diff --git a/Lib/_pyrepl/simple_interact.py b/Lib/_pyrepl/simple_interact.py
index e686526870e364..8fb2359fb51e8a 100644
--- a/Lib/_pyrepl/simple_interact.py
+++ b/Lib/_pyrepl/simple_interact.py
@@ -156,6 +156,7 @@ def maybe_run_command(statement: str) -> bool:
             input_n += 1
         except KeyboardInterrupt:
             r = _get_reader()
+            r.cmpltn_reset()
             if r.input_trans is r.isearch_trans:
                 r.do_cmd(("isearch-end", [""]))
             r.pos = len(r.get_unicode())
diff --git a/Misc/NEWS.d/next/Library/2025-08-18-16-02-51.gh-issue-134869.GnAjnU.rst b/Misc/NEWS.d/next/Library/2025-08-18-16-02-51.gh-issue-134869.GnAjnU.rst
new file mode 100644
index 00000000000000..abb3579aa912d1
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2025-08-18-16-02-51.gh-issue-134869.GnAjnU.rst
@@ -0,0 +1 @@
+Fix an issue where pressing Ctrl+C during tab completion in the REPL would leave the autocompletion menu in a corrupted state.