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Harini, Ika Murti
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Perbedaan Kadar Laktat Dehidrogenase (LDH) pada Berbagai Derajat Keparahan Preeklampsia Novara, Tendi; Harini, Ika Murti; Sutrisno, Sutrisno
Jurnal Kedokteran Brawijaya Vol 30, No 4 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.175 KB) | DOI: 10.21776/ub.jkb.2019.030.04.7

Abstract

Preeklampsia adalah penyakit kehamilan akibat disfungsi plasenta serta merupakan penyebab kesakitan dan kematian maternal maupun perinatal di Indonesia. Laktat dehidrogenase (LDH) adalah enzim intraseluler yang dapat menandai adanya jejas pada sel dan jaringan. Penelitian ini bertujuan untuk mengetahui perbedaan kadar LDH pada berbagai derajat keparahan preeklampsia. Penelitian ini menggunakan desain analitik observasional dengan pendekatan kasus kontrol. Subjek dibagi menjadi 3 kelompok yaitu normotensi, preeklampsia ringan (PER) dan preeklampsia berat (PEB). Data dianalisis menggunakan uji Kruskal-Wallis dan Mann Whitney. Hasil penelitian didapatkan perbedaan kadar LDH antara kelompok normotensi dengan PER (p=0,031) dan antara normotensi dengan PEB (p=0,039) dengan kadar LDH pada PEB secara bermakna paling rendah dibandingkan dengan PER dan normotensi.
Perbedaan Kadar Kalsium Darah pada Kehamilan Preeklamsia dengan Kehamilan Normotensi Harini, Ika Murti; Novara, Tendi; Sutrisno, Sutrisno
Jurnal Kedokteran Brawijaya Vol 30, No 2 (2018)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2018.030.02.6

Abstract

Preeklamsia pada ibu hamil merupakan salah satu penyebab morbiditas dan mortalitas maternal dan perinatal baik di dunia maupun di Indonesia. Kadar kalsium darah yang rendah pada ibu hamil diduga berperan terhadap patogenesis preeklamsia. Penelitian ini bertujuan untuk mengetahui perbedaan kadar kalsium darah pada preeklamsia dengan kehamilan normotensi di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Studi analitik observasional dengan pendekatan case control pada tiga kelompok penelitian yaitu preeklamsia ringan (PER), preeklamsia berat (PEB), dan kehamilan normotensi sebagai kelompok kontrol. Jumlah subjek tiap kelompok berjumlah 21 orang. Sampel darah diambil dari vena antecubiti dan disentrifuge untuk diambil serumnya. Pengukuran kadar kalsium dilakukan dengan metode Chresol Pthalein Complex. Hasil pada penelitian ini didapatkan rerata kadar kalsium darah pada kelompok PEB paling rendah (8,34±0,32mg/dL) dan berbeda bermakna secara statitstik dibandingkan kelompok PER (8,59±0,33mg/dL) dan normotensi (8,71±0,31md/dL). Penelitian ini membuktikan potensi keterlibatan kalsium pada preeklamsia berat.
FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KEPATUHAN DIET PADA PASIEN DIABETES MELITUS TIPE 2 DI KECAMATAN SUMBANG BANYUMAS Ernawati, Dwi Arini; Harini, Ika Murti; Gumilas, Nur Signa Aini
Journal of Bionursing Vol 2, No 1 (2020)
Publisher : Fakultas Ilmu-ilmu Kesehatan Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.145 KB) | DOI: 10.20884/bion.v2i1.40

Abstract

Background problem: Diabetes Mellitus (DM) prevalence in Indonesia based on the results of basic health Research (RISKESDAS) year 2013 is 2.1%, in Central Java  18.33%. Banyumas District has an incidence rate of 1,417 in 2014 and Sumbang Sub-district has the highest incidence rate of DM type 2. Management in DM sufferers is integrated, including eating arrangements, physical activity, education, and medicines. Meal arrangement for patients with type 2 DM includes setting against 3J: number, type and meal schedule in a day. Patients with DM who have already run a diet program has not been able to control blood glucose properly. Food arrangement often fails due to the disobedience of sufferers in running their diet. Many factors affect dietary compliance, among them the level of education, level of knowledge, self-motivation, family support and the role of health workers.Objective: To determine the factors that affect the compliance of diet in diabetes mellitus type 2 patients in Sumbang Sub-district of Banyumas.Methods: The studies used are cross sectional, the level of compliance seen from 3J, i.e. precise amounts, precise types and precise schedules. Samples taken from DM patients who are in Prolanis present during laboratory examination in June 2019. Sampling technique using total sampling. Bound variables are the level of dietary compliance, the free variables are education levels, knowledge levels, self-motivation, family support and the role of health workers.Results: The number of samples was 32 people, who were obedient in a diet of 15 people (46.9%), who did not obey 17 people (53.1%). The P value of the factor variable factors affecting the diet is: age p = 0.411, sex p = 0.035, Job p = 0131, long DM p = 0.261, education level p = 0.035, knowledge level p = 0.036, self motivation p = 0.464, family support p = 0.314, and P Health worker, p = 0.452. Variables that have a meaningful relationship (P < 0.05) with dietary compliance levels are gender, level of education and level of knowledge. As for the variable age, employment, old DM, self-motivation, family support, and the role of health workers have an insignificant relationship (P > 0.05Conclusion: From 32 patients DM most have a level of diet compliance in the category of disobedient 17 people (53.1%), there is a meaningful relationship between gender, education level and level of knowledge with DM dietary compliance,
Co-Authors Ernawati, Dwi Arini Gumilas, Nur Signa Aini Novara, Tendi Sutrisno, Sutrisno