + aquadest + cigarette smoke exposure 3 buds/day). Treatments were given for 14 days. Day 15 rats blood are drawn to be checked for CRP levels using ELISA(Enzyme-Linked Immunosorbent Assay), data analyzed using the independent t- test. Mean CRP levels for K1: 3.2±0,28 mmol/L and K2:0, 56±0,06 mmol/L;. The results of the analysis obtained the p value: 0,000(
Mercury and its effect on human health: a review of the literature Siti Thomas Zulaikhah; Joko Wahyuwibowo; Arrizki Azka Pratama
International Journal of Public Health Science (IJPHS) Vol 9, No 2: June 2020
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (817.911 KB) | DOI: 10.11591/ijphs.v9i2.20416

Abstract

Mercury in human body is a free radical that can cause depletion of glutathione (GSH) and hoarding of H2O2, leading to shorten the age of erythrocytes and cause haemolysis. Approximately 90% organic form can be absorbed by the intestinal wall, while inorganic forms are only about 10%. The initial form can also penetrate the blood and placental barrier so that it can cause teratogenic effects and nervous disorders. The effects of mercury toxicity on humans depend on the chemical form of mercury, dosage, age of people exposed, length of exposure, entry into the body, fish diet and consumption of seafood. Mercury is able to bind sulfidril proteins in cells resulting in nonspecific cell injury or even cell death, cessation of microtubule formation, enzyme inhibition, oxidative stress, cessation of protein and DNA synthesis, and autoimmune responses. Classified into a very toxic metal, mercury can trigger the formation of ROS, hydrogen peroxide, lipid peroxidation, hydroxyl radicals that can inhibit enzymes, cell damage, DNA damage, protein structure damage, disruption on the body's antioxidant metabolism, especially superoxide dismutase (SOD) and glutathione peroxidase (GPx). Mercury exposure is associated with an increased risk of hypertension, myocardial infarction, coronary dysfunction, and atherosclerosis. This review is clearly in line to investigate the effect of mercury on human health based on previous research, article and other literature sources.
The Effect of Tender Coconut Water on Free Radical Due to Mercury Exposure Siti Thomas Zulaikhah; Joko Wahyu Wibowo
International Journal of Public Health Science (IJPHS) Vol 7, No 2: June 2018
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.758 KB) | DOI: 10.11591/ijphs.v7i2.11849

Abstract

Mercury pollution can results from gold mining. Furthermore, a continuous mercury exposure can trigger the formation of Reactive Oxygen Species (ROS) and interfere with the body's antioxidant metabolism. A high level of free radicals in the body can be characterized by a low level of an antioxidant enzyme. Prevention to avoid the impacts of mercury poisoning is better than treatment. Tender coconut water can eliminate ROS and improve antioxidant status. This study aimed to was to confirm that tender coconut water is able to decrease the free radical which is characterized by increased antioxidant enzyme GPx status. This study was designed as randomized pre- and posttest control group design, 40 traditional gold mining workers devided into 2 groups: the control and treatment groups. After the pre test of GPx level, the workers were either given tender coconut water at the dose of 450 m L or water for 4 weeks every day. Four weeks after the pre-test, the level of GPx was assessed in the laboratory PAU-Gajahmada University. The post test results of the control group and treatments group were compared and analyzed using Man Whitney test. The mean levels of GPx post-test in the control group and treated group were 63.5±1.1 U/mL and 79.9±8.8 U/mL respectively. The analysis result obtained p-value 0.000 <0.05. Tender coconut water has an effect on free radicals due to to mercury exposure. Tender coconut water can be consumed daily to prevent degenerative diseases caused by mercury exposure.
Co-Authors Aini, Helmia Fitri Nurul Ali Djamhuri Amellia, Nazzala Luthfin Arif, Mohamad Arrizki Azka Pratama Artanti, Sekar Arum Caesara, Vidya Rahayunda Cahyani, Adhisa Rizky Chodidjah Choirinnisa, Luluk Damayanti, Indy Anindya David Akbar M Dea, Salsabila Ratna Dewa, Yusuf Kusuma Dhanny Rona Etika Egan, Zahir Khan Gaddy Shaquille Eka Norma Anggorowati, Eka Norma Eko Naning Sofyanita Elly Noerhidajati Elly Noerhidayati Elok Faiqoh Endang Surani, Endang Erinda, Adysa Erwin Budi Cahyono Faida, Soraya Nur ferdi ardiansyah, ferdi Fitrianisa, Nadya Ghani, Muhammad Firman Hariyanto, Ropik Iis Aisyah Sutisna Imam Djamaludin Mashoedi Indriatno, Anang Wiwik Isaroh, Nila Latifatul Iwang Yusuf Joko Wahyu Wibowo Joko Wahyu Wibowo Joko Wahyu Wibowo Joko Wahyu Wibowo Joko Wahyu Wibowo Joko Wahyu Wibowo Joko Wahyuwibowo Khairunnisa, Sekarayu Septia Khoirunnida Kurniasari, Linda Kurniawan, Yuwono Tulus Lestari, Novi Dian Livana Ph, Livana Lusito Lusito Masyhudi Masyhudi, Masyhudi Menik Sahariyani Minidian Fasitasari Minidian Fasitasari Muhammad Saugi Abduh Muhammad Ulil Fuad Mustika Rani Nafisyah, Nafisyah Nisaa, Salsabila Amarti Noorrahman, Handy Triya Nurkhikmah, Eli Octavia, Tania Pasid Harlisa Perez Wahyu Purnasari Prasetijono, Purwito Soegeng Prasetyo Bhakti H Pratami, Rani Windasari Prissanty, Anne Aninditha Pritasari, Alteriana Mydriati Sita Putra, Alexander Vito Dharma Raharja, Mediana Emilia Rahim, Denasa Dwi Sopandita Rahmadhani, Ilham Suci Ratnawati Ratnawati Ratnawati Ratnawati Ratnawati Ratnawati Reza Adityas Trisnadi Rohadi Rohadi Sampurna Sampurna, Sampurna Setyo Trisnadi Shinta, Sopia Silvyana Helmalia Putri Sita, Tiara Laras Sri Priyantini Sulastri, Neng Suparmi Suparmi Susilorini Susilorini Taufiqurrachman Nasihun Titiek Sumarawati Umami, Nurfarida Riza Wardhana, Naufal Al Faris Widianto, Fadhilla Dimas Yusuf, Iwang